Intracellular diadenosine polyphosphates

ATP-regulated K+ channels in cardiac muscle

1983 • 2,350 citations

Physiological roles and properties of potassium channels in arterial smooth muscle

1995 • 2,146 citations

Reconstitution of I _KATP : An Inward Rectifier Subunit Plus the Sulfonylurea Receptor

1995 • 1,703 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

1984 • 1,199 citations

Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells

1984 • 1,099 citations

A Family of Sulfonylurea Receptors Determines the Pharmacological Properties of ATP-Sensitive K+ Channels

1996 • 968 citations

Properties and functions of ATP-sensitive K-channels

1990 • 690 citations

A Novel Sulfonylurea Receptor Forms with BIR (Kir6.2) a Smooth Muscle Type ATP-sensitive K+ Channel

1996 • 539 citations

Adenosine Diphosphate as an Intracellular Regulator of Insulin Secretion

1996 • 532 citations

P1,P5-Di(adenosine-5′)pentaphosphate, a Potent Multisubstrate Inhibitor of Adenylate Kinase

1973 • 524 citations

Adenosine triphosphate-sensitive potassium channels in the cardiovascular system

1991 • 440 citations

AppppA, heat-shock stress, and cell oxidation.

1983 • 379 citations

Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs

1995 • 309 citations

Mechanism of potassium efflux and action potential shortening during ischaemia in isolated mammalian cardiac muscle.

1990 • 145 citations

Subcellular Distribution Studies of Diadenosine Polyphosphates—Ap₄A and Ap₅A—in Bovine Adrenal Medulla: Presence in Chromaffin Granules

1988 • 138 citations

Diadenosine 5′, 5′′′-P1, P4-tetraphosphate: a pleiotropically acting alarmone?

1983 • 137 citations

Electrophysiological effects of ATP sensitive potassium channel modulation: implications for arrhythmogenesis

1994 • 131 citations

K+ channel openers and ‘natural’ cardioprotection

1992 • 112 citations

Adenylate Kinase-catalyzed Phosphoryl Transfer Couples ATP Utilization with Its Generation by Glycolysis in Intact Muscle

1995 • 108 citations

Actin microfilament disrupters enhance K(ATP) channel opening in patches from guinea‐pig cardiomyocytes.

1996 • 104 citations

Identification of an ATP-sensitive K+ channel in rat cultured cortical neurons

1992 • 104 citations

ATP-sensitive potassium channels and myocardial preconditioning

1995 • 98 citations

Alteration of adenyl dinucleotide metabolism by environmental stress.

1986 • 98 citations

Suppression of Creatine Kinase-catalyzed Phosphotransfer Results in Increased Phosphoryl Transfer by Adenylate Kinase in Intact Skeletal Muscle

1996 • 95 citations

G proteins activate ATP-sensitive K+ channels by antagonizing ATP-dependent gating

1994 • 88 citations

AppppA binds to several proteins in Escherichia coli, including the heat shock and oxidative stress proteins DnaK, GroEL, E89, C45 and C40.

1991 • 87 citations

Diadenosine polyphosphates: Their biological and pharmacological significance

1995 • 82 citations

Metabolic regulation of cardiac ATP-sensitive K+ channels

1993 • 80 citations

Dualistic behavior of ATP-sensitive K+ channels toward intracellular nucleoside diphosphates

1994 • 69 citations

Protective effects of ATP sensitive potassium channel openers in models of myocardial ischaemia

1994 • 61 citations

Nucleotide regulation of ATP sensitive potassium channels

1994 • 60 citations

Reversal of the ATP-liganded State of ATP-sensitive K+ Channels by Adenylate Kinase Activity

1996 • 60 citations

A disrupter of actin microfilaments impairs sulfonylurea-inhibitory gating of cardiac KATP channels

1996 • 58 citations

ATP-Sensitive Potassium Channels

1994 • 58 citations

Diadenosine Polyphosphates: A Novel Class of Glucose-Induced Intracellular Messengers in the Pancreatic β-Cell

1996 • 57 citations

Suppression of Adenylate Kinase Catalyzed Phosphotransfer Precedes and Is Associated with Glucose-induced Insulin Secretion in Intact HIT-T15 Cells

1996 • 49 citations

Inhibition of carbamyl phosphate synthetase by P1, P5-di(adenosine 5')-pentaphosphate: evidence for two ATP binding sites.

1977 • 49 citations

Inhibition of adenosine and thymidylate kinases by bisubstrate analogs.

1986 • 48 citations

Interactive regulation of the ATP-sensitive potassium channel of cardiac muscle.

1994 • 40 citations

The role of potassium channels in excitable cells

1995 • 37 citations

Dual effect of glyburide, an antagonist of KATP channels, on metabolic inhibition-induced Ca2+ loading in cardiomyocytes

1996 • 35 citations

HOE-234, a second generation K+ channel opener, antagonizes the ATP-dependent gating of cardiac ATP-sensitive K+ channels.

1994 • 29 citations

Diadenosine polyphosphate-induced inhibition of cardiac KATP channels: Operative state-dependent regulation by a nucleoside diphosphate

1996 • 27 citations

The ATP sensitive potassium channel of cardiac muscle and action potential shortening during metabolic stress

1994 • 27 citations

Cardiac ATP-sensitive K+ channel: a target for diadenosine 5?,5?-P1,P5-pentaphosphate

1996 • 18 citations

Cytosolic Ca2+ domain-dependent protective action of adenosine in cardiomyocytes

1996 • 16 citations

Diadenosine tetraphosphate‐induced inhibition of ATP‐sensitive K⁺ channels in patches excised from ventricular myocytes

1996 • 16 citations

Diadenosine-hexaphosphate is an inhibitory ligand of myocardial ATP-sensitive K+ channels

1995 • 15 citations

Interactive Regulation of the ATP-Sensitive Potassium Channel of Cardiac Muscle

1994 • 14 citations

Relaxation of human uterine artery in response to pinacidil: predominant role for ATP-dependent potassium channels.

1994 • 11 citations

In vitro competition between adenosine(5')tetraphospho(5')adenosine and deoxyribonucleic acid in the reaction with diamminedichloroplatinum(II)

1986 • 10 citations