Attenuating mutations in glycoproteins E1 and E2 of Sindbis virus produce a highly attenuated strain when combined in vitro
Data up to Jan 2025
Total Citations Per Year
Abstract
References (32)
Molecular Cloning: A Laboratory Manual
2001 • 133,517 citations
DNA sequencing with chain-terminating inhibitors
1977 • 69,181 citations
A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS12
1938 • 19,183 citations
A simple method of estimating 50 per cent end points
1938 • 8,381 citations
Rapid and efficient site-specific mutagenesis without phenotypic selection.
1985 • 7,573 citations
[19] Rapid and efficient site-specific mutagenesis without phenotypic selection
1987 • 5,413 citations
A rapid boiling method for the preparation of bacterial plasmids
1981 • 3,334 citations
Cloned Poliovirus Complementary DNA Is Infectious in Mammalian Cells
1981 • 686 citations
Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants
1987 • 476 citations
Complete nucleotide sequence of the genomic RNA of Sindbis virus
1984 • 393 citations
The Togaviridae and Flaviviridae
1986 • 367 citations
The T=4 envelope of sindbis virus is organized by interactions with a complementary T=3 capsid
1987 • 337 citations
Molecular basis of Sindbis virus neurovirulence in mice
1988 • 257 citations
Genetic basis of attenuation of the Sabin type 3 oral poliovirus vaccine
1989 • 237 citations
3'-terminal nucleotide sequence of encephalomyocarditis virus RNA determined by reverse transcriptase and chain-terminating inhibitors.
1978 • 214 citations
Genetic analysis of the attenuation phenotype of poliovirus type 1
1986 • 191 citations
Age-dependent Resistance to Viral Encephalitis: Studies of Infections Due to Sindbis Virus in Mice
1972 • 147 citations
Sindbis virus glycoproteins form a regular icosahedral surface lattice
1975 • 122 citations
A single nucleotide change in the E2 glycoprotein gene of Sindbis virus affects penetration rate in cell culture and virulence in neonatal mice.
1986 • 98 citations
VIRUS INVASION OF THE CENTRAL NERVOUS SYSTEM: A STUDY OF SINDBIS VIRUS INFECTION IN THE MOUSE USING FLUORESCENT ANTIBODY.
1965 • 84 citations
Sindbis virus mutations which coordinately affect glycoprotein processing, penetration, and virulence in mice
1989 • 82 citations
Molecular analysis of Sindbis virus pathogenesis in neonatal mice by using virus recombinants constructed in vitro
1988 • 77 citations
Mapping of attenuating sequences of an avirulent poliovirus type 2 strain
1989 • 70 citations
Studies on the nature of dengue viruses
1967 • 68 citations
Sindbis Virus Mutants Selected for Rapid Growth in Cell Culture Display Attenuated Virulence in Animals
1984 • 67 citations
Characterization of Sindbis virus epitopes important for penetration in cell culture and pathogenesis in animals
1986 • 61 citations
Age-Dependent Resistance of Mice to Sindbis Virus Infection: Viral Replication as a Function of Host Age
1971 • 56 citations
Low pH-dependent sindbis virus-induced fusion of bhk cells: Differences between strains correlate with amino acid changes in the E1 glycoprotein
1989 • 48 citations
Viruses of vertebrates, 3rd edition
1973 • 28 citations
A sindbis virus variant with a cell-determined latent period
1981 • 26 citations
The Virus Envelope in Cell Attachment
1970 • 23 citations
IN VITRO SELECTION OF AN ATTENUATED VARIANT OF SINDBIS VIRUS
1980 • 11 citations