Drastic Up-Regulation of FcεRI on Mast Cells Is Induced by IgE Binding Through Stabilization and Accumulation of FcεRI on the Cell Surface

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

1991 • 1,783 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

Fc Receptors

1991 • 1,220 citations

THE HIGH-AFFINITY I<scp>g</scp>E RECEPTOR (FcεRI): From Physiology to Pathology

1999 • 949 citations

Augmented humoral and anaphylactic responses in FcγRII-deficient mice

1996 • 828 citations

Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody.

1997 • 817 citations

Signalling through the high-affinity IgE receptor FcεRI

1999 • 730 citations

Human IgE, IgG4 and resistance to reinfection with Schistosoma haematobium

1991 • 649 citations

The Receptor with High Affinity for Immunoglobulin E

1986 • 540 citations

The human IgE network

1993 • 504 citations

Human epidermal Langerhans cells express the high affinity receptor for immunoglobulin E (Fc epsilon RI).

1992 • 490 citations

IgE Enhances Mouse Mast Cell FcεRI Expression In Vitro and In Vivo: Evidence for a Novel Amplification Mechanism in IgE-dependent Reactions

1997 • 448 citations

Epidermal Langerhans cells from normal human skin bind monomeric IgE via Fc epsilon RI.

1992 • 388 citations

Signal transduction by Fc receptors: the Fc&amp;RI case

1993 • 373 citations

Activation of Mast Cells for Mediator Release through IgE Receptors

2015 • 369 citations

Mast Cells Can Secrete Vascular Permeability Factor/ Vascular Endothelial Cell Growth Factor and Exhibit Enhanced Release after Immunoglobulin E–dependent Upregulation of Fcε Receptor I Expression

1998 • 333 citations

Peripheral blood dendritic cells express Fc epsilon RI as a complex composed of Fc epsilon RI alpha- and Fc epsilon RI gamma-chains and can use this receptor for IgE-mediated allergen presentation.

1996 • 332 citations

Anaphylaxis

1991 • 320 citations

IgE receptors on human basophils. Relationship to serum IgE concentration.

1978 • 263 citations

Allergy-Associated FcRβ Is a Molecular Amplifier of IgE- and IgG-Mediated In Vivo Responses

1998 • 210 citations

Down-regulation of human basophil IgE and FC epsilon RI alpha surface densities and mediator release by anti-IgE-infusions is reversible in vitro and in vivo.

1999 • 209 citations

Thirteen hybridomas secreting hapten‐specific immunoglobulin E from mice with Ig^a or Ig^b heavy chain haplotype

1981 • 201 citations

Expression of High-affinity Binding of Human Immunoglobulin E by Transfected Cells

1989 • 194 citations

Down-Regulation of Human Basophil IgE and FCεRIα Surface Densities and Mediator Release by Anti-IgE-Infusions Is Reversible In Vitro and In Vivo

1999 • 169 citations

IgE regulates mouse basophil Fc epsilon RI expression in vivo.

1997 • 165 citations

Effect of recombinant human IL-4 on tryptase, chymase, and Fc epsilon receptor type I expression in recombinant human stem cell factor-dependent fetal liver-derived human mast cells.

1997 • 162 citations

Expression of high-affinity IgE receptors (FcϵRI) on peripheral blood basophils, monocytes, and eosinophils in atopic and nonatopic subjects: Relationship to total serum IgE concentrations

1997 • 150 citations

In Vitro Regulation of FcRIα Expression on Human Basophils by IgE Antibody

1998 • 144 citations

The receptor for immunoglobulin E on rat basophilic leukemia cells: effect of ligand binding on receptor expression.

1985 • 127 citations

In Vitro Regulation of FcRIα Expression on Human Basophils by IgE Antibody

1998 • 123 citations

Lymphokine and Cytokine Production by FcεRI+ Cells

1993 • 122 citations

IgE antibody up-regulates high affinity IgE binding on murine bone marrow-derived mast cells

1996 • 119 citations

Anaphylaxis mediated through a humanized high affinity IgE receptor.

1996 • 108 citations

Anaphylaxis mediated through a humanized high affinity IgE receptor.

1996 • 97 citations

The gene and cDNA for the human high affinity immunoglobulin E receptor beta chain and expression of the complete human receptor.

1992 • 94 citations

Production of macrophage inflammatory protein-1alpha by human mast cells: increased anti-IgE-dependent secretion after IgE-dependent enhancement of mast cell IgE-binding ability.

1997 • 83 citations

The Fate of IgE Bound to Rat Basophilic Leukemia Cells

1979 • 70 citations

Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor alpha chain respond to human IgE in mast cell degranulation and in allergic reactions.

1996 • 65 citations

Kinetics of the appearance of Fc epsilon RI-bearing cells in interleukin-3-dependent mouse bone marrow cultures: correlation with histamine content and mast cell maturation

1992 • 43 citations

Coordinate synthesis and degradation of the α-, β- and γ-subunits of the receptor for immunoglobulin E

1985 • 42 citations

Immunomorphologic Characterization of Fc∈RI-Bearing Cells Within the Human Dermis

1994 • 33 citations

Establishment of antigen-specific IgE transgenic mice to study pathological and immunobiological roles of IgE in vivo

1999 • 32 citations

Cell cycle and morphological changes during growth and differentiation of a rat basophilic leukemia cell line.

1976 • 19 citations

Deleted Work

1955 • 0 citations