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Attenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly attenuated strain when combined in vitro

Data up to Jan 2025

Published1990
Citations44
References32

Total Citations Per Year

Abstract

References (32)

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12

1938 • 19,183 citations

A simple method of estimating 50 per cent end points

1938 • 8,381 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

Cloned Poliovirus Complementary DNA Is Infectious in Mammalian Cells

1981 • 686 citations

Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants

1987 • 476 citations

Complete nucleotide sequence of the genomic RNA of Sindbis virus

1984 • 393 citations

The Togaviridae and Flaviviridae

1986 • 367 citations

The T=4 envelope of sindbis virus is organized by interactions with a complementary T=3 capsid

1987 • 337 citations

Molecular basis of Sindbis virus neurovirulence in mice

1988 • 257 citations

Genetic basis of attenuation of the Sabin type 3 oral poliovirus vaccine

1989 • 237 citations

3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors.

1978 • 214 citations

Genetic analysis of the attenuation phenotype of poliovirus type 1

1986 • 191 citations

Age-dependent Resistance to Viral Encephalitis: Studies of Infections Due to Sindbis Virus in Mice

1972 • 147 citations

Sindbis virus glycoproteins form a regular icosahedral surface lattice

1975 • 122 citations

A single nucleotide change in the E2 glycoprotein gene of Sindbis virus affects penetration rate in cell culture and virulence in neonatal mice.

1986 • 98 citations

VIRUS INVASION OF THE CENTRAL NERVOUS SYSTEM: A STUDY OF SINDBIS VIRUS INFECTION IN THE MOUSE USING FLUORESCENT ANTIBODY.

1965 • 84 citations

Sindbis virus mutations which coordinately affect glycoprotein processing, penetration, and virulence in mice

1989 • 82 citations

Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro

1988 • 77 citations

Mapping of attenuating sequences of an avirulent poliovirus type 2 strain

1989 • 70 citations

Studies on the nature of dengue viruses

1967 • 68 citations

Sindbis Virus Mutants Selected for Rapid Growth in Cell Culture Display Attenuated Virulence in Animals

1984 • 67 citations

Characterization of Sindbis virus epitopes important for penetration in cell culture and pathogenesis in animals

1986 • 61 citations

Age-Dependent Resistance of Mice to Sindbis Virus Infection: Viral Replication as a Function of Host Age

1971 • 56 citations

Low pH-dependent sindbis virus-induced fusion of bhk cells: Differences between strains correlate with amino acid changes in the E1 glycoprotein

1989 • 48 citations

Viruses of vertebrates, 3rd edition

1973 • 28 citations

A sindbis virus variant with a cell-determined latent period

1981 • 26 citations

The Virus Envelope in Cell Attachment

1970 • 23 citations

IN VITRO SELECTION OF AN ATTENUATED VARIANT OF SINDBIS VIRUS

1980 • 11 citations

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Attenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly… (1990) – Journal of Virology | Metascience Observatory Explorer