Factors which disorganize microtubules or microfilaments increase the frequency of cell transformation by polyoma virus

Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals.

1975 • 3,362 citations

Microfilaments in Cellular and Developmental Processes

1971 • 1,563 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

The Genome of Simian Virus 40

1978 • 948 citations

Tumorigenicity of virus-transformed cells in nude mice is correlated specifically with anchorage independent growth in vitro.

1975 • 747 citations

Microtubules

1973 • 603 citations

THE VINCA ALKALOIDS: A NEW CLASS OF ONCOLYTIC AGENTS.

1963 • 558 citations

A New, Quantitative, Approach to the Study of the Stages of Chemical Carcinogenesis in the Mouse's Skin

1947 • 532 citations

Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2-acetylaminofluorene.

1971 • 412 citations

Two-stage chemical oncogenesis in cultures of C3H/10T1/2 cells.

1976 • 294 citations

Tumour promoter induces anchorage independence irreversibly

1979 • 285 citations

Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells

1978 • 284 citations

A nonselective analysis of SV40 transformation of mouse 3T3 cells

1974 • 261 citations

THE INITIATING AND PROMOTING ELEMENTS IN TUMOR PRODUCTION

1944 • 251 citations

STEPS IN THE NEOPLASTIC TRANSFORMATION OF HAMSTER EMBRYO CELLS BY POLYOMA VIRUS

1963 • 243 citations

Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus

1977 • 211 citations

Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis.

1978 • 206 citations

Induction of cell division in medium lacking serum growth factor by SV40

1971 • 185 citations

Antileukemic Principles Isolated from Euphorbiaceae Plants

1976 • 178 citations

The nucleotide sequence and genome organization of the polyoma early region: Extensive nucleotide and amino acid homology with SV40

1979 • 162 citations

Griseofulvin interacts with microtubules both in vivo and in vitro

1976 • 161 citations

Abortive Transformation by Polyoma Virus

1968 • 156 citations

Tumor promoters induce changes in the chick embryo fibroblast cytoskeleton

1979 • 138 citations

Effect of route of administration and effusions on methotrexate pharmacokinetics.

1974 • 124 citations

Effect of tumor promoters, protease inhibitors, and repair processes on x-ray-induced sister chromatid exchanges in mouse cells.

1979 • 104 citations

Effect of phorbol myristate acetate on the recovery of spontaneous and ultraviolet light-induced 6-thioguanine and ouabain-resistant Chinese hamster cells.

1977 • 97 citations

Mezerein: Antileukemic Principle Isolated from Daphne mezereum L.

1975 • 97 citations

Epidermal growth factor enhancement of skin tumor induction in mice

1976 • 96 citations

Early Chromosomal Changes in SV<sub>40</sub>-Infected Human Fibroblast Cultures

1964 • 95 citations

Cellular alterations dependent upon the polyoma virus hr-t function: Separation of mitogenic from transforming capacities

1978 • 93 citations

Simian virus 40 small-t protein is required for loss of actin cable networks in rat cells

1980 • 80 citations

Simian virus 40 small t antigen is not required for the maintenance of transformation but may act as a promoter (cocarcinogen) during establishment of transformation in resting rat cells

1979 • 76 citations

Effect of X-Irradiation on Susceptibility of Cells to Transformation by Polyoma Virus

1963 • 68 citations

Effect of Cytoskeleton-Disrupting Agents on the Metastatic Behavior of Melanoma Cells<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1980 • 65 citations

Radiation Enhancement of SV40 Transformation in 3T3 and Human Cells

1968 • 65 citations

Melittin shares certain cellular effects with phorbol ester tumour promoters

1979 • 59 citations

Enhancement by thymidine analogs of susceptibility of cells to transformation by SV40

1964 • 57 citations

The effect of a tumor promoter, 12-O-tetradecanoyl-phorbol-13-acetate (TPA), on sister-chromatid exchange formation in cultured Chinese hamster cells

1979 • 56 citations

Growth state of the cell early after infection with simian virus 40 determines whether the maintenance of transformation will be A-gene dependent or independent

1979 • 54 citations

Effects of a new antitumor agent, epipodophyllotoxin, on growth and chromosomes in human hematopoietic cell lines.

1973 • 53 citations

X-ray observations of the 5 March 1979 γ-burst field

1979 • 47 citations

Detection and Quantitation of Simian Virus 40 Genetic Material in Abortively Transformed BALB/3T3 Clones

1972 • 46 citations

Conditions leading to the establishment of the N (a gene dependent) and A (a gene independent) transformed states after polyoma virus infection of rat fibroblasts

1978 • 44 citations

Mutagenesis by simian virus 40. I. Detection of mutations in Chinese hamster cell lines using different resistance markers

1976 • 41 citations

Griseofulvin: A potential agent of chromosomal segregation in cultured cells

1974 • 41 citations

SV40-induced Somatic Mutations: Possible Relevance to Viral Transformation

1980 • 37 citations

Direct Isolation and Characterization of “Flat” SV40-transformed Cells

1971 • 34 citations

Enhancement of simian virus 40 transformation and integration by 4-nitroquinoline 1-oxide.

1974 • 33 citations

General Polyploid produced by Cytochalasin B

1973 • 28 citations

Polyoma virus. The early region and its T-antigens

1979 • 28 citations

Chromosomal aberrations of don lung cells of Chinese hamster after exposure to vinblastine in vitro

1979 • 25 citations

Oral griseofulvin: a cocarcinogenic agent to methylcholanthrene induced cutaneous tumors.

1962 • 25 citations

Polyoma virus middle t antigen: a tumor progression factor

1980 • 17 citations

Factors affecting the frequency of transformation of rat embryo cells by simian virus 40

1979 • 16 citations

Colcemid-induced polyploidy and aneuploidy in normal and tumour cellsin vitro

1975 • 15 citations

DNA of simian virus 40 mutates Chinese hamster cells

1980 • 13 citations

The inhibitory effect of griseofulvin on the "promotion" of skin carcinogenesis.

1968 • 10 citations

Dissociation of the mitotic spindle in oocytes exposed to griseofulvin and vinblastine

1976 • 10 citations

Antitumor activity in Pimelia simplex.

1975 • 4 citations