Relationship between plasma delta-9-tetrahydrocannabinol concentration and pharmacologic effects in man

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

1964 • 2,296 citations

Simultaneous modeling of pharmacokinetics and pharmacodynamics: Application to d‐tubocurarine

1979 • 1,136 citations

Calculus and Analytic Geometry

1985 • 706 citations

Clinical and Psychological Effects of Marihuana in Man

1968 • 483 citations

Plasma delta-9-tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking

1980 • 459 citations

Effects of (?)?9-trans-tetrahydrocannabinol in man

1967 • 396 citations

Pharmacology of Marihuana

1977 • 378 citations

Kinetics of pharmacologic response I. Proposed relationships between response and drug concentration in the intact animal and man

1968 • 303 citations

CLINICAL STUDIES OF CANNABIS TOLERANCE AND DEPENDENCE*

1976 • 269 citations

Calculus and Analytic Geometry.

1970 • 249 citations

Marihuana: Studies on the Disposition and Metabolism of Delta-9-Tetrahydrocannabinol in Man

1970 • 205 citations

Tolerance and disposition of tetrahydrocannabinol in man.

1980 • 200 citations

Kinetics of pharmacologic effects

1966 • 195 citations

Relationship between the pharmacokinetics and pharmacodynamics of procainamide

1976 • 155 citations

Role of Pharmacokinetics in Drug Dosage Adjustment. I. Pharmacologic Effect Kinetics and Apparent Volume of Distribution of Digoxin

1973 • 149 citations

Some cardiovascular effects of marihuana smoking in normal volunteers

1971 • 146 citations

Psychological Effects of Tetrahydrocannabinol

1970 • 114 citations

Dose‐response analysis of the efJects of tetrahydrocannabinol in man

1971 • 107 citations

Pharmacology of orally administered Δ⁹‐tetrahydrocannabinol

1973 • 102 citations

Delta-9-Tetrahydrocannabinol

1972 • 97 citations

Cardiovascular effects of delta‐9‐tetrahydrocannabinol in man

1972 • 95 citations

The influence of alcohol and marihuana on motor and mental performance

1971 • 91 citations

Quantitative analysis of the disopyramide concentration‐effect relationship.

1980 • 76 citations

Tolerance to marijuana: Heart rate and subjective “high”

1977 • 74 citations

Pharmacodynamics of the antiarrhythmic disopyramide in healthy humans: Correlation of the kinetics of the drug and its effects

1976 • 69 citations

Pharmacokinetics of digoxin: Relationship between response intensity and predicted compartmental drug levels in man

1979 • 64 citations

Correlation of performance test scores with “tissue concentration” of lysergic acid diethylamide in human subiects

1968 • 64 citations

125I radioimmunoassay of delta-9-tetrahydrocannabinol in blood and plasma with a solid-phase second-antibody separation method.

1981 • 59 citations

Response optimization of drug dosage: Antiarrhythmie studies with tocainide

1977 • 54 citations

Comparative Bioavailabilities from Truncated Blood Level Curves

1975 • 51 citations

Modeling of drug response in individual subjects

1980 • 47 citations

Marijuana Consumption and Tolerance to Physiological and Subjective Effects

1975 • 43 citations

Marihuana and the cardiovascular system

1975 • 33 citations

Plasma concentrations and effects of methaqualone after single and multiple oral doses in man

1974 • 32 citations

Pharmacokinetics and Dynamics of Muscle Relaxants

1979 • 27 citations

Long-Term Use of Marihuana and the Development of Tolerance or Sensitivity toΔ9Tetrahydrocannabinol

1974 • 27 citations

Progress in Drug Research (Vol. 42)

1994 • 21 citations

Marijuana: Dose-Response Effects on Pulse Rate, Subjective Estimates of Potency, Pleasantness, and Recognition Memory

1977 • 18 citations

Pharmacokinetics of β-Methyldigoxin in Healthy Humans III: Pharmacodynamic Correlations

1977 • 17 citations

A mathematical model for the pharmacokinetics of LSD effect

1969 • 13 citations

Kinetics of pharmacologic response to cocaine.

1978 • 12 citations

Pharmacokinetics of LSD effect

1969 • 7 citations

The pharmacokinetic bases of biological response quantification in toxicology, pharmacology and pharmacodynamics

1977 • 5 citations

Physiological Assessments: Cardiopulmonary Function

1974 • 5 citations

Proceedings: Pharmacokinetics in relation to physiological and psychological effects of delta-8-THC.

1974 • 2 citations