Structure of a DNA-bound Ultrabithorax–Extradenticle homeodomain complex

[20] Processing of X-ray diffraction data collected in oscillation mode

1997 • 33,348 citations

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

A gene complex controlling segmentation in Drosophila

1978 • 3,668 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods

1997 • 1,905 citations

SETOR: Hardware-lighted three-dimensional solid model representations of macromolecules

1993 • 1,295 citations

Crystal structure of trp represser/operator complex at atomic resolution

1988 • 899 citations

HOMEODOMAIN PROTEINS

1994 • 828 citations

Surface, subunit interfaces and interior of oligomeric proteins

1988 • 644 citations

Recognition of a DNA Operator by the Repressor of Phage 434: A View at High Resolution

1988 • 531 citations

Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins

1996 • 393 citations

The DNA binding specificity of ultrabithorax is modulated by cooperative interactions with extradenticle, another homeoprotein

1994 • 378 citations

Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.

1991 • 344 citations

Pbx Modulation of Hox Homeodomain Amino-Terminal Arms Establishes Different DNA-Binding Specificities across theHoxLocus

1996 • 274 citations

Crystal Structure of the MATa1/MATα2 Homeodomain Heterodimer Bound to DNA

1995 • 260 citations

Crystal structure of the yeast MATα2/MCM1/DNA ternary complex

1998 • 231 citations

The specificity of homeotic gene function

1995 • 167 citations

Comparison of X-ray and NMR structures for the Antennapedia homeodomain–DNA complex

1998 • 138 citations

Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage.

1996 • 136 citations

Homeodomain interactions

1996 • 125 citations

Extradenticle protein is a selective cofactor for the Drosophila homeotics: role of the homeodomain and YPWM amino acid motif in the interaction.

1995 • 122 citations

An extradenticle-induced conformational change in a HOX protein overcomes an inhibitory function of the conserved hexapeptide motif.

1996 • 117 citations

Structure of the even-skipped homeodomain complexed to AT-rich DNA: new perspectives on homeodomain specificity.

1995 • 115 citations

Structural Determinants within Pbx1 That Mediate Cooperative DNA Binding with Pentapeptide-Containing Hox Proteins: Proposal for a Model of a Pbx1-Hox-DNA Complex

1996 • 110 citations

extradenticle determines segmental identities throughout Drosophila development

1995 • 109 citations

A structural model for a homeotic protein-extradenticle-DNA complex accounts for the choice of HOX protein in the heterodimer.

1996 • 108 citations

Distinct HOX N-terminal Arm Residues Are Responsible for Specificity of DNA Recognition by HOX Monomers and HOX·PBX Heterodimers

1997 • 65 citations