Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes.

PROTEIN-TYROSINE KINASES

1985 • 2,198 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

A thousand and one protein kinases

1987 • 1,066 citations

Autophosphorylation sites on the epidermal growth factor receptor

1984 • 730 citations

The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes.

1988 • 716 citations

Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lck

1989 • 671 citations

A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA

1985 • 550 citations

Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines.

1983 • 377 citations

T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4.

1984 • 302 citations

The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation

1989 • 301 citations

Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertion

1986 • 290 citations

Monoclonal antibodies to phosphotyrosine

1988 • 242 citations

Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck).

1988 • 232 citations

Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts.

1988 • 208 citations

Alterations of the Lymphocyte-Specific Protein Tyrosine Kinase (p56^lck) during T-Cell Activation

1988 • 169 citations

Expression of the lck tyrosine kinase gene in human colon carcinoma and other non-lymphoid human tumor cell lines.

1987 • 132 citations

Characterization of the protein apparently responsible for the elevated tyrosine protein kinase activity in LSTRA cells.

1984 • 121 citations

Covalently bound myristate in a lymphoma tyrosine protein kinase.

1984 • 120 citations

Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C.

1988 • 103 citations

Comodulation of CD3 and CD4. Evidence for a specific association between CD4 and approximately 5% of the CD3:T cell receptor complexes on helper T lymphocytes.

1988 • 89 citations

Adoptive chemoimmunotherapy of murine leukemia with helper T lymphocyte clones.

1987 • 39 citations

Characterization of the Protein Apparently Responsible for the Elevated Tyrosine Protein Kinase Activity in LSTRA Cells

1984 • 36 citations

The Biologic Roles Of CD2, CD4, And CD8 In T-Cell Activation

1989 • 16 citations