The effect of chloroquine on the distribution of newly synthesized and old β-hexosaminidase in fibroblasts

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Lactic Dehydrogenase Activity in Blood.

1955 • 2,433 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

1980 • 809 citations

Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.

1980 • 743 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Phosphorylation of mannose residues.

1980 • 404 citations

Recognition and receptor-mediated uptake of a lysosomal enzyme, α-l-iduronidase, by cultured human fibroblasts

1977 • 354 citations

Fibroblasts from patients with I-cell disease and pseudo-Hurler polydystrophy are deficient in uridine 5'-diphosphate-N-acetylglucosamine: glycoprotein N-acetylglucosaminylphosphotransferase activity.

1981 • 323 citations

Phosphomannosyl-enzyme receptors in rat liver. Subcellular distribution and role in intracellular transport of lysosomal enzymes.

1980 • 231 citations

Biosynthetic intermediates of beta-glucuronidase contain high mannose oligosaccharides with blocked phosphate residues.

1980 • 225 citations

Evidence for lysosomal enzyme recognition by human fibroblasts via a phosphorylated carbohydrate moiety

1978 • 185 citations

Phosphohexosyl recognition is a general characteristic of pinocytosis of lysosomal glycosidases by human fibroblasts.

1977 • 181 citations

Phosphorylated oligosaccharides in lysosomal enzymes: identification of alpha-N-acetylglucosamine(1)phospho(6)mannose diester groups.

1980 • 131 citations

Australia Antigen in Volunteer and Paid Blood Donors

1971 • 123 citations

Effect of chloroquine on cultured fibroblasts: Release of lysosomal hydrolases and inhibition of their uptake

1975 • 115 citations

An alternative hypothesis of cellular transport of lysosomal enzymes in fibroblasts. Effect of inhibitors of lysosomal enzyme endocytosis on intra- and extra-cellular lysosomal enzyme activities

1978 • 111 citations

Abnormal lysosomal hydrolases excreted by cultured fibroblasts in I-cell disease (mucolipidosis II)

1975 • 92 citations

Inhibition of receptor-mediated uptake of a lysosomal enzyme into fibroblasts by chloroquine, procaine and ammonia

1979 • 85 citations

Multiple isoelectric and recognition forms of human β-glucuronidase activity

1975 • 84 citations

I-cell disease: Deficiency of extracellular hydrolase phosphorylation

1979 • 82 citations

Excretion-Reuptake Route of β-Hexosaminidase in Normal and I-Cell Disease Cultured Fibroblasts

1979 • 76 citations

Secretion and uptake of ß-N-acetylglucosaminidase by fibroblasts Effect of chloroquine and mannose 6-phosphate

1979 • 35 citations

Intracellular Localization of Exogenous β‐Glucuronidase in Cultured Skin Fibroblasts

1979 • 18 citations

LOCALIZATION OF A PRIMATE-SPECIFIC ESTERASE USING IMMUNOFLUORESCENCE AND IMMUNOPEROXIDASE TECHNIQUES

1973 • 16 citations

Chloroquine inhibits the insulin production of isolated pancreatic islets

1980 • 14 citations

Compartmental distribution of β-hexosaminidase isoenzymes in I-cell fibroblasts

1981 • 7 citations