Impact of tumour necrosis factor-α and interferon-γ on tetrahydrobiopterin synthesis in murine fibroblasts and macrophages

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

Immune response-associated production of neopterin. Release from macrophages primarily under control of interferon-gamma.

1984 • 1,083 citations

Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose: Bio-blots.

1983 • 1,075 citations

A simple cytochemical technique for demonstration of DNA in cells infected with mycoplasmas and viruses

1975 • 788 citations

Analysis of reduced forms of biopterin in biological tissues and fluids

1980 • 713 citations

Macrophage Oxidation of L-Arginine to Nitric Oxide, Nitrite, and Nitrate

1989 • 681 citations

Reduced Biopterin as a Cofactor in the Generation of Nitrogen Oxides by Murine Macrophages

1989 • 571 citations

BIOSYNTHESIS AND METABOLISM OF TETRAHYDROBIOPTERIN AND MOLYBDOPTERIN

1985 • 542 citations

Nitric oxide: biosynthesis and biological significance

1989 • 421 citations

Neopterin as Marker for Activation of Cellular Immunity: Immunologic Basis and Clinical Application

1989 • 373 citations

Chemistry and biology of pteridines 1986

1987 • 335 citations

Tetrahydrobiopterin-dependent formation of nitrite and nitrate in murine fibroblasts.

1990 • 288 citations

Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1, and T 24 cells. GTP-cyclohydrolase I is stimulated by interferon-gamma, and 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present.

1990 • 239 citations

Effect of cloned interferon‐γ on expression of H‐2 and Ia antigens on cell lines of hemopoietic, lymphoid, epithelial, fibroblastic and neuronal origin

1984 • 192 citations

Bone marrow-derived macrophages: development and regulation of differentiation markers by colony-stimulating factor and interferons.

1985 • 182 citations

Characteristics of guanosine triphosphate cyclohydrolase I purified from Escherichia coli.

1976 • 153 citations

Biosynthesis and metabolism of pterins in peripheral blood mononuclear cells and leukemia lines of man and mouse

1987 • 130 citations

Biopterin cofactor biosynthesis: GTP cyclohydrolase, neopterin and biopterin in tissues and body fluids of mammalian species

1984 • 105 citations

Simultaneous determination of neopterin and creatinine in serum with solid-phase extraction and on-line elution liquid chromatography.

1987 • 102 citations

Interferon-γ Enhances Biosynthesis of Pterins in Peripheral Blood Mononuclear Cells by Induction of GTP-Cyclohydrolase I Activity

1986 • 78 citations

Control of tetrahydrobiopterin synthesis in T lymphocytes by synergistic action of interferon-gamma and interleukin-2.

1990 • 75 citations

[Increased urinary excretion of neopterin in patients with malignant tumors and with virus diseases (author's transl)].

1979 • 73 citations

Dependence of an alkyl glycol-ether monooxygenase activity upon tetrahydropterins

1990 • 43 citations

Different mechanisms for activation of gene transcription by interferons α and γ

1985 • 38 citations

Immunohistochemical localization of indoleamine 2,3-dioxygenase in the argyrophilic cells of rabbit duodenum and thyroid gland.

1981 • 29 citations

Isolation and characterization of GTP cyclohydrolase I from mouse liver. Comparison of normal and the hph-1 mutant

1991 • 27 citations

Enhanced urinary excretion of 7,8-dihydro-6-hydroxylumazine by mice bearing the ehrlich ascites tumour

1979 • 23 citations

Altered Urinary Excretion of Pteridines in Dogs with Various Tumours

1987 • 3 citations

Increased biopterin production in rats with tumors induced by radon inhalation and benzonaphtoflavone administration

1990 • 3 citations