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2000 • 1,941 citations

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

1999 • 1,589 citations

Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression

1996 • 1,201 citations

A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: The PPARα-null mouse as a model of fatty acid oxidation disorders

1999 • 931 citations

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1997 • 594 citations

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1994 • 554 citations

Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex

1998 • 552 citations

PPAR Signaling in the Control of Cardiac Energy Metabolism

2000 • 483 citations

Deactivation of peroxisome proliferator–activated receptor-α during cardiac hypertrophic growth

2000 • 452 citations

Peroxisome proliterator-activated receptor-alpha activators regulate genes governing lipoprotein metabolism, vascular inflammation and atherosclerosis

1999 • 421 citations

Energy metabolism of the heart: From basic concepts to clinical applications applications

1994 • 399 citations

Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart

1998 • 311 citations

Constitutive Regulation of Cardiac Fatty Acid Metabolism through Peroxisome Proliferator-activated Receptor α Associated with Age-dependent Cardiac Toxicity

2000 • 308 citations

Mechanism responsible for inactivation of skeletal muscle pyruvate dehydrogenase complex in starvation and diabetes.

1999 • 288 citations

Regulation of Lipid and Lipoprotein Metabolism by PPAR Activators

2000 • 275 citations

THE NUCLEAR HORMONE RECEPTOR GENE SUPERFAMILY

1995 • 260 citations

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1999 • 231 citations

Uncoupling protein 3 transcription is regulated by peroxisome proliferator‐activated receptor α in the adult rodent heart

2001 • 225 citations

Peroxisome Proliferator-activated Receptor α Controls the Hepatic CYP4A Induction Adaptive Response to Starvation and Diabetes

1998 • 211 citations

Adaptive Increase in Pyruvate Dehydrogenase Kinase 4 during Starvation Is Mediated by Peroxisome Proliferator-Activated Receptor α

2001 • 203 citations

Role of peroxisome proliferator-activated receptor α in disease of pancreatic β cells

1998 • 178 citations

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2000 • 168 citations

Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth.

1999 • 158 citations

Inhibition of peroxisome-proliferator-activated receptor (PPAR)α by MK886

2001 • 151 citations

Disturbances in the normal regulation of SREBP-sensitive genes in PPARα-deficient mice

2001 • 140 citations

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2001 • 101 citations

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1998 • 91 citations

Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply

2000 • 83 citations

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1990 • 62 citations

Time courses of the responses of pyruvate dehydrogenase activities to short-term starvation in diaphragm and selected skeletal muscles of the rat

1989 • 55 citations

Fasting-induced changes in the expression of genes controlling substrate metabolism in the rat heart

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Long‐term regulation of pyruvate dehydrogenase kinase by high‐fat feeding

1993 • 49 citations

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1997 • 44 citations

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1995 • 35 citations

Fuel-sensing mechanisms integrating lipid and carbohydrate utilization

2001 • 34 citations

The Long-Term Regulation of Skeletal Muscle Pyruvate Dehydrogenase Kinase by Dietary Lipid is Dependent on Fatty Acid Composition

1995 • 29 citations

Peroxisome proliferator-activated receptor-α ligands inhibit cardiac lipoprotein lipase activity

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Longer-term regulation of pyruvate dehydrogenase kinase in cultured rat cardiac myocytes

1990 • 28 citations

Mechanisms regulating cardiac fuel selection in hyperthyroidism

1992 • 27 citations

Interactive effects of insulin and triiodothyronine on pyruvate dehydrogenase kinase activity in cardiac myocytes

1995 • 27 citations

Heterodimerization and deoxyribonucleic acid-binding properties of a retinoid X receptor-related factor.

1994 • 25 citations

Molecular Mechanisms Underlying the Long-term Impact of Dietary Fat to Increase Cardiac Pyruvate Dehydrogenase Kinase: Regulation by Insulin, Cyclic AMP and Pyruvate

1997 • 24 citations

Expression and regulation of pyruvate dehydrogenase kinase isoforms in the developing rat heart and in adulthood: role of thyroid hormone status and lipid supply

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1996 • 21 citations

Glucose utilization by skeletal muscles in vivo in experimental hyperthyroidism in the rat

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Lipoprotein Lipase Activity and Chylomicron Clearance in Rats Fed a High Fat Diet

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Heterodimerization and deoxyribonucleic acid-binding properties of a retinoid X receptor-related factor

1994 • 8 citations

Site-selective modulation of enzymes of cardiac fuel utilization by a diet rich in fat

1994 • 1 citations