Human mucin gene MUC4: organization of its 5′-region and polymorphism of its central tandem repeat array

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1987 • 5,139 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin.

1990 • 994 citations

Epithelial Mucin Genes

1995 • 982 citations

Transfer of Proteins Across Membranes

1981 • 894 citations

Molecular cloning, sequence, and specificity of expression of the gene encoding the low molecular weight human salivary mucin (MUC7).

1993 • 461 citations

Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization.

1993 • 455 citations

Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor.

1994 • 428 citations

Molecular cloning and chromosomal localization of a novel human tracheo-bronchial mucin cDNA containing tandemly repeated sequences of 48 base pairs

1991 • 405 citations

Mucin Biophysics

1995 • 327 citations

Intron‐dependent evolution: Preferred types of exons and introns

1987 • 300 citations

The human MUC2 intestinal mucin has cysteine-rich subdomains located both upstream and downstream of its central repetitive region.

1992 • 270 citations

Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism

1991 • 225 citations

Human Mucin Genes Assigned to 11p15.5: Identification and Organization of a Cluster of Genes

1996 • 225 citations

Cosmid vectors for rapid genomic walking, restriction mapping, and gene transfer.

1987 • 222 citations

Characterization of the human mucin gene MUC5AC: a consensus cysteine-rich domain for 11p15 mucin genes?

1995 • 208 citations

MUC-2 human small intestinal mucin gene structure. Repeated arrays and polymorphism.

1991 • 187 citations

Functions of signal and signal-anchor sequences are determined by the balance between the hydrophobic segment and the N-terminal charge.

1992 • 180 citations

Translocation of proteins across membranes: the signal hypothesis and beyond.

1979 • 176 citations

The specificity of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase as inferred from a database of in vivo substrates and from the in vitro glycosylation of proteins and peptides

1993 • 173 citations

Altered expression of MUC2, MUC4, and MUC5 mucin genes in pancreas tissues and cancer cell lines

1994 • 171 citations

Signal Transduction Packaging and Secretion of Mucins

1995 • 169 citations

Human Mucin Gene MUC5B, the 10.7-kb Large Central Exon Encodes Various Alternate Subdomains Resulting in a Super-repeat

1997 • 166 citations

Chromosomal localization of a human mucin gene (MUC8) and cloning of the cDNA corresponding to the carboxy terminus.

1997 • 151 citations

Expression of MUC1, MUC2, MUC3 and MUC4 mucin mrnas in human pancreatic and intestinal tumor cell lines

1994 • 145 citations

Mucin gene expression in colonic tissues and cell lines.

1992 • 144 citations

Genomic Organization of the 3′ Region of the Human Mucin GeneMUC5B

1997 • 118 citations

The Carboxyl-terminal Sequence of the Human Secretory Mucin, MUC6

1997 • 110 citations

MUC1 gene polymorphism and gastric cancer--an epidemiological study.

1997 • 99 citations

A tripartite structure of the signals that determine protein insertion into the endoplasmic reticulum membrane.

1989 • 98 citations

Characterization of a Mucin cDNA Clone Isolated from HT-29 Mucus-secreting Cells.

1995 • 96 citations

Mucin gene expression in the human endocervix

1995 • 89 citations

Evolutionary History of the 11p15 Human Mucin Gene Family

1998 • 81 citations

Molecular cloning of the amino-terminal region of a rat MUC 2 mucin gene homologue. Evidence for expression in both intestine and airway.

1994 • 79 citations

Molecular cloning and sequencing of the mucin subunit of a heterodimeric, bifunctional cell surface glycoprotein complex of ascites rat mammary adenocarcinoma cells.

1994 • 73 citations

Membrane-Bound (MUC1) and Secretory (MUC2, MUC3, and MUC4) Mucin Gene Expression in Human Lung Cancer

1996 • 70 citations

The functional efficiency of a mammalian signal peptide is directly related to its hydrophobicity.

1990 • 57 citations

The Complete cDNA Sequence and Structural Polymorphism of the Polypeptide Chain of Porcine Submaxillary Mucin

1997 • 57 citations

Expression of MUC2 epithelial mucin in breast carcinoma.

1993 • 54 citations

Novel multigene families encoding highly repetitive peptide sequences. Sequence analyses of rat and mouse proline-rich protein cDNAs.

1985 • 51 citations

Protein processing within the secretory pathway

1992 • 49 citations

Diversity of the peptide moiety of human airway mucins

1990 • 49 citations

Mucin 4 (MUC4) gene: regional assignment (3q29) and RFLP analysis.

1992 • 38 citations

Human submandibular gland statherin and basic histidine-rich peptide are encoded by highly abundant mRNA's derived from a common ancestral sequence

1987 • 35 citations

Signification fonctionnelle des séquences signal : leur rôle dans le transfert des lactoprotéines à travers les membranes du réticulum endoplasmique

1981 • 2 citations