Exocytosis in adrenal chromaffin cells.

A model for receptor-regulated calcium entry

1986 • 2,535 citations

Calcium ions, active zones and synaptic transmitter release

1988 • 609 citations

Compartmentalization of the submembrane calcium activity during calcium influx and its significance in transmitter release

1985 • 609 citations

Calcium-dependence of catecholamine release from bovine adrenal medullary cells after exposure to intense electric fields

1982 • 500 citations

Aggregation of chromaffin granules by calpactin at micromolar levels of calcium

1988 • 443 citations

Identification and purification of an adrenal medullary protein (synexin) that causes calcium-dependent aggregation of isolated chromaffin granules.

1978 • 396 citations

Catecholamine secretion from digitonin-treated adrenal medullary chromaffin cells.

1983 • 338 citations

Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases.

1988 • 332 citations

A role for calpactin in calcium-dependent exocytosis in adrenal chromaffin cells

1989 • 321 citations

Control of exocytosis in adrenal chromaffin cells

1991 • 250 citations

Localization and heterogeneity of agonist-induced changes in cytosolic calcium concentration in single bovine adrenal chromaffin cells from video imaging of fura-2.

1989 • 236 citations

Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolin.

1991 • 223 citations

Protein kinase C inhibitor proteins

1990 • 213 citations

Exol and Exo2 proteins stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells

1992 • 185 citations

Distribution of two distinct Ca2+ -ATPase-like proteins and their relationships to the agonist-sensitive calcium store in adrenal chromaff in cells

1989 • 185 citations

Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry.

1990 • 179 citations

Nicotine‐evoked disassembly of cortical actin filaments in adrenal chromaffin cells

1986 • 171 citations

Cellular responses to Ca2+ from extracellular and intracellular sources are different as shown by simultaneous measurements of cytosolic Ca2+ and secretion from bovine chromaffin cells.

1989 • 136 citations

Simultaneous measurements of cytosolic calcium and secretion in single bovine adrenal chromaffin cells by fluorescent imaging of fura-2 in cocultured cells.

1989 • 127 citations

Changes in the state of actin during the exocytotic reaction of permeabilized rat mast cells.

1990 • 124 citations

Calcium-dependent and calcium-independent exocytosis

1989 • 124 citations

Loss of proteins from digitonin-permeabilized adrenal chromaffin cells essential for exocytosis.

1987 • 124 citations

Introduction of Macromolecules into Bovine Adrenal Medullary Chromaffin Cells and Rat Pheochromocytoma Cells (PC12) by Permeabilization with Streptolysin O: Inhibitory Effect of Tetanus Toxin on Catecholamine Secretion

1989 • 112 citations

Spatial localization of the stimulus‐induced rise in cytosolic Ca²⁺ in bovine adrenal chromaffin cells

1989 • 112 citations

Chromaffin cell calcium channel kinetics measured isotopically through fast calcium, strontium, and barium fluxes.

1987 • 108 citations

The control of cytoskeletal actin and exocytosis in intact and permeabilized adrenal chromaffin cells: role of calcium and protein kinase C

1989 • 104 citations

Cyclic AMP inhibits both nicotine-induced actin disassembly and catecholamine secretion from bovine adrenal chromaffin cells.

1987 • 99 citations

cAMP and Ca(2+)-mediated secretion in parotid acinar cells is associated with reversible changes in the organization of the cytoskeleton.

1992 • 97 citations

A major role for protein kinase C in calcium‐activated exocytosis in permeabilised adrenal chromaffin cells

1988 • 97 citations

Visualization of the exocytosis/endocytosis secretory cycle in cultured adrenal chromaffin cells.

1983 • 96 citations

Evidence implicating protein kinase C in exocytosis from electropermeabilized bovine chromaffin cells

1988 • 89 citations

Activation of protein kinase C is not required for exocytosis from bovine adrenal chromaffin cells. The effects of protein kinase C(19-31), Ca/CaM kinase II(291-317), and staurosporine.

1990 • 87 citations

A comparison of bradykinin, angiotensin II and muscarinic stimulation of cultured bovine adrenal chromaffin cells

1989 • 84 citations

Bovine adrenal chromaffin cells contain an inositol 1,4,5-trisphosphate-insensitive but caffeine-sensitive Ca2+ store that can be regulated by intraluminal free Ca2+

1991 • 81 citations

Characterisation of Distinct Inositol 1,4,5‐Trisphosphate‐Sensitive and Caffeine‐Sensitive Calcium Stores in Digitonin‐Permeabilised Adrenal Chromaffin Cells

1991 • 77 citations

Interaction between protein kinase C and Exo1 (14–3–3 protein) and its relevance to exocytosis in permeabilized adrenal chromaffin cells

1992 • 77 citations

Ca2+ influx induced by the Ca2+-ATPase inhibitors 2,5-di-(t-butyl)-1,4-benzohydroquinone and thapsigargin in bovine adrenal chromaffin cells

1992 • 69 citations

Exocytotic exposure and retrieval of membrane antigens of chromaffin granules: quantitative evaluation of immunofluorescence on the surface of chromaffin cells.

1984 • 67 citations

The role of caffeine-sensitive Ca2+ stores in agonist- and inositol 1,4,5-trisphosphate-induced Ca2+ release from bovine adrenal chromaffin cells

1991 • 64 citations

The caffeine‐sensitive Ca²⁺ store in bovine adrenal chromaffin cells; an examination of its role in triggering secretion and Ca²⁺ homeostasis

1990 • 59 citations

A Molecular Basis for Synexin-Driven, Calcium-Dependent Membrane Fusion

1988 • 50 citations

Relationship between arachidonic acid release and Ca2+-dependent exocytosis in digitonin-permeabilized bovine adrenal chromaffin cells

1990 • 42 citations

The inositol 1,4,5-trisphosphate-forming agonist histamine activates a ryanodine-sensitive Ca2+ release mechanism in bovine adrenal chromaffin cells.

1991 • 41 citations

Agonist-dependent patterns of cytosolic Ca2+ changes in single bovine adrenal chromaffin cells: relationship to catecholamine release.

1990 • 37 citations

Evidence for a role of calpactin in calcium-dependent exocytosis

1990 • 24 citations

Mechanisms Involved in Calcium‐Dependent Exocytosisa

1991 • 19 citations

A distinct 2,5‐di‐(tert‐butyl)‐1,4‐benzohydroquinone‐sensitive calcium store in bovine adrenal chromaffin cells

1991 • 18 citations

Histamine stimulates exocytosis in a sub-population of bovine adrenal chromaffin cells

1992 • 11 citations