Genomic Structure and Chromosomal Localization of a Humanmyo-Inositol Monophosphatase Gene (IMPA)

MANIC DEPRESSIVE ILLNESS

1984 • 3,013 citations

A molecular mechanism for the effect of lithium on development.

1996 • 2,270 citations

Lithium inhibits glycogen synthase kinase-3 activity and mimics Wingless signalling in intact cells

1996 • 1,299 citations

Neural and developmental actions of lithium: A unifying hypothesis

1989 • 1,005 citations

A gene map of the human genome.

1996 • 986 citations

Exhaustive Matching of the Entire Protein Sequence Database

1992 • 844 citations

A Gene Map of the Human Genome

1996 • 737 citations

Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene.

1994 • 378 citations

Modification of enzymatic-ally amplified DNA for the detection of point mutations

1989 • 330 citations

Signal Transduction Pathways

1995 • 328 citations

A manic depressive history

1996 • 211 citations

A complete genome screen for genes predisposing to severe bipolar disorder in two Costa Rican pedigrees

1996 • 175 citations

Chromosome 18 DNA markers and manic-depressive illness : evidence for a susceptibility gene

1994 • 169 citations

Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure.

1995 • 156 citations

The American Psychiatric Press Textbook of Psychopharmacology

1995 • 142 citations

Yeast transcriptional activatorINO2interacts as an Ino2p/Ino4p basic helix-loop-helix heteromeric complex with the inositol/choline-responsive element necessary for expression of phospholipid biosynthetic genes inSaccharomyces cerevisiae

1995 • 134 citations

Coordinate genetic control of yeast fatty acid synthase genes FAS1 and FAS2 by an upstream activation site common to genes involved in membrane lipid biosynthesis.

1992 • 128 citations

Mechanism of inositol monophosphatase, the putative target of lithium therapy.

1994 • 112 citations

Inositol monophosphatase — a putative target for Li+ in the treatment of bipolar disorder

1995 • 105 citations

cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme

1992 • 101 citations

Structural Studies of Metal Binding by Inositol Monophosphatase: Evidence for Two-Metal Ion Catalysis

1994 • 98 citations

Application of natural and amplification created restriction sites for the diagnosis of PKU mutations

1991 • 91 citations

Structural Analysis of Inositol Monophosphatase Complexes with Substrates

1994 • 89 citations

Structure and mechanism of inositol monophosphatase

1995 • 79 citations

Interaction oftransandcisregulatory elements in theINO1promoter ofSaccharomyces cerevisiae

1991 • 78 citations

Homologous unequal cross-over involving a 2.8 kb direct repeat as a mechanism for the generation of allelic variants of the human cytochrome P450 CYP2D6 gene

1995 • 73 citations

Human Fructose-1,6-Bisphosphatase Gene (FBP1): Exon-Intron Organization, Localization to Chromosome Bands 9q22.2-q22.3, and Mutation Screening in Subjects with Fructose-1,6-Bisphosphatase Deficiency

1995 • 73 citations

Gene–based sequence–tagged–sites (STSs) as the basis for a human gene map

1995 • 72 citations

DNA binding site of the yeast heteromeric Ino2p/Ino4p basic helix‐loop‐helix transcription factor: structural requirements as defined by saturation mutagenesis

1995 • 66 citations

The American Psychiatric Press Textbook of Psychopharmacology

1995 • 57 citations

Diverse proteins homologous to inositol monophosphatase

1991 • 48 citations

Structural Similarities between Fructose-1,6-bisphosphatase and Inositol Monophosphatase

1993 • 43 citations

Bipolar Disorder

1996 • 25 citations

Lack of genetic variation in the coding region of the myo-inositol monophosphatase gene in lithium-treated patients with manic depressive illness

1996 • 23 citations

Dictyostelium discoideum contains three inositol monophosphatase activities with different substrate specificities and sensitivities to lithium

1996 • 20 citations

Inositol-1-phosphatase of human erythrocytes is inhibited by therapeutic lithium concentrations

1989 • 19 citations