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The Calcium Carriers of Mitochondria

Data up to Jan 2025

Published1985
Citations12
References176

Total Citations Per Year

Abstract

References (176)

CHEMIOSMOTIC COUPLING IN OXIDATIVE AND PHOTOSYNTHETIC PHOSPHORYLATION

1966 • 3,631 citations

Advances in Cyclic Nucleotide Research.

1980 • 1,465 citations

Current Topics in Bioenergetics

1991 • 1,190 citations

Transport and metabolism of calcium ions in nerve

1972 • 754 citations

The Influence of Respiration and ATP Hydrolysis on the Proton‐Electrochemical Gradient across the Inner Membrane of Rat‐Liver Mitochondria as Determined by Ion Distribution

1974 • 707 citations

Advances in Cyclic Nucleotide Research

1978 • 622 citations

Specific inhibition of mitochondrial Ca++ transport by ruthenium red

1971 • 616 citations

The interrelationship between sodium and calcium fluxes across cell membranes

2005 • 598 citations

Estimation of Membrane Potential and pH Difference across the Cristae Membrane of Rat Liver Mitochondria

1969 • 589 citations

Myoplasmic free calcium concentration reached during the twitch of an intact isolated cardiac cell and during calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned cardiac cell from the adult rat or rabbit ventricle.

1981 • 572 citations

Calcium transport in contraction and secretion

1975 • 567 citations

Mitochondrial calcium transport

1982 • 486 citations

Respiration-driven proton translocation in rat liver mitochondria

1967 • 463 citations

Energy-Linked Functions of Mitochondria

1963 • 462 citations

The Ca2+-induced membrane transition in mitochondria

1979 • 442 citations

Hormonal effects on calcium homeostasis in isolated hepatocytes.

1980 • 441 citations

Stoichiometry of Respiratory Stimulation, Accumulation of Ca++ and Phosphate, and Oxidative Phosphorylation in Rat Liver Mitochondria

1964 • 441 citations

Regulation of cellular energy metabolism

1982 • 433 citations

Stoichiometry of sodium-calcium exchange in cardiac sarcolemmal vesicles. Coupling to the sodium pump.

1979 • 407 citations

Energy‐Linked Ion Movements in Mitochondrial Systems

1967 • 403 citations

The Interrelations between the Transport of Sodium and Calcium in Mitochondria of Various Mammalian Tissues

1978 • 402 citations

The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria

1978 • 380 citations

On the role of the calcium transport cycle in heart and other mammalian mitochondria

1980 • 375 citations

EFFECT OF ACTIVE ACCUMULATION OF CALCIUM AND PHOSPHATE IONS ON THE STRUCTURE OF RAT LIVER MITOCHONDRIA

1964 • 374 citations

Regulation of Ca 2+ release from mitochondria by the oxidation-reduction state of pyridine nucleotides

1978 • 364 citations

The release of calcium from heart mitochondria by sodium

1974 • 353 citations

The inhibition of mitochondrial calcium transport by lanthanides and Ruthenium Red

1974 • 351 citations

The Sodium‐Induced Efflux of Calcium from Heart Mitochondria

1976 • 350 citations

Dynamics of energy‐transducing membranes

1975 • 348 citations

A survey of the interaction of calcium ions with mitochondria from different tissues and species

1971 • 339 citations

The effect of ruthenium red on Ca2+ transport and respiration in rat liver mitochondria

1972 • 321 citations

Role of calcium in the hormonal regulation of liver metabolism

1981 • 317 citations

Mitochondrial calcium transport

1980 • 304 citations

Role of calcium ions in the regulation of intramitochondrial metabolism. Effects of Na+, Mg2+ and ruthenium red on the Ca2+-stimulated oxidation of oxoglutarate and on pyruvate dehydrogenase activity in intact rat heart mitochondria

1980 • 292 citations

Cyclic AMP and contractile activity in heart.

1977 • 291 citations

The relationship between mitochondrial membrane permeability, membrane potential, and the retention of Ca2+ by mitochondria.

1980 • 288 citations

The measurement of transmembrane electrochemical proton gradients

1975 • 286 citations

The Calcium‐Induced and Sodium‐Induced Effluxes of Calcium from Heart Mitochondria

1977 • 265 citations

Calcium transport and proton electrochemical potential gradient in mitochondria from guinea-pig cerebral cortex and rat heart

1978 • 264 citations

Membrane bioenergetics

1981 • 258 citations

Regulation of free Ca2+ by liver mitochondria and endoplasmic reticulum.

1980 • 255 citations

Mechanisms for Intracellular Calcium Regulation in Heart

1973 • 253 citations

Vectorial reactions in electron and ion transport in mitochondria and bacteria

1981 • 249 citations

Calcium transients in mammalian ventricular muscle

1980 • 236 citations

Stoichiometry of H+ ejection and Ca2+ uptake coupled to electron transport in rat heart mitochondria.

1978 • 228 citations

Hydroperoxide-induced loss of pyridine nucleotides and release of calcium from rat liver mitochondria.

1980 • 220 citations

Activities of potassium and sodium ions in rabbit heart muscle.

1975 • 214 citations

Evidence for more than one C2+ion transport mechanism in mitochondria

1976 • 211 citations

Studies on alpha-adrenergic activation of hepatic glucose output. The role of mitochondrial calcium release in alpha-adrenergic activation of phosphorylase in perfused rat liver.

1979 • 201 citations

Calcium Ion Distribution in Cytoplasm Visualized by Aequorin: Diffusion in Cytosol Restricted by Energized Sequestering

1975 • 196 citations

Phosphate Transport in Rat Liver Mitochondria

1974 • 192 citations

Intramitochondrial phospholipase activity and the effects of Ca2+ plus N-ethylmaleimide on mitochondrial function.

1979 • 189 citations

The Cycling of Calcium, Sodium, and Protons Across the Inner Membrane of Cardiac Mitochondria

1978 • 188 citations

The Initial Velocities of Calcium Uptake by Rat Liver Mitochondria

1973 • 182 citations

Regulated release of Ca2+ from respiring mitochondria by Ca2+/2H+ antiport.

1979 • 182 citations

Sodium-Calcium Exchange Activity Generates a Current in Cardiac Membrane Vesicles

1980 • 180 citations

Dynamics of energy-transducing membranes

1974 • 175 citations

Inhibition and activation of calcium transport in mitochondria. Effect of lanthanides and local anesthetic drugs

1969 • 170 citations

The Mechanism of Ion Translocation in Mitochondria. 4. Coupling of K+ Efflux with Ca2+ Uptake

1970 • 163 citations

Oscillatory states of mitochondria

1966 • 162 citations

The regulation of brain mitochondrial calcium-ion transport. The role of ATP in the discrimination between kinetic and membrane-potential-dependent calcium-ion efflux mechanisms

1980 • 161 citations

Calcium transport in mitochondria

1970 • 158 citations

Role of calcium ions in the regulation of intramitochondrial metabolism. Properties of the Ca2+-sensitive dehydrogenases within intact uncoupled mitochondria from the white and brown adipose tissue of the rat

1980 • 157 citations

Effects of magnesium, ruthenium red and the antibiotic ionophore A-23187 on initial rates of calcium uptake and release by heart mitochondria

1975 • 155 citations

Selective inhibition of Na+-induced Ca2+ release from heart mitochondria by diltiazem and certain other Ca2+ antagonist drugs.

1982 • 150 citations

Distribution of membrane-confined phospholipases A in the rat hepatocyte

1972 • 147 citations

Charge movements during the Na+-Ca2+ exchange in heart sarcolemmal vesicles.

1980 • 145 citations

Determination of the matrix free Ca2+ concentration and kinetics of Ca2+ efflux in liver and heart mitochondria.

1982 • 144 citations

Kinetics of calcium(2+) ion carrier in rat liver mitochondria

1979 • 143 citations

The calcium conductance of the inner membrane of rat liver mitochondria and the determination of the calcium electrochemical gradient

1976 • 139 citations

A kinetic analysis of the effects of adrenaline on calcium distribution in isolated rat liver parenchymal cells

1981 • 136 citations

Cyclic AMP stimulation of calcium efflux from kidney, liver, and heart mitochondria

1974 • 133 citations

A Kinetic Study of the Energy‐Linked Influx of Ca2+ into Heart Mitochondria

1976 • 131 citations

Evidence for mitochondrial localization of the hormone-responsive pool of Ca2+ in isolated hepatocytes.

1979 • 128 citations

The uptake and extrusion of monovalent cations by isolated heart mitochondria

1976 • 127 citations

Energy relationships between cytosolic metabolism and mitochondrial respiration in rat heart

1978 • 127 citations

Isolation of a soluble Ca2+ binding glycoprotein from ox liver mitochondria

1972 • 125 citations

The Role of Phosphate in the Regulation of the Independent Calcium‐Efflux Pathway of Liver Mitochondria

1982 • 124 citations

Intracellular calcium buffering capacity in isolated squid axons.

1977 • 122 citations

Respiration-Linked H+ Translocation in Mitochondria: Stoichiometry and Mechanism

1980 • 118 citations

Disequilibrium between steady-state Ca2+ ion accumulation ratio and membrane potential in mitochondria. Pathway and role of Ca2+ ion efflux

1977 • 118 citations

Effects of Beta- and Alpha-Adrenoceptor Activators and Adrenergic Transmitter Releasing Agents on the Mechanical Activity of the Heart

1980 • 116 citations

Effect of ATP on the Calcium Efflux in Dialyzed Squid Giant Axons

1974 • 114 citations

Na+-Ca2+ exchange is affected by membrane potential in cardiac sarcolemmal vesicles.

1980 • 113 citations

Calcium metabolism in rat hepatocytes

1978 • 111 citations

The Energy‐State of Mitochondria during the Transport of Ca2+

1980 • 110 citations

A procedure for the rapid preparation of mitochondria from rat liver

1982 • 106 citations

Uptake and Release of Bivalent Cations in Mitochondria1 1Dedicated to Eva.

1980 • 101 citations

Energy Dissipation by Calcium Recycling and the Efficiency of Calcium Transport in Rat-Liver Mitochondria

1974 • 99 citations

Partial purification and characterization of the phospholipase A2 from rat liver mitochondria

1971 • 99 citations

The control of Ca2+ release from heart mitochondria.

1981 • 95 citations

Alpha-adrenergic receptors in rat myocardium. Identification by binding of [3H]dihydroergocryptine.

1978 • 95 citations

The nature of the calcium ion efflux induced in rat liver mitochondria by the oxidation of endogenous nicotinamide nucleotides

1980 • 94 citations

Stable changes to calcium fluxes in mitochondria isolated from rat livers perfused with α-adrenergic agonists and with glucagon

1980 • 93 citations

Ion transport in heart mitochondria. XIII. The effect of ethylenediaminetetraacetate on monovalent ion uptake

1968 • 92 citations

Changes in membrane potential during calcium ion influx and efflux across the mitochondrial membrane

1978 • 89 citations

Effect of pH and Ca2+ on the retention of Ca2+ by rat liver mitochondria

1978 • 85 citations

Hormonal regulation of liver mitochondrial pyruvate carrier in relation to gluconeogenesis and lipogenesis

1976 • 84 citations

Respiration-dependent efflux of magnesium ions from heart mitochondria

1976 • 84 citations

Effects of glucagon and N6O2′-dibutyryladenosine 3′:5′-cyclic monophosphate on calcium transport in isolated rat liver mitochondria

1978 • 83 citations

Intramitochondrial and extramitochondrial free calcium ion concentrations of suspensions of heart mitochondria with very low, plausibly physiological, contents of total calcium

1982 • 82 citations

An insoluble Ca2+-binding factor from rat liver mitochondria

1972 • 81 citations

Synthesis and characterization of phosphocitric acid, a potent inhibitor of hydroxylapatite crystal growth

1980 • 78 citations

ATP Prevents both Hydroperoxide‐Induced Hydrolysis of Pyridine Nucleotides and Release of Calcium in Rat Liver Mitochondria

1981 • 75 citations

Correlated Effluxes of Adenine Nucleotides, Mg2+ and Ca2+ Induced in Rat‐Liver Mitochondria by External Ca2+ and Phosphate

1981 • 75 citations

Proton electrochemical potential in steady state rat liver mitochondria

1977 • 75 citations

Calcium uptake by two preparations of mitochondria from heart

1980 • 74 citations

Na+ releases Ca2+ from liver, kidney and lung mitochondria

1980 • 74 citations

Regulation of Ca2+ Efflux from Kidney and Liver Mitochondria by Unsaturated Fatty Acids and Na+ Ions

1979 • 72 citations

THE ACCUMULATION OF DIVALENT IONS BY ISOLATED MITOCHONDRIA

1963 • 70 citations

A comparative study of cytochrome ratios in mitochondria from organs of the rat, chicken, and guinea pig

1968 • 69 citations

Effect of micromolar concentrations of free Ca2+ ions on pyruvate dehydrogenase interconversion in intact rat heart mitochondria

1981 • 69 citations

Effect of micromolar concentrations of free calcium ions on the reduction of heart mitochondrial NAD(P) by 2-oxoglutarate

1981 • 68 citations

The activation of pyruvate dehydrogenase in the perfused rat heart by adrenaline and other inotropic agents

1981 • 68 citations

Blockade of hepatic α‐adrenergic receptors and responses by chlorpromazine and trifluoperazine

1981 • 68 citations

Evidence for the existence of regulatory sites for Ca2+ on the Na+/Ca2+ carrier of cardiac mitochondria

1982 • 64 citations

The lanthanide‐sensitive calcium phosphate porter of rat liver mitochondria

1977 • 64 citations

Ruthenium red sensitive and insensitive calcium transport in rat liver and Ehrlich ascites tumor cell mitochondria

1978 • 62 citations

Effects of N-ethylmaleimide on the limited uptake of Ca2+, Mn2+, and Sr2+ by rat liver mitochondria.

1978 • 62 citations

The resolution of calcium fluxes in heart and liver mitochondria using the lanthanide series

1979 • 60 citations

Retention of Ca2+ by rat liver and rat heart mitochondria: Effect of phosphate, Mg2+, and NAD(P) redox state

1980 • 59 citations

State and distribution of potassium and sodium ions in frog skeletal muscle

1974 • 56 citations

Efflux of Ca2+andMn2+ from rat liver mitochondria

1978 • 53 citations

Modulation of Ca2+ efflux from heart mitochondria

1979 • 53 citations

Stimulation of the respiratory chain of rat liver mitochondria between cytochrome c1 and cytochrome c by glucagon treatment of rats

1978 • 52 citations

The Ca2+-Na+ antiporter of heart mitochondria operates electroneutrally

1980 • 51 citations

The electric charge stoichiometry of respiration-dependent Ca2+ uptake by mitochondria.

1979 • 48 citations

Sodium-induced calcium release from mitochondria in brown adipose tissue.

1979 • 48 citations

Specific inhibition of mitochondrial Ca2+ transport by antibodies directed to the Ca2+ -binding glycoprotein

1976 • 47 citations

Calcium Ions, Hormones and Mitochondrial Metabolism

1981 • 47 citations

Regulation of mitochondrial metabolism by specific cellular substances. II. The nature of stimulation of mitochondrial glutamate metabolism by a cytoplasmic component

1969 • 46 citations

The Ca2+ and Mg2+ dependence of Ca2+ uptake and respiratory function of porcine heart mitochondria. Probable physiological significance during the cardiac contraction-relaxation cycle.

1982 • 46 citations

Dissociation between mitochondria calcium ion release and pyridine nucleotide oxidation.

1980 • 46 citations

The Role of Inorganic Phosphate in the Release of Ca2+ from Rat‐Liver Mitochondria

1980 • 45 citations

Transport and metabolism of thiamin in isolated rat hepatocytes.

1979 • 45 citations

Evidence for β-adrenergic activation of Na+-dependent efflux of Ca2+ from isolated liver mitochondria

1982 • 44 citations

Steady state regulation of extramitochondrial Ca2+ by rat liver mitochondria. Effects of Mg2+ and ATP

1980 • 42 citations

Calcium carrier and the “high affinity calcium binding site” in mitochondria

1969 • 42 citations

The transport of Ca2+ in a purified population of inside‐out vesicles from rat liver mitochondria

1979 • 41 citations

The α-adrenergic-mediated activation of Ca2+ influx into cardiac mitochondria. A possible mechanism for the regulation of intramitochondrial free CA2+

1981 • 39 citations

Alpha adrenergic involvement in heart metabolism: effects on adenosine cyclic 3',5'-monophosphate, adenosine cyclic 3',5'-monophosphate-dependent protein kinase, guanosine cyclic 3',5'-monophosphate, and glucose transport.

1977 • 38 citations

The activation of Na+-dependent efflux of Ca2+ from liver mitochondria by glucagon and β-adrenergic agonists

1983 • 38 citations

Ca2+-regulated release of an ATPase inhibitor protein from submitochondrial particles derived from skeletal muscles of the rat.

1980 • 38 citations

Rapid action of glucagon on hepatic mitochondrial calcium metabolism and respiratory rates

1980 • 37 citations

ADP and Mg2+ requirement for Ca2+ accumulation by hog heart mitochondria. Correlation with energy coupling

1974 • 36 citations

The effect of phosphoenolpyruvate on the retention of calcium by liver mitochondria

1978 • 36 citations

Stimulation of calcium-ion efflux from liver mitochondria by sodium ions and its response to ADP and energy state

1981 • 35 citations

Parallel efflux of Ca2+ and Pi in energized rat liver mitochondria

1981 • 35 citations

Isolation and properties of Ca2+-transporting glycoprotein and peptide from beef heart mitochondria

1982 • 35 citations

The stimulation of the release of Ca2+ from mitochondria by sodium ions and its inhibition

1982 • 35 citations

The effect of inorganic phosphate on calcium influx into rat heart mitochondria

1978 • 31 citations

ΔpH Induced Calcium Fluxes in Rat Liver Mitochondria

1979 • 30 citations

Synergic action of calcium ions and diamide on mitochondrial swelling

1975 • 30 citations

The activation by potassium of the sodium—calcium carrier of cardiac mitochondria

1980 • 29 citations

Effects of glucagon and Na+ on the control of extramitochondrial free Ca2+ concentration by mitochondria from liver and heart

1980 • 27 citations

The Ca2+-Binding Glycoprotein as the Site of Metabolic Regulation of Mitochondrial Ca2+ Movements

1980 • 27 citations

Use of the coulombic interactions of the lanthanide series to identify two classes of Ca2+ binding sites in mitochondria

1977 • 27 citations

Studies on heart sarcolemma: vesicles of opposite orientation and the effect of ATP on the Na+/Ca2+ exchanger

1981 • 27 citations

Charge transfer during valinomycin‐induced Ca2+ uptake in rat liver mitochondria

1978 • 26 citations

The influence of external cations and membrane potential on Ca-activated Na efflux in Myxicola giant axons.

1978 • 25 citations

The ability of the mitochondrial Ca2+-binding glycoprotein to restore Ca2+ transport in glycoprotein-depleted rat liver mitochondria

1979 • 24 citations

Reversal by uncouplers of oxidative phosphorylation and by Ca2+ of the inhibition of mitochondrial ATPase activity by the ATPase inhibitor protein of rat skeletal muscle.

1981 • 24 citations

Phosphate transport in rat liver mitochondria. Properties of a Ca2+-activated uptake process in inverted inner membrane vesicles.

1979 • 24 citations

Studies on the binding of nucleotides by rat brain hexokinase

1982 • 23 citations

The electrophoretic properties of a Ca2+ carrier isolated from calf heart inner mitochondrial membrane.

1980 • 22 citations

Effects of Monovalent Cations on Ca(2+) Transport in Mitochondria; A Comparison between Brown Fat and Liver Mitochondria from Rat.

1980 • 22 citations

Epinephrine regulation of phosphofructokinase in perfused rat heart. A calcium ion-dependent mechanism mediated via alpha-receptors.

1982 • 21 citations

Effect of ruthenium red on calcium efflux from rat liver mitochondria

1980 • 21 citations

Calcium‐proton exchange in cardiac and liver mitochondria

1979 • 20 citations

Evidence that glucagon acts on the liver to decrease mitochondrial calcium stores

1983 • 18 citations

Adenosine 3′ : 5′-Cyclic Monophosphate Stimulation of Calcium Efflux from Mitochondria

1974 • 18 citations

The sodium ion/calcium ion cycle of cardiac mitochondria

1980 • 17 citations

Immunochemical evidence of the independence of the Ca2+/Na2+ antiporter and electrophoretic Ca2+ uniporter in heart mitochondria

1981 • 15 citations

Stimulation of calcium efflux from rat liver mitochondria by adenosine 3′5′ cyclic monophosphate

1980 • 13 citations

Regulation of Ca++ efflux from kidney and liver mitochondria by unsaturated fatty acids and Na+ ions

1979 • 9 citations

Role of cyclic nucleotides in the regulation of mitochondrial calcium uptake and efflux kinetics

1977 • 7 citations

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