An Allelic Association Implicates Myeloperoxidase in the Etiology of Acute Promyelocytic Leukemia

Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia

1985 • 2,981 citations

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1988 • 2,380 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

1994 • 1,274 citations

All-trans-Retinoic Acid in Acute Promyelocytic Leukemia

1997 • 1,090 citations

Multiple Sclerosis: A Coordinated Immunological Attack against Myelin in the Central Nervous System

1996 • 903 citations

THE DEVELOPMENT OF NEUTROPHILIC POLYMORPHONUCLEAR LEUKOCYTES IN HUMAN BONE MARROW

1971 • 870 citations

Myeloperoxidase-Halide-Hydrogen Peroxide Antibacterial System

1968 • 840 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

1994 • 798 citations

Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia.

1993 • 658 citations

An Alu Element in the Myeloperoxidase Promoter Contains a Composite SP1-Thyroid Hormone-Retinoic Acid Response Element

1996 • 415 citations

All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship

1990 • 390 citations

Spin trapping evidence for myeloperoxidase-dependent hydroxyl radical formation by human neutrophils and monocytes.

1992 • 233 citations

Identification of a New Subclass of Alu DNA Repeats Which Can Function as Estrogen Receptor-dependent Transcriptional Enhancers

1995 • 226 citations

Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Converts Low Density Lipoprotein Cholesterol into a Family of Chlorinated Sterols

1996 • 219 citations

Expression of the neutrophil elastase gene during human bone marrow cell differentiation.

1989 • 190 citations

Myeloperoxidase: its structure and expression during myeloid differentiation

1985 • 184 citations

The consensus sequence of a major Alu subfamily contains a functional retinoic acid response element.

1995 • 176 citations

High frequency of acute promyelocytic leukemia among Latinos with acute myeloid leukemia [see comments]

1996 • 176 citations

Characterization of cDNA clones for human myeloperoxidase: Predicted amino acid sequence and evidence for multiple mRNA species

1987 • 169 citations

High frequency of acute promyelocytic leukemia among Latinos with acute myeloid leukemia [see comments]

1996 • 116 citations

Chromosomal gene structure of human myeloperoxidase and regulation of its expression by granulocyte colony-stimulating factor.

1987 • 113 citations

Regulation of gene expression of myeloperoxidase during myeloid differentiation

1988 • 110 citations

p-Hydroxyphenylacetaldehyde Is the Major Product of L-Tyrosine Oxidation by Activated Human Phagocytes

1996 • 103 citations

Myeloperoxidase-enhanced formation of (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a] pyrene adducts in lung tissue in vitro: a role of pulmonary inflammation in the bioactivation of a procarcinogen

1992 • 102 citations

Disturbed myeloperoxidase-dependent activity of neutrophils in cystic fibrosis homozygotes and heterozygotes, and its correction by amiloride.

1996 • 102 citations

NB4 cells show bilineage potential and an aberrant pattern of neutrophil secondary granule protein gene expression

1994 • 95 citations

Viricidal effect of polymorphonuclear leukocytes on human immunodeficiency virus-1. Role of the myeloperoxidase system.

1992 • 93 citations

Hereditary myeloperoxidase deficiency due to a missense mutation of arginine 569 to tryptophan.

1994 • 88 citations

Hypochlorous acid/N-chloramines are naturally produced DNA repair inhibitors

1996 • 87 citations

Regulation of myeloperoxidase gene expression during differentiation of human myeloid leukemia HL-60 cells.

1984 • 78 citations

The role of peroxidase-catalyzed activation of aromatic amines in breast cancer

1996 • 77 citations

Effect of the R569W Missense Mutation on the Biosynthesis of Myeloperoxidase

1996 • 75 citations

NK cell‐mediated killing of AML blasts: role of histamine, monocytes and reactive oxygen metabolites

1996 • 68 citations

Multiple species of myeloperoxidase messenger RNAs produced by alternative splicing and differential polyadenylation

1988 • 68 citations

Sequence comparison of putative regulatory DNA of the 5' flanking region of the myeloperoxidase gene in normal and leukemic bone marrow cells.

1993 • 63 citations

Hypochlorous acid potentiates hydrogen peroxide-mediated DNA-strand breaks in human mononuclear leucocytes

1992 • 57 citations

The localization of the human myeloperoxidase gene is in close proximity to the translocation breakpoint in acute promyelocytic leukemia.

1987 • 48 citations

Multilineage phenotypes of interleukin-3-dependent progenitor cells

1992 • 46 citations

Myeloperoxidase (MPO) gene mutation in hereditary MPO deficiency

1994 • 43 citations

Transcriptional regulation of myeloperoxidase gene expression in myeloid leukemia HL-60 cells during differentiation into granulocytes and macrophages

1988 • 41 citations

Mutagenic potential of toluidine blue evaluated in the Ames test

1992 • 40 citations

Human myeloperoxidase gene expression in acute leukemia

1989 • 40 citations

Human myeloperoxidase gene expression in acute leukemia

1989 • 37 citations

Complete nucleotide sequence of the human myeloperoxidase gene

1989 • 36 citations

A switch toward demethylation is associated with the expression of myeloperoxidase in acute myeloblastic and promyelocytic leukemias

1992 • 31 citations

Identification of transcriptional cis-elements in introns 7 and 9 of the myeloperoxidase gene

1993 • 27 citations

Cis-elements in the promoter region of the human myeloperoxidase (MPO) gene.

1996 • 23 citations

Localization of the Human Estrogen-Responsive Finger Protein (EFP) Gene (ZNF147) within a YAC Contig Containing the Myeloperoxidase (MPO) Gene

1995 • 13 citations

Multilineage phenotypes of interleukin-3-dependent progenitor cells

1992 • 7 citations