High-density lipoprotein (HDL3)-associated α-tocopherol is taken up by HepG2 cells via the selective uptake pathway and resecreted with endogenously synthesized apo-lipoprotein B-rich lipoprotein particles

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor

1996 • 2,293 citations

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

1983 • 1,639 citations

Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line

1979 • 1,305 citations

High density lipoprotein metabolism.

1984 • 1,230 citations

Antioxidants in relation to lipid peroxidation

1987 • 684 citations

Role of oxidatively modified LDL in atherosclerosis

1990 • 614 citations

Implications of the SNARE hypothesis for intracellular membrane topology and dynamics

1994 • 582 citations

Inhibition of cell proliferation by alpha-tocopherol. Role of protein kinase C.

1991 • 510 citations

Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia

1993 • 497 citations

[6] Sequential flotation ultracentrifugation

1986 • 497 citations

Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation.

1991 • 477 citations

High density lipoprotein is the major carrier of lipid hydroperoxides in human blood plasma from fasting donors.

1992 • 471 citations

Severe atherosclerosis in transgenic mice expressing simian cholesteryl ester transfer protein

1993 • 449 citations

Uptake of high-density lipoprotein-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro.

1985 • 380 citations

A nonendocytotic mechanism for the selective uptake of high density lipoprotein-associated cholesterol esters.

1987 • 319 citations

[50] Rapid isolation of lipoproteins and assessment of their peroxidation by high-performance liquid chromatography postcolumn chemiluminescence

1994 • 313 citations

Assembly and secretion of hepatic very-low-density lipoprotein

1990 • 292 citations

RRR- and SRR-alpha-tocopherols are secreted without discrimination in human chylomicrons, but RRR-alpha-tocopherol is preferentially secreted in very low density lipoproteins.

1990 • 227 citations

Discrimination between forms of vitamin E by humans with and without genetic abnormalities of lipoprotein metabolism.

1992 • 202 citations

Human plasma phospholipid transfer protein accelerates exchange/transfer of α-tocopherol between lipoproteins and cells

1995 • 182 citations

Bafilomycin inhibits proton flow through the H+ channel of vacuolar proton pumps

1994 • 160 citations

Synthetic high density lipoprotein particles. Application to studies of the apoprotein specificity for selective uptake of cholesterol esters.

1987 • 152 citations

Disruption of the Murine Lecithin:Cholesterol Acyltransferase Gene Causes Impairment of Adrenal Lipid Delivery and Up-regulation of Scavenger Receptor Class B Type I

1997 • 134 citations

Determinants of plasma vitamin E concentrations

1994 • 129 citations

The assembly and secretion of apoB 100 containing lipoproteins in Hep G2 cells. Evidence for different sites for protein synthesis and lipoprotein assembly.

1990 • 123 citations

Surface-to-core and interparticle equilibrium distributions of triglyceride-rich lipoprotein lipids.

1983 • 116 citations

Intracellular Events in the “Selective” Transport of Lipoprotein-derived Cholesteryl Esters

1996 • 115 citations

Evaluation of pathways for the cellular uptake of high density lipoprotein cholesterol esters in rabbits.

1991 • 109 citations

The measurement of nanograms of tocopherol from needle aspiration biopsies of adipose tissue: normal and abetalipoproteinemic subjects.

1983 • 106 citations

Studies on the transfer of tocopherol between lipoproteins

1992 • 106 citations

Transport and distribution of α-tocopherol in lymph, serum and liver cells in rats

1986 • 98 citations

Regulation of the selective uptake of high density lipoprotein-associated cholesteryl esters by human fibroblasts and Hep G2 hepatoma cells.

1988 • 91 citations

Radioiodination of proteins and lipoproteins using N-bromosuccinimide as oxidizing agent

1988 • 82 citations

Greater selective uptake by Hep G2 cells of high-density lipoprotein cholesteryl ester hydroperoxides than of unoxidized cholesteryl esters

1993 • 78 citations

Muscle-specific overexpression of lipoprotein lipase in transgenic mice results in increased α-tocopherol levels in skeletal muscle

1996 • 76 citations

Monensin and Brefeldin A Inhibit High Density Lipoprotein- mediated Cholesterol Efflux from Cholesterol-enriched Cells

1995 • 74 citations

Determination of α-tocopherolquinone (vitamine E quinone) in human serum, platelets, and red cell membrane samples

1987 • 62 citations

Pulse‐chase studies of the synthesis of apolipoprotein B in a human hepatoma cell line, Hep G2

1985 • 54 citations

Vitamin E : its usefulness in health and in curing diseases

1993 • 48 citations

Lipoprotein lipase mediated uptake of non-degradable ether analogues of phosphatidylcholine and cholesteryl ester by cultured cells

1984 • 46 citations

Neutral lipid transfer protein does not regulate α‐tocopherol transfer between human plasma lipoproteins

1988 • 44 citations

PROGRESSIVE NEUROMUSCULAR DISEASE IN CHILDREN WITH CHRONIC CHOLESTASIS AND VITAMIN E DEFICIENCY: CLINICAL AND MUSCLE BIOPSY FINDINGS AND TREATMENT WITH α‐TOCOPHEROL*

1982 • 42 citations

Plasma clearance and net uptake of α-tocopherol and low-density lipoprotein by tissues in WHHL and control rabbits

1992 • 35 citations

Preparation of fatty acid methyl esters from lipoprotein and macrophage lipid subclasses on thin‐layer plates

1996 • 34 citations

Implications of endogenous and exogenous lipoprotein lipase for the selective uptake of HDL3-associated cholesteryl esters by mouse peritoneal macrophages

1997 • 31 citations

Effect of Chronic Ethanol Consumption on the Content of α‐Tocopherol in Subcellular Fractions of Rat Liver

1989 • 31 citations

Role of an N-ethylmaleimide-sensitive factor in the selective cellular uptake of low-density lipoprotein free cholesterol

1995 • 29 citations

Is methyl-branching in α-tocopherol's “tail” important for its in vivo activity? Rat curative myopathy bioassay measurements of the vitamin E activity of three 2RS-n-alkyl-2,5,7,8-tetramethyl-6-hydroxychromans

1990 • 28 citations