Quantitative prediction of the interaction of midazolam and histamine H2 receptor antagonists in rats.

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

1996 • 2,895 citations

A pharmacokinetic analysis program (multi) for microcomputer.

1981 • 2,465 citations

Active secretion and enterocytic drug metabolism barriers to drug absorption

1996 • 310 citations

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

1995 • 295 citations

The influence of quinolone derivatives on theophylline clearance.

1986 • 258 citations

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole.

1996 • 220 citations

Recent advances in carrier-mediated hepatic uptake and biliary excretion of xenobiotics.

1996 • 218 citations

Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals.

1994 • 166 citations

Differential inhibition of individual human liver cytochromes P-450 by cimetidine

1991 • 118 citations

In vitro forecasting of drugs which may interfere with the biotransformation of midazolam

1991 • 107 citations

Cimetidine and ranitidine increase midazolam bioavailability

1987 • 84 citations

Pharmacokinetic‐pharmacodynamic modelling of the EEG effects of midazolam in individual rats: influence of rate and route of administration

1991 • 83 citations

Enoxacin ? a potent inhibitor of theophylline metabolism

1987 • 77 citations

Method to estimate the rate and extent of intestinal absorption in conscious rats using an absorption probe and portal blood sampling.

1995 • 57 citations

A clinically significant interaction between ciprofloxacin and theophylline

1987 • 47 citations

Troleandomycin-triazolam interaction in healthy volunteers: Pharmacokinetic and psychometric evaluation

1987 • 47 citations

Itraconazole interacts with felodipine

1995 • 44 citations

Ranitidine influences the uptake of oral midazolam.

1983 • 40 citations

Effect of five structurally diverse H2-receptor antagonists on drug metabolism

1986 • 36 citations

Carrier-mediated active transport of histamine H2 receptor antagonists, cimetidine and nizatidine, into isolated rat hepatocytes: contribution of type I system.

1994 • 31 citations

Absence of interaction of cimetidine and ranitidine with intravenous and oral midazolam.

1986 • 28 citations

Local absorption kinetics of levofloxacin from intestinal tract into portal vein in conscious rat using portal-venous concentration difference.

1996 • 28 citations

Alteration of Pharmacokinetic Features Caused by Drug Interactions.

1996 • 7 citations

Cimetidine: An inhibitor and an inducer of rat liver microsomal cytochrome P-450

1991 • 7 citations

Effect of renal or hepatic dysfunction on neurotoxic convulsion induced by ranitidine in mice.

1994 • 6 citations