Efficient transcription of a Caenorhabditis elegans heat shock gene pair in mouse fibroblasts is dependent on multiple promoter elements which can function bidirectionally.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Rapid transfer of DNA from agarose gels to nylon membranes

1985 • 1,810 citations

Transcriptional Control Signals of a Eukaryotic Protein-Coding Gene

1982 • 1,406 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Heat shock, from bacteria to man

1982 • 1,260 citations

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

1982 • 1,038 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

The Heat Shock Respons

1985 • 809 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

A drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene

1984 • 534 citations

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

1984 • 474 citations

Negatively supercoiled simian virus 40 DNA contains Z-DNA segments within transcriptional enhancer sequences

1983 • 474 citations

Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product

1985 • 402 citations

The primary structure and genetic organization of the bovine papillomavirus type 1 genome

1982 • 374 citations

Accumulation of a specific subset of D. melanogaster heat shock mRNAs in normal development without heat shock

1983 • 365 citations

A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene.

1982 • 333 citations

Activating protein factor binds in vitro to upstream control sequences in heat shock gene chromatin

1984 • 329 citations

Human HSP70 promoter contains at least two distinct regulatory domains.

1986 • 326 citations

Sequences required for in vitro transcriptional activation of a Drosophila hsp 70 gene

1985 • 291 citations

Changes in Eukaryotic Gene Expression in Response to Environmental Stress

1985 • 289 citations

Activation of heat-shock genes in eukaryotes

1985 • 263 citations

Transcription of the human hsp70 gene is induced by serum stimulation.

1985 • 235 citations

Transformation and replication in mouse cells of a bovine papillomavirus--pML2 plasmid vector that can be rescued in bacteria.

1982 • 226 citations

Characterization of the Bovine Papilloma virus plasmid maintenance sequences

1984 • 224 citations

Upstream elements necessary for optimal function of the hsp 70 promoter in transformed flies

1984 • 213 citations

Integration, transcription, and control of a Drosophila heat shock gene in mouse cells.

1981 • 212 citations

Nucleotide sequence analysis of the Drosophila small heat shock gene cluster at locus 67B

1983 • 198 citations

Sequence homologies in the 5' regions of four Drosophila heat-shock genes.

1981 • 188 citations

Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.

1982 • 180 citations

Bovine papilloma virus contains an activator of gene expression at the distal end of the early transcription unit.

1983 • 176 citations

Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors

1985 • 175 citations

Regulation of heat-shock genes: a DNA sequence upstream of Drosophila hsp70 genes is essential for their induction in monkey cells.

1982 • 171 citations

Isolation and functional analysis of a human 70,000-dalton heat shock protein gene segment.

1985 • 164 citations

Ecdysterone induces the transcription of four heat-shock genes in Drosophila S3 cells and imaginal discs

1982 • 160 citations

Separate regulatory elements for the heat-inducible and ovarian expression of the drosophila hsp26 gene

1985 • 138 citations

The DNA sequence analysis of soybean heat-shock genes and identification of possible regulatory promoter elements

1984 • 131 citations

Primary sequence of the 5′ flanking regions of the Drosophila heat shock genes in chromosome subdivision 67B

1981 • 115 citations

Transient and developmental activation of heat-shock genes

1985 • 114 citations

Locus Encoding a Family of Small Heat Shock Genes in Caenorhabditis elegans: Two Genes Duplicated to Form a 3.8-Kilobase Inverted Repeat

1985 • 110 citations

Localization of the hsp83 transcript within a 3292 nucleotide sequence from the 63B heat shock locus ofD. melanogaster

1983 • 106 citations

Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin.

1985 • 98 citations

Bovine Papilloma Virus Contains an Activator of Gene Expression at the Distal End of the Early Transcription Unit

1983 • 77 citations

The Heat Shock Consensus Sequence Is Not Sufficient for hsp70 Gene Expression in Drosophila melanogaster

1985 • 73 citations

Cloning and analysis of cDNA sequences coding for two 16 kllodalton heat shock proteins (hsps) inCaenorhabditis elegans:homology with the small hsps ofDrosophila

1983 • 72 citations

Steroid and high-temperature induction of the small heat-shock protein genes in Drosophila

1984 • 68 citations

Z-DNA in the rat somatostatin gene.

1985 • 66 citations

Locus encoding a family of small heat shock genes in Caenorhabditis elegans: two genes duplicated to form a 3.8-kilobase inverted repeat.

1985 • 61 citations

A bovine papilloma virus vector with a dominant resistance marker replicates extrachromosomally in mouse and E. coli cells.

1983 • 56 citations

Expression ofDrosophilaheat shock genes is regulated in Rat-1 cells

1982 • 53 citations

Transcription of Drosophila small hsp-tk hybrid genes is induced by heat shock and by ecdysterone in transfected Drosophila cells.

1985 • 38 citations

Nucleotide sequences responsible for the thermal inducibility of the Drosophila small heat-shock protein genes in monkey COS cells

1985 • 38 citations

Isolation of episomal bovine papillomavirus chromatin and identification of a DNase I-hypersensitive region

1983 • 37 citations

Repetitive Dictyostelium heat-shock promotor functions in Saccharomyces cerevisiae.

1984 • 27 citations

Structure of bovine papillomavirus type 1 DNA in a transformed mouse cell line

1986 • 26 citations

Identification of a sequence element in the promoter of the Drosophila melanogaster hsp23 gene that is required for its heat activation.

1985 • 26 citations

Physical state, expression and regulation of two glucocorticoid-controlled genes on bovine papilloma virus vectors

1986 • 15 citations

Enhancer-dependent expression of the rat preproinsulin gene in bovine papillomavirus type 1 vectors.

1985 • 14 citations