Somatomedins/insulin-like growth factors, their receptors and binding proteins are present during mouse embryogenesis

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Tissue concentrations of somatomedin C: further evidence for multiple sites of synthesis and paracrine or autocrine mechanisms of action.

1984 • 1,171 citations

Differentiation of clonal lines of teratocarcinoma cells: formation of embryoid bodies in vitro.

1975 • 710 citations

The subunit structures of two distinct receptors for insulin-like growth factors I and II and their relationship to the insulin receptor.

1982 • 709 citations

Alkaline Phosphatase Activity in Mouse Teratoma

1973 • 630 citations

Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues.

1986 • 531 citations

Increased levels of multiplication-stimulating activity, an insulin-like growth factor, in fetal rat serum.

1980 • 313 citations

Cultured fibroblast monolayers secrete a protein that alters the cellular binding of somatomedin-C/insulinlike growth factor I.

1986 • 231 citations

Inhibition of biological activity of multiplication-stimulating activity by binding to its carrier protein.

1980 • 212 citations

Structural similarities between human receptors for somatomedin C and insulin: analysis by affinity labeling

1981 • 187 citations

EVIDENCE FROM RADIOLIGAND ASSAYS THAT SOMATOMEDIN-C AND INSULIN-LIKE GROWTH FACTOR-I ARE SIMILAR TO EACH OTHER AND DIFFERENT FROM OTHER SOMATOMEDINS1

1980 • 157 citations

Structural and functional homologies in the receptors for insulin and the insulin-like growth factors

1982 • 154 citations

Regulation of amphibian oocyte maturation

1985 • 148 citations

Epidermal growth factor receptors increase during the differentiation of embryonal carcinoma cells

1979 • 137 citations

Relation of Kidney Tissue Somatomedin-C/Insulin-Like Growth Factor I to Postnephrectomy Renal Growth in the Rat*

1985 • 135 citations

FETAL GROWTH CONTROL: THE ROLE OF INSULIN AND RELATED PEPTIDES

1984 • 129 citations

Isolation of a Somatomedin-Binding Protein from Preterm Amniotic Fluid. Development of a Radioimmunoassay*

1984 • 127 citations

Partial Characterization of a Somatomedin-Like Peptide from the Medium of Cultured Rat Sertoli Cells*

1987 • 117 citations

Ontogeny of Receptors for Insulin-Like Peptides in Chick Embryo Tissues: Early Dominance of Insulin-Like Growth Factor over Insulin Receptors in Brain*

1985 • 116 citations

Affinity-labeled plasma somatomedin-C/insulinlike growth factor I binding proteins. Evidence of growth hormone dependence and subunit structure.

1985 • 113 citations

Characterization of somatomedin/insulin-like growth factor receptors and correlation with biologic action in cultured neonatal rat astroglial cells

1987 • 107 citations

Insulin-like growth factor II binding to the type I somatomedin receptor. Evidence for two high affinity binding sites.

1986 • 104 citations

Tissue and Plasma Somatomedin-C/Insulin-Like Growth Factor I Concentrations in the Human Fetus during the First Half of Gestation

1986 • 102 citations

Insulin-Like Growth Factor Carrier Proteins in Neonatal and Adult Rat Serum Are Immunologically Different: Demonstration Using a New Radioimmunoassay for the Carrier Protein from BRL-3A Rat Liver Cells

1986 • 96 citations

Clinics in Endocrinology and Metabolism

1983 • 62 citations

Affinity-Labeled Somatomedin-C Receptors and Binding Proteins from the Human Fetus*

1984 • 62 citations

Extrapancreatic insulin gene expression in the fetal rat.

1984 • 61 citations

Insulin promotes the growth of F9 embryonal carcinoma cells apparently by acting through its own receptor

1982 • 55 citations

Tissue and Serum Concentrations of Somatomedin-C/Insulin-Like Growth Factor I in Fetal Rats Made Growth Retarded by Uterine Artery Ligation

1986 • 55 citations

Stage-specific insulin binding in mouse preimplantation embryos

1986 • 53 citations

Appearance of functional insulin receptors during the differentiation of embryonal carcinoma cells.

1981 • 51 citations

Developmentally regulated expression of insulin-like growth factors by differentiated murine teratocarcinomas and extraembryonic mesoderm

1986 • 49 citations

Expression of EGF receptor and transferrin by F9 and PC13 teratocarcinoma cells

1984 • 41 citations

Affinity Labeled Somatomedin-C-Binding Proteins in Rat Sera*

1984 • 41 citations

Insulin-Like Growth Factor Receptors in Rat Placental Membranes*

1984 • 39 citations

Production of insulin‐like growth factor‐II (MSA) by endoderm‐like cells derived from embryonal carcinoma cells: Possible mediator of embryonic cell growth

1985 • 39 citations

Serum‐free culture of PC13 murine embryonal carcinoma cells

1983 • 38 citations

Insulin Gene Expression in the Developing Rat Pancreas

1983 • 28 citations

Size Discrepancy Between Somatomedin-C and Insulin Receptors*

1984 • 25 citations

Insulin Receptors in Embryo and Extra Embryonic Membranes of Early Somite Rat Conceptus

1986 • 17 citations

Uptake and distribution of exogenous serum proteins in the cultured rat embryo

1984 • 15 citations

Ontogeny and Characterization of Basic Somatomedin Receptors in Rat Placenta*

1985 • 12 citations