Heparan sulfate proteoglycan in diffuse plaques of hippocampus but not of cerebellum in Alzheimer's disease brain.

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

1984 • 5,166 citations

Amyloid plaque core protein in Alzheimer disease and Down syndrome.

1985 • 4,276 citations

Amyloid β-peptide is produced by cultured cells during normal metabolism

1992 • 1,888 citations

Requirement of Heparan Sulfate for bFGF-Mediated Fibroblast Growth and Myoblast Differentiation

1991 • 1,507 citations

Cleavage of Amyloid β Peptide During Constitutive Processing of Its Precursor

1990 • 1,388 citations

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

1989 • 1,237 citations

Differential staining of acid glycosaminoglycans (mucopolysaccharides) by Alcian blue in salt solutions

1965 • 1,065 citations

Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease

1988 • 899 citations

Evidence that β-Amyloid Protein in Alzheimer's Disease Is Not Derived by Normal Processing

1990 • 895 citations

Processing of the Amyloid Protein Precursor to Potentially Amyloidogenic Derivatives

1992 • 737 citations

Isolation of a heparan sulfate-containing proteoglycan from basement membrane.

1980 • 672 citations

Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate.

1992 • 511 citations

Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.

1987 • 469 citations

Potentially Amyloidogenic, Carboxyl-Terminal Derivatives of the Amyloid Protein Precursor

1992 • 432 citations

Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related.

1985 • 431 citations

The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease.

1988 • 410 citations

Diffuse senile plaques occur commonly in the cerebellum in Alzheimer's disease.

1989 • 336 citations

A COMPARATIVE STUDY OF MODIFIED BIELSCHOWSKY, BODIAN AND THIOFLAVIN S STAINS ON ALZHEIMER'S NEUROFIBRILLARY TANGLES

1986 • 326 citations

The beta-amyloid protein precursor of Alzheimer disease has soluble derivatives found in human brain and cerebrospinal fluid.

1989 • 251 citations

Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein containing lesions of Alzheimer's disease and Down's syndrome

1990 • 245 citations

Isolation and characterization of amyloid P component from Alzheimer's disease and other types of cerebral amyloidosis.

1988 • 244 citations

Effects of Sulfate Ions on Alzheimer β/A4 Peptide Assemblies: Implications for Amyloid Fibril‐Proteoglycan Interactions

1992 • 211 citations

Proteoglycans in the pathogenesis of Alzheimer's disease and other amyloidoses

1989 • 211 citations

Chloroquine inhibits intracellular degradation but not secretion of Alzheimer beta/A4 amyloid precursor protein.

1992 • 202 citations

Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate.

1989 • 196 citations

Circular-dichroism studies on two murine serum amyloid A proteins

1988 • 168 citations

Localization of heparan sulfate glycosaminoglycan and proteoglycan core protein in aged brain and Alzheimer's disease

1992 • 161 citations

Immunolocalization of heparan sulfate proteoglycans to the prion protein amyloid plaques of Gerstmann-Straussler syndrome, Creutzfeldt-Jakob disease and scrapie.

1990 • 159 citations

Alzheimer's disease: amyloid plaques in the cerebellum

1989 • 150 citations

Diffuse type of senile plaques in the cerebellum of Alzheimer-type dementia demonstrated by? protein immunostain

1989 • 139 citations

Microangiopathy and the colocalization of heparan sulfate proteoglycan with amyloid in senile plaques of Alzheimer's disease

1990 • 128 citations

Evidence for lysosomal processing of amyloid ?-protein precursor in cultured cells

1989 • 114 citations

Heparan sulfate proteoglycan and laminin immunoreactivity on cultured astrocytes: relationship to differentiation and neurite growth

1988 • 114 citations

Acute phase proteins are present in amorphous plaques in the cerebral but not in the cerebellar cortex of patients with Alzheimer's disease

1990 • 99 citations

Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders

1991 • 89 citations

Soluble derivatives of the β amyloid protein precursor of Alzheimer's disease are labeled by antisera to the β amyloid protein

1989 • 85 citations

Basement membrane proteoglycan in various tissues: characterization using monoclonal antibodies to the Engelbreth-Holm-Swarm mouse tumor low density heparan sulfate proteoglycan.

1988 • 79 citations

Sulfated glycosaminoglycans modify growth factor‐induced neurite outgrowth in PC12 cells

1988 • 76 citations

The ultrastructural localization of sulfated proteoglycans is identical in the amyloids of Alzheimer's disease and AA, AL, senile cardiac and medullary carcinoma-associated amyloidosis

1989 • 75 citations

Ultrastructure of diffuse plaques in senile dementia of the Alzheimer type: comparison with primitive plaques

1991 • 72 citations

Immunoelectron microscopic localization of amyloid β protein in the diffuse plaques of Alzheimer-type dementia

1990 • 69 citations

Cationic dyes reveal proteoglycans structurally integrated within the characteristic lesions of Alzheimer's disease

1989 • 67 citations

Alpha 1-antichymotrypsin is present in diffuse senile plaques. A comparative study of beta-protein and alpha 1-antichymotrypsin immunostaining in the Alzheimer brain.

1991 • 65 citations

Functional interactions of neuronal heparan sulphate proteoglycans with laminin

1990 • 63 citations

Amyloid P component and other acute-phase proteins associated with cerebellar Aβ-deposits in Alzheimer's disease

1993 • 47 citations

The Amyloid P‐Component (Protein AP): an Integral Part of the Amyloid Substance?

1979 • 43 citations

Effects of nerve growth factor-induced differentiation on the heparan sulfate of PC12 pheochromocytoma cells and comparison with developing brain

1987 • 34 citations

Formic acid treatment exposes hidden neurofilament and tau epitopes in abnormal cytoskeletal filaments from patients with progressive supranuclear palsy and Alzheimer's disease

1990 • 31 citations

Nomenclature of amyloid and amyloidosis. WHO-IUIS Nomenclature Sub-Committee.

1993 • 25 citations

"Critical electrolyte concentration" method in histochemistry.

1969 • 16 citations

Nomenclature of amyloid A4 proteins and their precursors in Alzheimer's disease and down's syndrome

1990 • 13 citations

Changes in Glycosaminoglycans During the Neuritogenesis in PC12 Pheochromocytoma Cells Induced by Nerve Growth Factor

1990 • 13 citations

Reconstituted basement membrane enhances neurite outgrowth in PC12 cells induced by nerve growth factor.

1990 • 9 citations