Reduced Nerve Growth Factor in Rett Syndrome Postmortem Brain Tissue

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

1999 • 4,776 citations

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1998 • 3,363 citations

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

1998 • 2,686 citations

Proliferation and differentiation of neuronal stem cells regulated by nerve growth factor

1990 • 720 citations

Limbic Seizures Increase Neuronal Production of Messenger RNA for Nerve Growth Factor

1989 • 624 citations

The retrograde axonal transport of nerve growth factor

1974 • 598 citations

Chronic intraventricular injections of nerve growth factor elevate hippocampal choline acetyltransferase activity in adult rats with partial septo-hippocampal lesions

1984 • 446 citations

Diagnostic criteria for rett syndrome

1988 • 394 citations

p140trk mRNA marks NGF-responsive forebrain neurons: Evidence that trk gene expression is induced by NGF

1992 • 371 citations

Spectrum of human immunodeficiency virus–associated neocortical damage

1992 • 369 citations

Selective Dendritic Alterations in the Cortex of Rett Syndrome

1995 • 354 citations

Inflammatory Signals Induce Neurotrophin Expression in Human Microglial Cells

1998 • 285 citations

Rett's Syndrome: Prevalence and Impact on Progressive Severe Mental Retardation in Girls

1985 • 281 citations

Specificity of the retrograde axonal transport of nerve growth factor

1974 • 221 citations

Nerve growth factor in the nucleus: interaction with receptors on the nuclear membrane.

1979 • 191 citations

Neuroanatomy in Rett syndrome

1997 • 138 citations

Nerve growth factor is an autocrine factor essential for the survival of macrophages infected with HIV

1999 • 127 citations

A New Rett Syndrome Family Consistent with X-Linked Inheritance Expands the X Chromosome Exclusion Map

1997 • 115 citations

Cerebrospinal fluid biogenic amines and biopterin in rett syndrome

1989 • 104 citations

Studies on the 3-dimensional architecture of dendritic spines and varicosities in human cortex by confocal laser scanning microscopy and Lucifer Yellow microinjections

1995 • 87 citations

The Neuropathology of Rett Syndrome - Overview 1994

1995 • 81 citations

Altered Cholinergic Function in the Basal Forebrain of Girls with Rett Syndrome

1999 • 77 citations

Multiple Levels for Regulation of TrkA in PC12 Cells by Nerve Growth Factor

1995 • 71 citations

Cellular localization of nerve growth factor-like immunoreactivity in adult rat brain: Quantitative and immunohistochemical study

1994 • 65 citations

Expression of nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 in the somatosensory cortex of the mature rat: Coexpression with high-affinity neurotrophin receptors

2000 • 64 citations

Increased levels of nerve growth factor (NGF) protein and mRNA and reactive gliosis following kainic acid injection into the rat striatum

1994 • 62 citations

Intracellular distribution of nerve growth factor in rat pheochromocytoma PC12 cells: evidence for a perinuclear and intranuclear location.

1980 • 60 citations

Low Levels of Nerve Growth Factor in Cerebrospinal Fluid of Children With Rett Syndrome

1996 • 56 citations

Chromosome mapping of Rett syndrome: a likely candidate region on the telomere of Xq.

1998 • 45 citations

Neurotrophic Factors in Cerebrospinal Fluid and Serum of Patients With Rett Syndrome

1998 • 35 citations

X chromosome-inactivation patterns in patients with Rett syndrome

1998 • 33 citations

Expression of Nerve Growth Factor, p75, andtrkin the Somatosensory and Motor Cortices of Mature Rats: Evidence for Local Trophic Support Circuits

1995 • 33 citations

Rett Syndrome Studies of Natural History and Search for a Genetic Marker

1995 • 31 citations

Male Rett Variant

1995 • 28 citations

Nerve growth factor induces trkA mRNA expression in cultured basal forebrain cholinergic neurons from 17-day fetal rats

1994 • 24 citations

Astrocyte activation by Sindbis virus: Expression of GFAP, cytokines, and adhesion molecules

1997 • 24 citations

Astrocyte activation by Sindbis virus: Expression of GFAP, cytokines, and adhesion molecules

1997 • 23 citations

Molecular and Neurobiology Aspects of Rett Syndrome

1995 • 21 citations

Meeting Report: Second International Rett Syndrome Workshop and Symposium (8-11 October 1992, Orlando, Florida, USA)

1993 • 13 citations

Rett syndrome

1995 • 13 citations

Classical Rett syndrome in sisters: variability of clinical expression

1997 • 9 citations