Differential role of sarcolemmal and mitochondrial K_ATPchannels in adenosine-enhanced ischemic preconditioning

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium.

1986 • 7,740 citations

ATP-regulated K+ channels in cardiac muscle

1983 • 2,350 citations

Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.

1991 • 1,346 citations

Cardioprotective Effect of Diazoxide and Its Interaction With Mitochondrial ATP-Sensitive K ⁺ Channels

1997 • 1,032 citations

Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs.

1992 • 961 citations

Mitochondrial ATP-Dependent Potassium Channels

1998 • 825 citations

Sarcolemmal Versus Mitochondrial ATP-Sensitive K ⁺ Channels and Myocardial Preconditioning

1999 • 484 citations

Adenosine triphosphate-sensitive potassium channels in the cardiovascular system

1991 • 440 citations

Modulation of Mitochondrial ATP-Dependent K ⁺ Channels by Protein Kinase C

1998 • 368 citations

Cardiac ATP-sensitive K+ channels: regulation by intracellular nucleotides and K+ channel-opening drugs

1995 • 309 citations

Preconditioning: state of the art myocardial protection

1993 • 301 citations

Blockade of ischaemic preconditioning in dogs by the novel ATP dependent potassium channel antagonist sodium 5-hydroxydecanoate

1992 • 282 citations

Ischemic preconditioning in rats: role of mitochondrial K_ATPchannel in preservation of mitochondrial function

2000 • 228 citations

Rat and rabbit heart infarction: effects of anesthesia, perfusate, risk zone, and method of infarct sizing

1994 • 186 citations

Limitation of infarct size in the rabbit by ischaemic preconditioning is reversible with glibenclamide

1993 • 165 citations

Adenosine and the anti-infarct effects of preconditioning

1993 • 160 citations

Cardioprotection provided by adenosine receptor activation is abolished by blockade of the KATP channel

1994 • 158 citations

Cardioprotection with the KATP Opener Cromakalim Is Not Correlated with Ischemic Myocardial Action Potential Duration

1995 • 148 citations

Ischaemic preconditioning in a model of global ischaemia: Infarct size limitation, but no reduction of stunning

1995 • 138 citations

Pharmacology of ATP-sensitive potassium channel (K<SUB>ATP</SUB>) openers in models of myocardial ischemia and reperfusion

1997 • 110 citations

Tumor Necrosis Factor-α Is Expressed in Donor Heart and Predicts Right Ventricular Failure After Human Heart Transplantation

2000 • 97 citations

HMR 1883, a novel cardioselective inhibitor of the ATP-sensitive potassium channel. Part II: effects on susceptibility to ventricular fibrillation induced by myocardial ischemia in conscious dogs.

1998 • 95 citations

Activation of cardiac ATP-sensitive K+ current during hypoxia: correlation with tissue ATP levels

1991 • 94 citations

HMR 1883, a novel cardioselective inhibitor of the ATP-sensitive potassium channel. Part I: effects on cardiomyocytes, coronary flow and pancreatic beta-cells.

1998 • 93 citations

ATP-sensitive potassium channel mediates delayed ischemic protection by heat stress in rabbit heart

1997 • 88 citations

A1 Receptor mediated myocardial infarct size reduction by endogenous adenosine is exerted primarily during ischaemia

1994 • 82 citations

Ketamine-xylazine anaesthesia permits a KATPchannel antagonist to attenuate preconditioning in rabbit myocardium

1994 • 74 citations

Protection from ischaemic-reperfusion injury with adenosine pretreatment is reversed by inhibition of ATP sensitive potassium channels

1993 • 68 citations

Pharmacology of ATP-sensitive potassium channel (K_ATP) openers in models of myocardial ischemia and reperfusion

1997 • 55 citations

S-T segment voltage during sequential coronary occlusions is an unreliable marker of preconditioning

1999 • 48 citations

Contractile Function and Ca<sup>2+</sup> Transport System of Myocardium in Ageing

1988 • 45 citations

Myocardial mitochondrial calcium accumulation modulates nuclear calcium accumulation and DNA fragmentation

1995 • 38 citations

Adenosine-enhanced ischemic preconditioning provides enhanced cardioprotection in the aged heart

1998 • 37 citations

Anti-Stunning and Anti-Infarct Effects of Adenosine-Enhanced Ischemic Preconditioning

2000 • 36 citations

Signal Transduction by Intramitochondrial Ca2+ in Mammalian Energy Metabolism

1994 • 35 citations

Glibenclamide, a Blocker of ATP-Sensitive Potassium Channels, Abolishes Infarct Size Limitation by Preconditioning in Rabbits Anesthetized with Xylazine/Pentobarbital but Not with Pentobarbital Alone

1995 • 33 citations

Magnesium Cardioplegia Enhances mRNA Levels and the Maximal Velocity of Cytochrome Oxidase I in the Senescent Myocardium During Global Ischemia

1995 • 29 citations

Adenosine-enhanced ischemic preconditioning provides enhanced postischemic recovery and limitation of infarct size in the rabbit heart

1998 • 29 citations

Blockade of the KATP-channel by glibenclamide aggravates ischemic injury, and counteracts ischemic preconditioning

1996 • 25 citations

Adenosine-enhanced ischemic preconditioning decreases infarct in the regional ischemic sheep heart

1998 • 23 citations

Adenosine-enhanced ischemic preconditioning provides myocardial protection equal to that of cold blood cardioplegia

1999 • 17 citations

Functional Modulation of Cardiac ATP-Sensitive K⁺ Channels

1998 • 15 citations

Endothelin Receptors and Angiotensin II Receptors in Tumor Tissue

1998 • 10 citations

The adenosine-triphosphate–sensitive potassium-channel opener pinacidil is effective in blood cardioplegia

1998 • 8 citations