Identification of a nuclear protein that constitutively recognizes the sequence containing a heat‐shock element

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

Firefly luciferase gene: structure and expression in mammalian cells.

1987 • 3,088 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

A new puffing pattern induced by temperature shock and DNP in drosophila

1962 • 1,969 citations

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

1968 • 1,767 citations

Microsomal Heme Oxygenase

1969 • 1,348 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

A regulatory upstream promoter element in the Drosophila Hsp 70 heat-shock gene

1982 • 1,038 citations

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

1990 • 993 citations

Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70.

1985 • 860 citations

Stress proteins in biology and medicine

1990 • 731 citations

Key features of heat shock regulatory elements.

1988 • 566 citations

Stress proteins in biology and medicine

1990 • 502 citations

Heat shock factor is regulated differently in yeast and HeLa cells

1987 • 489 citations

Molecular cloning and expression of a human heat shock factor, HSF1.

1991 • 472 citations

Germline Transformation Used to Define Key Features of Heat-Shock Response Elements

1988 • 451 citations

Cloning and expression of cDNA for rat heme oxygenase.

1985 • 451 citations

Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit

1989 • 439 citations

Transcriptional control of rat heme oxygenase by heat shock.

1987 • 415 citations

Coordinate changes in heat shock element-binding activity and HSP70 gene transcription rates in human cells.

1988 • 407 citations

The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin.

1970 • 396 citations

Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.

1991 • 381 citations

Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

1987 • 379 citations

Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans.

1991 • 347 citations

Human heme oxygenase cDNA and induction of its mRNA by hemin

1988 • 320 citations

Reduced nicotinamide adenine dinucleotide phosphate dependent biliverdin reductase. Partial purification and characterization

1970 • 264 citations

Cobalt Induction of Hepatic Heme Oxygenase; with Evidence That Cytochrome P -450 Is Not Essential for This Enzyme Activity

1974 • 261 citations

Cooperative binding of drosophila heat shock factor to arrays of a conserved 5 bp unit

1991 • 250 citations

Cloning and expression of cDNA encoding mouse tyrosinase

1986 • 241 citations

Heat-Inducible Human Factor That Binds to a Human hsp70 Promoter

1987 • 232 citations

Oxidant stress leads to transcriptional activation of the human heme oxygenase gene in cultured skin fibroblasts.

1990 • 226 citations

Nucleotide sequence and organization of the rat heme oxygenase gene.

1987 • 210 citations

Studies on the mechanism of induction of haem oxygenase by cobalt and other metal ions

1976 • 202 citations

The ets sequence from the transforming gene of avian erythroblastosis virus, E26, has unique domains on human chromosomes 11 and 21: both loci are transcriptionally active.

1985 • 177 citations

The human 32‐kDa stress protein induced by exposure to arsenite and cadmium ions is heme oxygenase

1989 • 163 citations

Heat shock-induced interactions of heat shock transcription factor and the human hsp70 promoter examined by in vivo footprinting.

1991 • 159 citations

Structural organization of the human heme oxygenase gene and the function of its promoter

1989 • 143 citations

Heat-inducible human factor that binds to a human hsp70 promoter.

1987 • 132 citations

Inducible heme oxygenase in the kidney: a model for the homeostatic control of hemoglobin catabolism

1971 • 131 citations

THE ENZYMATIC DEGRADATION OF HEMOGLOBIN TO BILE PIGMENTS BY MACROPHAGES

1971 • 130 citations

Maximal stress-induced transcription from the human HSP70 promoter requires interactions with the basal promoter elements independent of rotational alignment.

1990 • 127 citations

[Regulation of heme oxygenase gene expression].

1989 • 106 citations

Interaction of upstream stimulatory factor with the human heme oxygenase gene promoter

1990 • 62 citations

Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells

1989 • 54 citations

Transcriptional control of the rat heme oxygenase gene by a nuclear protein that interacts with adenovirus 2 major late promoter

1989 • 42 citations

Transcriptional regulation of a yeast HSP70 gene by heat shock factor and an upstream repression site-binding factor.

1991 • 24 citations