Cannabis: Pharmacology and Interpretation of Effects

Constituents of Cannabis sativa L. XVII. A Review of the Natural Constituents

1980 • 566 citations

Marihuana Chemistry

1970 • 479 citations

Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking

1980 • 459 citations

Chemical Basis of Hashish Activity

1970 • 332 citations

Cannabidiol interferes with the effects of Δ9-tetrahydrocannabinol in man

1974 • 295 citations

Pharmacology of Marijuana

1975 • 283 citations

Physicochemical Properties, Solubility, and Protein Binding of Δ9 -Tetrahydrocannabinol

1974 • 212 citations

Marihuana: Studies on the Disposition and Metabolism of Delta-9-Tetrahydrocannabinol in Man

1970 • 205 citations

Tolerance and disposition of tetrahydrocannabinol in man.

1980 • 200 citations

Do Plasma Concentrations of Δ⁹‐Tetrahydrocannabinol Reflect the Degree of Intoxication?

1981 • 158 citations

Activity of Δ ⁸ - and Δ ⁹ -Tetrahydrocannabinol and Related Compounds in the Mouse

1971 • 158 citations

A comparison of the pharmacological activity in man of intravenously administered 1368-11368-11368-1, cannabinol, and cannabidiol

1973 • 156 citations

Mississippi-Grown Cannabis sativa L.: Preliminary Observation on Chemical Definition of Phenotype and Variations in Tetrahydrocannabinol Content versus Age, Sex, and Plant Part

1971 • 156 citations

The Metabolism of Δ⁹‐Tetrahydrocannabinol and Related Cannabinoids in Man

1981 • 154 citations

Clinical effects and plasma levels of ?9-Tetrahydrocannabinol (?9-THC) in heavy and light users of cannabis

1981 • 148 citations

Recent Advances in the Chemistry of Hashish

1967 • 147 citations

Comparison of effects of marihuana cigarettes of three different potencies

1982 • 142 citations

Intravenous Injection in Man of Δ ⁹ -Tetrahydrocannabinol and 11-OH-Δ ⁹ -Tetrahydrocannabinol

1972 • 126 citations

Structure-Activity Relationships in Man of Cannabis Constituents, and Homologs and Metabolites of Δ<sup>9</sup>-Tetrahydrocannabinol

1974 • 126 citations

Common cannabinoid phenotypes in 350 stocks of Cannabis.

1973 • 125 citations

Influence of cannabidiol on delta‐9‐tetrahydrocannabinol effects

1976 • 121 citations

Comparative effects of smoking marihuana or placebo on human motor and mental performance

1970 • 121 citations

Interactions ofΔ 11-tetrahydrocannabinol with cannabinol and cannabidiol following oral administration in man. Assay of cannabinol and cannabidiol by mass fragmentographywith cannabinol and cannabidiol following oral administration in man. Assay of cannabinol and cannabidiol by mass fragmentography

1981 • 118 citations

Cannabidiol and cannabinol in man

1973 • 117 citations

Single dose kinetics of deuterium labelled Δ1-tetrahydrocannabinol in heavy and light cannabis users

1982 • 116 citations

Forensic aspects of the metabolism and excretion of cannabinoids following oral ingestion of cannabis resin

1984 • 113 citations

Delta‐8‐ and delta‐9‐tetrahydrocannabinol; Comparison in man by oral and intravenous administration

1973 • 112 citations

Incidence and Toxicological Aspects of Drugs Detected in 484 Fatally Injured Drivers and Pedestrians in Ontario

1982 • 111 citations

Identification in human urine of Δ9-tetrahydrocannabinol-11-oic acid glucuronide: a tetrahydrocannabinol metabolite

1980 • 109 citations

Dose‐response analysis of the efJects of tetrahydrocannabinol in man

1971 • 107 citations

Binding of δ1-tetrahydrocannabinol to human plasma proteins

1970 • 106 citations

Marijuana and Driving in Real-Life Situations

1974 • 106 citations

Δ ¹ -Tetrahydrocannabinol: Structure of a Major Metabolite

1970 • 105 citations

Pharmacology of orally administered Δ⁹‐tetrahydrocannabinol

1973 • 102 citations

Isolation, structure, and biological activity of several metabolites of .DELTA.9/tetrahydrocannabinol

1970 • 95 citations

Relationship between plasma delta-9-tetrahydrocannabinol concentration and pharmacologic effects in man

1981 • 87 citations

Binding of (+)- and (-)-Δ1-tetrahydrocannabinols and (-)-7-hydroxy-Δ1-tetrahydrocannabinol to blood cells and plasma proteins in man

1974 • 85 citations

Interactions in man of delta‐9‐tetrahydrocannabinol; II. Cannabinol and cannabidiol

1975 • 84 citations

Persistence of urinary marijuana levels after supervised abstinence

1982 • 81 citations

Ethanol, Marijuana, and Other Drug Use in 600 Drivers Killed in Single-Vehicle Crashes in North Carolina, 1978–1981

1984 • 80 citations

HYDROXYLATION OF TRANS‐Δ¹‐TETRAHYDROCANNABINOL BY HEPATIC MICROSOMAL OXYGENASE*

1971 • 80 citations

Ethanol, marijuana, and other drug use in 600 drivers killed in single-vehicle crashes in North Carolina, 1978-1981.

1984 • 79 citations

Comparative Pharmacology of Δ9-Tetrahydrocannabinol and its Metabolite, 11-OH-Δ9-Tetrahydrocannabinol

1973 • 76 citations

Tolerance to marijuana: Heart rate and subjective “high”

1977 • 74 citations

Metabolite of (—)- trans -Δ ⁸ -Tetrahydrocannabinol: Identification and Synthesis

1970 • 71 citations

Passive inhalation of marihuana smoke and urinary excretion of cannabinoids

1983 • 70 citations

The Clinical Pharmacology and Dynamics of Marihuana Cigarette Smoking

1981 • 70 citations

THE IN VITRO AND IN VIVO METABOLISM OF TETRAHYDROCANNABINOL (THC) *

1971 • 70 citations

Interactions of several cannabinoids with the hepatic drug metabolizing system

1973 • 65 citations

EFFECTS OF CANNABIS AND ALCOHOL ON AUTOMOBILE DRIVING AND PSYCHOMOTOR TRACKING

1976 • 61 citations

Cannabis. V. Cannabigerolic Acid Monomethyl Ether and Cannabinolic Acid

1970 • 61 citations

125I radioimmunoassay of delta-9-tetrahydrocannabinol in blood and plasma with a solid-phase second-antibody separation method.

1981 • 59 citations

METABOLISM AND DISPOSITION OF TETRAHYDROCANNABINOLS IN NÄIVE SUBJECTS AND CHRONIC MARIJUANA USERS

1971 • 54 citations

Metabolism of Δ1(6)-Tetrahydro-cannabinol, an Active Marihuana Constituent

1970 • 52 citations

Interactions of Δ9-tetrahydrocannabinol with the hepatic microsomal drug metabolizing system

1971 • 49 citations

Analysis of Cannabis Smoke Obtained under Different Combustion Conditions

1972 • 46 citations

Constituents of cannabis sativa L. XVI. A possible decomposition pathway of Δ⁹‐tetrahydrocannabinol to cannabinol

1979 • 46 citations

Stability, transfer and absorption of cannabinoid constituents of cannabis (hashish) during smoking.

1971 • 45 citations

The content of (-)Δ9-trans-tetrahydrocannabinol (Δ9-THC) does not explain all biological activity of some Brazilian marihuana samples

1972 • 44 citations

Hashish VI1: Conversion of (-)-Δ 1(6)-Tetrahydrocannabinol to (-)-Δ 1(7)-Tetrahydrocannabinol. Stability of (-)-Δ 1 and (-)-Δ 1(6)-Tetrahydrocannabinols

1972 • 43 citations

Kinetic study of smoking marijuana

1982 • 43 citations

Marijuana and driving.

1981 • 42 citations

Comparison of 3H- and 125I-Radioimmunoassay and Gas Chromatography/Mass Spectrometry for the Determination of 9-Tetrahydrocannabinol and Cannabinoids in Blood and Serum

1983 • 41 citations

The non-specific membrane binding properties of ΔA9-tetrahydrocannabinol and the effects of various solubilizers

1979 • 41 citations

A comparison of the pharmacological activity ofgD 9-Tetrahydrocannabinol and its monohydroxylated metabolites in man

1973 • 41 citations

The cannabinoid content of Cannabis sativa L grown in England

1974 • 39 citations

Marihuana: effects on simulated driving performance†

1976 • 38 citations

Constituents of Cannabis sativa L. VI: Propyl Homologs in Samples of Known Geographical Origin

1973 • 38 citations

Identification of in vitro metabolites of delta 1-tetrahydrocannabinol formed by human livers.

1982 • 38 citations

Combined high-performance liquid chromatography and radioimmunoassay method for tha analysis of Δ9-tetrahydrocannabinol metabolites in human urine

1979 • 35 citations

Plasma concentrations of δ-9-tetrahydrocannabinol and impaired motor function

1983 • 34 citations

Marihuana Components: Effects of Smoking on Δ ⁹ -Tetrahydrocannabinol and Cannabidiol

1971 • 33 citations

Plasma and Brain Levels of Δ⁶‐THC and Seven Monooxygenated Metabolites Correlated to the Cataleptic Effect in the Mouse

1980 • 33 citations

The intracellular localization of Δ9-tetrahydrocannabinol in liver and its effects on drug metabolism in vitro

1973 • 33 citations

Identification of .DELTA.9-tetrahydrocannabinol and metabolites in man

1972 • 29 citations

Concerning the Isomerization of Δ¹-to Δ¹⁽⁶⁾-Tetrahydrocannabinol¹

1966 • 29 citations

The Use of Marihuana, Ethanol, and Other Drugs Among Drivers Killed in Single-Vehicle Crashes

1983 • 28 citations

The Incidence of Cannabinoids in Fatally Injured Drivers: An Investigation by Radioimmunoassay and High Pressure Liquid Chromatography

1977 • 27 citations

Cannabinoid Concentrations in Plasma After Passive Inhalation of Marijuana Smoke

1983 • 27 citations

Long-Term Use of Marihuana and the Development of Tolerance or Sensitivity toΔ9Tetrahydrocannabinol

1974 • 27 citations

Crystal and molecular structure of cannabispiran and its correlation to dehydrocannabispiran

1977 • 27 citations

Impairment of performance with low doses of marihuana

1973 • 26 citations

The use of zonal ultracentrifugation in the investigation of the binding of delta9-tetrahydrocannabinol by plasma lipoproteins.

1975 • 25 citations

Haschisch, XV¹⁾ Über das Verhalten von Hanf und von Δ⁹‐6a.10a‐trans‐Tetrahydrocannabinol beim Rauchen

1968 • 24 citations

Marihuana and driving†

1976 • 19 citations

An EMIT Assay for Cannabinoid Metabolites in Urine

1982 • 18 citations

An Evaluation of a Homogeneous Enzyme Immunoassay (EMIT) for Cannabinoid Detection in Biological Fluids

1982 • 17 citations

Urine Testing for Marijuana Use

1983 • 17 citations

Marijuana metabolites in urine of man

1982 • 15 citations

The free radical oxidation of the tetrahydrocannabinols

1982 • 15 citations

Radioimmunoassays for Cannabinoids

1982 • 15 citations

Microsomal oxygenase catalyzed oxidation of 11-hydroxy-Δ8-tetrahydrocannabinol to 11-oxo-Δ8-tetrahydrocannabinol

1979 • 15 citations

Marihuana metabolites in urine of man

1972 • 14 citations

A Comparative Analysis of Cannabis Material

1979 • 13 citations

Marihuana metabolites in the urine of man

1978 • 12 citations

Identification and determination of 11-oxo-.DELTA.8-tetrahydrocannabinol as an intermediate metabolite of .DELTA.8-tetrahydrocannabinol in the mouse brain and liver.

1980 • 10 citations

7-Oxo-delta1-tetrahydrocannabinol: a novel metabolite of delta1-tetrahydrocannabinol.

1974 • 9 citations

Recent Advances in the Chemistry and Metabolism of the Cannabinoids

1975 • 9 citations

Quantitation of Δ⁹-Tetrahydrocannabinol and Its Metabolites in Human Urine by Probability Based Matching GC/MS

1979 • 8 citations

Glucuronic acid conjugate of delta 1-tetrahydrocannabinol identified in the urine of man.

1983 • 6 citations

Marihuana metabolites in urine of man. III. Unchanged delta-9-tetrahydrocannabinol.

1974 • 6 citations

Detection and Quantitation of Tetrahydrocannabinol in Physiological Fluids

1979 • 6 citations

The Analysis of Cannabinoids in Biological Fluids: NIDA Research Monograph 42

1982 • 6 citations

Significant Developments in Radioimmune Methods Applied to Delta 9 THC and its 9-Substituted Metabolites

1982 • 5 citations

Quantitative Analysis for Delta 9 THC, 11-Hydroxy-Delta 9-THC, and 9-Carboxy-Delta 9-THC in Plasma Using GC/CI-MS

1982 • 5 citations

THE EFFECTS OF MODERATE LEVELS OF ALCOHOL AND MARIHUANA, ALONE AND IN COMBINATION ON CLOSED-COURSE DRIVING PERFORMANCE

1981 • 4 citations

Detection of marihuana use by GC/MS analysis of mouth swabs

1983 • 2 citations