Transplantation of Human Umbilical Cord Blood Cells in Macrophage-Depleted SCID Mice: Evidence for Accessory Cell Involvement in Expansion of Immature CD34+CD38−Cells

High gradient magnetic cell separation with MACS

1990 • 1,648 citations

The SCID-hu Mouse: Murine Model for the Analysis of Human Hematolymphoid Differentiation and Function

1988 • 1,394 citations

Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.

1995 • 1,223 citations

Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells.

1989 • 1,220 citations

Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice

1997 • 879 citations

Sequential generations of hematopoietic colonies derived from single nonlineage-committed CD34+CD38- progenitor cells

1991 • 869 citations

Primitive Human Hematopoietic Cells Are Enriched in Cord Blood Compared With Adult Bone Marrow or Mobilized Peripheral Blood as Measured by the Quantitative In Vivo SCID-Repopulating Cell Assay

1997 • 488 citations

Engraftment of Immune-Deficient Mice with Human Hematopoietic Stem Cells

1988 • 471 citations

A functional comparison of CD34 + CD38- cells in cord blood and bone marrow

1995 • 456 citations

The liposome-mediated macrophage ‘suicide’ technique

1989 • 455 citations

A novel population of expanded human CD3+CD56+ cells derived from T cells with potent in vivo antitumor activity in mice with severe combined immunodeficiency.

1994 • 438 citations

Long-term human hematopoiesis in the SCID-hu mouse.

1990 • 353 citations

Evidence of functional lymphocytes in some (leaky) scid mice.

1988 • 347 citations

Partial replacement of serum by selenite, transferrin, albumin and lecithin in haemopoitec cell cultures

1976 • 319 citations

Immature human cord blood progenitors engraft and proliferate to high levels in severe combined immunodeficient mice

1994 • 283 citations

Kinetic Evidence of the Regeneration of Multilineage Hematopoiesis From Primitive Cells in Normal Human Bone Marrow Transplanted Into Immunodeficient Mice

1997 • 247 citations

Engraftment and Development of Human CD34+-Enriched Cells From Umbilical Cord Blood in NOD/LtSz-scid/scid Mice

1997 • 215 citations

Implantation and maintenance of functional human bone marrow in SCID-hu mice

1992 • 209 citations

Phenotype and function of human hematopoietic cells engrafting immune- deficient CB17-severe combined immunodeficiency mice and nonobese diabetic-severe combined immunodeficiency mice after transplantation of human cord blood mononuclear cells

1996 • 204 citations

Novel surface antigen expressed on dividing cells but absent from nondividing cells.

1980 • 123 citations

Individual CD34+CD38lowCD19−CD10− Progenitor Cells From Human Cord Blood Generate B Lymphocytes and Granulocytes

1997 • 112 citations

Hematopoietic potential of cryopreserved and ex vivo manipulated umbilical cord blood progenitor cells evaluated in vitro and in vivo

1996 • 104 citations

Growth of human myeloid leukemias in the human marrow environment of SCID-hu mice

1993 • 89 citations

Improved engraftment of human hematopoietic cells in severe combined immunodeficient (SCID) mice carrying human cytokine transgenes.

1995 • 87 citations

Circulation of human hematopoietic cells in severe combined immunodeficient mice after Cl2MDP-liposome-mediated macrophage depletion

1995 • 61 citations

Human allogeneic stem cell maintenance and differentiation in a long- term multilineage SCID-hu graft

1995 • 56 citations

Possible mechanisms accounting for the growth factor independence of hematopoietic progenitors from umbilical cord blood

1994 • 53 citations

Transplantation of umbilical cord blood in Fanconi's anemia.

1990 • 52 citations

Preclinical analysis of cytokine therapy in the SCID-hu mouse

1993 • 50 citations

ERYTHROPOIETIN‐INDEPENDENT REGENERATION OF ERYTHROID PROGENITOR CELLS FOLLOWING MULTIPLE INJECTIONS OF HYDROXYUREA

1980 • 44 citations

Detection of murine bone marrow granulocyte/macrophage progenitor cells (GM‐CFU) in serum‐free cultures stimulated with purified M‐CSF or GM‐CSF

1984 • 40 citations

Long-term human hematopoiesis in SCID-hu mice bearing transplanted fragments of adult bone and bone marrow cells

1995 • 36 citations

Conditions for engraftment of human acute myeloid leukemia (AML) in SCID mice.

1995 • 36 citations

SCID mice as an in vivo model of human cord blood hematopoiesis.

1994 • 35 citations

Facilitated engraftment of human hematopoietic cells in severe combined immunodeficient mice following a single injection of Cl2MDP liposomes

1997 • 34 citations

Umbilical cord blood cell transduction by retroviral vectors: preclinical studies to optimize gene transfer.

1994 • 29 citations

Konservierung von h�mopoetischen Stammzellen

1975 • 9 citations

[Cryopreservation of hemopoietic stem cells].

1982 • 8 citations