Plk Is a Functional Homolog of Saccharomyces cerevisiae Cdc5, and Elevated Plk Activity Induces Multiple Septation Structures

Methods in yeast genetics

1979 • 7,824 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

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1988 • 4,905 citations

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

1988 • 2,903 citations

Distinct Roles for Cyclin-Dependent Kinases in Cell Cycle Control

1993 • 1,096 citations

Origins of Cell Polarity

1996 • 1,024 citations

The Primary Structure of MEK, a Protein Kinase that Phosphorylates the ERK Gene Product

1992 • 931 citations

Coordination of growth with cell division in the yeast

1977 • 848 citations

Polo, a mitotic mutant of Drosophila displaying abnormal spindle poles

1988 • 546 citations

Purification and Molecular Cloning of Plx1, a Cdc25-Regulatory Kinase from Xenopus Egg Extracts

1996 • 506 citations

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae

1991 • 463 citations

Functionally homologous cell cycle control genes in budding and fission yeast

1982 • 410 citations

polo encodes a protein kinase homolog required for mitosis in Drosophila.

1991 • 403 citations

The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells.

1995 • 376 citations

Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: localization of the CDC3 gene product and the timing of events at the budding site.

1991 • 342 citations

Induction and down-regulation of PLK, a humanserine/threonine kinase expressed in proliferating cells andtumors.

1994 • 278 citations

Conservation of mitotic controls in fission and budding yeasts

1989 • 275 citations

Cell cycle analysis and chromosomal localization of human Plk1, a putative homologue of the mitotic kinases Drosophila polo and Saccharomyces cerevisiae Cdc5

1994 • 275 citations

Immunofluorescence localization of the Saccharomyces cerevisiae CDC12 gene product to the vicinity of the 10-nm filaments in the mother-bud neck.

1987 • 273 citations

[52] Staining of bud scars and other cell wall chitin with Calcofluor

1991 • 272 citations

A multicopy suppressor gene of the Saccharomyces cerevisiae G1 cell cycle mutant gene dbf4 encodes a protein kinase and is identified as CDC5.

1993 • 270 citations

Plk Is an M-Phase-Specific Protein Kinase and Interacts with a Kinesin-Like Protein, CHO1/MKLP-1

1995 • 266 citations

Transcription and regulatory signals at the mating type locus in yeast

1984 • 256 citations

A bifunctional gene product involved in two phases of the yeast cell cycle

1982 • 225 citations

Identification by Targeted Differential Display of an Immediate Early Gene Encoding a Putative Serine/Threonine Kinase

1995 • 196 citations

A template for the protein kinase family

1993 • 196 citations

Identification of an Early-Growth-Response Gene Encoding a Novel Putative Protein Kinase

1992 • 187 citations

Polo-like Kinase Is a Cell Cycle-regulated Kinase Activated during Mitosis

1995 • 165 citations

Identification and cloning of a protein kinase-encoding mouse gene, Plk, related to the polo gene of Drosophila.

1993 • 158 citations

prk, a Cytokine-inducible Human Protein Serine/Threonine Kinase Whose Expression Appears to be Down-regulated in Lung Carcinomas

1996 • 148 citations

Constitutive activation of Mek1 by mutation of serine phosphorylation sites.

1994 • 145 citations

A conserved mitotic kinase active at late anaphase—telophase in syncytial Drosophila embryos

1993 • 128 citations

Cloning and characterization of human and murine homologues of the Drosophila polo serine-threonine kinase.

1994 • 116 citations

Sak, a murine protein-serine/threonine kinase that is related to the Drosophila polo kinase and involved in cell proliferation.

1994 • 100 citations

Immunofluorescence Localization of the Saccharomyces cerevisiae CDC12 Gene Product to the Vicinity of the 10-nm Filaments in the Mother-Bud Neck

1987 • 95 citations

A Novel Role for Cdc5p in DNA Replication

1996 • 94 citations

Septin Scaffolds and Cleavage Planes in Saccharomyces

1996 • 86 citations

Cell Cycle- and Terminal Differentiation-Associated Regulation of the Mouse mRNA Encoding a Conserved Mitotic Protein Kinase

1993 • 86 citations

Chitin synthesis and localization in cell division cycle mutants of Saccharomyces cerevisiae.

1983 • 85 citations

A Multicopy Suppressor Gene of the Saccharomyces cerevisiae G₁ Cell Cycle Mutant Gene dbf4 Encodes a Protein Kinase and Is Identified as CDC5

1993 • 84 citations

Dominant negative protein kinase mutations that confer a G1 arrest phenotype.

1988 • 73 citations

Formation of septum-like structures at locations remote from the budding sites in cytokinesis-defective mutants of Saccharomyces cerevisiae

1985 • 34 citations