Antizyme, a protein induced by polyamines, accelerates the degradation of ornithine decarboxylase in Chinese-hamster ovary-cell extracts

POLYAMINES

1984 • 2,996 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures

1976 • 265 citations

The regulation and function of ornithine decarboxylase and of the polyamines.

1979 • 247 citations

Prevention of Rapid Intracellular Degradation of ODC by a Carboxyl-Terminal Truncation

1989 • 247 citations

ATP serves two distinct roles in protein degradation in reticulocytes, one requiring and one independent of ubiquitin.

1983 • 162 citations

Trypanosome ornithine decarboxylase is stable because it lacks sequences found in the carboxyl terminus of the mouse enzyme which target the latter for intracellular degradation.

1990 • 145 citations

Control of ornithine decarboxylase in Chinese hamster ovary cells by polyamines. Translational inhibition of synthesis and acceleration of degradation of the enzyme by putrescine, spermidine, and spermine.

1986 • 141 citations

Degradation of Ornithine Decarboxylase in Reticulocyte Lysate Is ATP-dependent but Ubiquitin-independent

1989 • 139 citations

Role of antizyme in degradation of ornithine decarboxylase in HTC cells

1985 • 127 citations

The C terminus of mouse ornithine decarboxylase confers rapid degradation on dihydrofolate reductase. Support for the pest hypothesis

1991 • 104 citations

Accumulation of ornithine decarboxylase-antizyme complex in HMOA cells

1985 • 100 citations

Ornithine Decarboxylase: Biology, Enzymology and Molecular Genetics

1990 • 95 citations

Degradation of ornithine decarboxylase in mammalian cells is ATP dependent but ubiquitin independent

1989 • 93 citations

Two distinct mechanisms for ornithine decarboxylase regulation by polyamines in rat hepatoma cells

1979 • 90 citations

Analyses of Ornithine Decarboxylase Antizyme mRNA with a cDNA Cloned from Rat Liver1

1990 • 88 citations

Effect of 1,3-diaminopropane on ornithine decarboxylase enzyme protein in thioacetamide-treated rat liver

1983 • 78 citations

Spermidine mediates degradation of ornithine decarboxylase by a non‐lysosomal, ubiquitin‐independent mechanism

1987 • 69 citations

Posttranscriptional regulation of ornithine decarboxylase activity

1986 • 64 citations

Identification of residues in ornithine decarboxylase essential for enzymic activity and for rapid protein turnover

1991 • 63 citations

Characterization of sequences involved in mediating degradation of ornithine decarboxylase in cells and in reticulocyte lysate

1991 • 57 citations

Ornithine decarboxylase inactivation in HeLa cells

1976 • 49 citations

Effects of putrescine on synthesis and degradation of ornithine decarboxylase in primary cultured hepatocytes

1986 • 49 citations

Ornithine decarboxylase antizyme in kidneys of male and female mice

1988 • 44 citations

Dicyclohexylamine effects on HTC cell polyamine content and ornithine decarboxylase activity

1985 • 43 citations

Chinese hamster ovary cells resistant to alpha-difluoromethylornithine are overproducers of ornithine decarboxylase.

1983 • 40 citations

Involvement of antizyme in stabilization of ornithine decarboxylase caused by inhibitors of polyamine synthesis

1989 • 28 citations

Two-Step Purification of Mouse Kidney Ornithine Decarboxylase

1988 • 23 citations

Stabilization of ornithine decarboxylase in erythroleukemia cells depleted of ATP

1989 • 9 citations

Effect of ATP depletion and phenanthroline on the spermidine-mediated decay of ornithine decarboxylase in erythroleukemia cells

1990 • 4 citations