Effects of cysteine protease inhibitors on rabbit cathepsin D maturation

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

The trans Golgi Network: Sorting at the Exit Site of the Golgi Complex

1986 • 1,175 citations

LYSOSOMAL ENZYMES AND THEIR RECEPTORS

1986 • 915 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

PROTEIN DEGRADATION IN CULTURED CELLS

1974 • 603 citations

In vitro degradation of extracellular matrix with Mr 52,000 cathepsin D secreted by breast cancer cells.

1988 • 242 citations

Lysosomal Enzyme Precursors in Human Fibroblasts. Activation of Cathepsin D Precursor in vitro and Activity of beta-Hexosaminidase A Precursor towards Ganglioside GM2

1982 • 163 citations

Enhanced degradation of cathepsin D synthesized in the presence of the threonine analog β-hydroxynorvaline

1984 • 46 citations

Inhibition of early but not late proteolytic processing events leads to the missorting and oversecretion of precursor forms of lysosomal enzymes in Dictyostelium discoideum.

1988 • 44 citations

Subcellular redistribution of newly synthesized macrophage lysosomal enzymes. Correlation between delivery to the lysosomes and maturation.

1983 • 44 citations

Identification of a precursor form of cathepsin D in microsomal lumen: Characterization of enzymatic activation and proteolytic processing

1987 • 35 citations

The effect of chloroquine on the distribution of newly synthesized and old β-hexosaminidase in fibroblasts

1982 • 12 citations

Regulation of Cathepsin D Metabolism in Rabbit Heart

1982 • 9 citations

Identification of artifactual cathepsin D activity in cardiac subcellular fractions related to formation of an iron-EDTA complex

1985 • 3 citations