Cortical Actin Structures and Their Relationship to Mammalian Cell Movements

Principles of Polymer Chemistry.

1954 • 16,197 citations

Principles of polymer chemistry

1995 • 15,622 citations

The Mechanism of Muscular Contraction

1969 • 1,928 citations

Microfilaments in Cellular and Developmental Processes

1971 • 1,563 citations

Silicone Rubber Substrata: A New Wrinkle in the Study of Cell Locomotion

1980 • 1,333 citations

Actin And Myosin And Cell Movemen

1974 • 1,018 citations

A 130K protein from chicken gizzard: Its localization at the termini of microfilament bundles in cultured chicken cells

1979 • 794 citations

Control of cytoplasmic actin gel–sol transformation by gelsolin, a calcium-dependent regulatory protein

1979 • 782 citations

Structural interaction of cytoskeletal components

1981 • 766 citations

Mechanism of action of cytochalasin B on actin

1980 • 732 citations

Actin Antibody: The Specific Visualization of Actin Filaments in Non-Muscle Cells

1974 • 721 citations

Mechanism of abnormal bleeding in patients undergoing cardiopulmonary bypass: acquired transient platelet dysfunction associated with selective alpha-granule release.

1980 • 677 citations

Actin polymerizability is influenced by profilin, a low molecular weight protein in non-muscle cells

1977 • 673 citations

Filament organization revealed in platinum replicas of freeze-dried cytoskeletons.

1980 • 662 citations

Organization of an actin filament-membrane complex. Filament polarity and membrane attachment in the microvilli of intestinal epithelial cells.

1975 • 615 citations

Thermodynamics of the polymerization of protein

1975 • 596 citations

Thermodynamics of the Polymerization of Protein

1976 • 580 citations

The molecular structure of human erythrocyte spectrin

1979 • 539 citations

Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes.

1980 • 502 citations

Fodrin: axonally transported polypeptides associated with the internal periphery of many cells.

1981 • 480 citations

Cytochalasin D inhibits actin polymerization and induces depolymerization of actin filaments formed during platelet shape change

1981 • 460 citations

Actin, alpha-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells.

1976 • 454 citations

Villin is a major protein of the microvillus cystoskeleton which binds both G and F actin in a calcium-dependent manner

1980 • 444 citations

Cytochalasins block actin filament elongation by binding to high affinity sites associated with F-actin.

1980 • 430 citations

The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes

1979 • 423 citations

Microinjection and localization of a 130K protein in living fibroblasts: a relationship to actin and fibronectin

1980 • 406 citations

Isolation and properties of actin, myosin, and a new actinbinding protein in rabbit alveolar macrophages.

1975 • 388 citations

International Cell Biology 1980–1981

1981 • 363 citations

Co-existence of vinculin and a vinculin-like protein of higher molecular weight in smooth muscle.

1982 • 343 citations

Brain spectrin, a membrane-associated protein related in structure and function to erythrocyte spectrin

1982 • 341 citations

Actin Filament Stress Fibers in Vascular Endothelial Cells in Vivo

1983 • 334 citations

The visualization of actin filament polarity in thin sections. Evidence for the uniform polarity of membrane-associated filaments.

1978 • 329 citations

THE POLYMERIZATION OF ACTIN: ITS ROLE IN THE GENERATION OF THE ACROSOMAL PROCESS OF CERTAIN ECHINODERM SPERM

1973 • 326 citations

Actin in Dividing Cells: Contractile Ring Filaments Bind Heavy Meromyosin

1973 • 319 citations

Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells.

1975 • 317 citations

Correlation between effects of 24 different cytochalasins on cellular structures and cellular events and those on actin in vitro

1982 • 316 citations

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures.

1980 • 306 citations

Identification and organization of the components in the isolated microvillus cytoskeleton.

1979 • 303 citations

Direct measurement of actin polymerization rate constants by electron microscopy of actin filaments nucleated by isolated microvillus cores.

1981 • 298 citations

Nonerythrocyte spectrins: actin-membrane attachment proteins occurring in many cell types

1982 • 295 citations

Cytochalasin inhibits the rate of elongation of actin filament fragments

1979 • 295 citations

Mechanism of retraction of the trailing edge during fibroblast movement.

1981 • 290 citations

Interactions of actin, myosin, and a new actin-binding protein of rabbit pulmonary macrophages. II. Role in cytoplasmic movement and phagocytosis.

1976 • 289 citations

The Relation of Muscle Biochemistry to Muscle Physiology

1980 • 286 citations

An F-actin- and calmodulin-binding protein from isolated intestinal brush borders has a morphology related to spectrin

1982 • 276 citations

Villin: The major microfilament-associated protein of the intestinal microvillus

1979 • 270 citations

Human platelet myosin. II. In vitro assembly and structure of myosin filaments.

1975 • 269 citations

Tropomyosin binding to F‐actin protects the F‐actin from disassembly by brain actin‐depolymerizing factor (ADF)

1982 • 263 citations

Ca2+ control of actin gelation. Interaction of gelsolin with actin filaments and regulation of actin gelation.

1980 • 260 citations

Substoichiometric concentrations of cytochalasin D inhibit actin polymerization. Additional evidence for an F-actin treadmill.

1979 • 259 citations

Non-muscle α-actinins are calcium-sensitive actin-binding proteins

1981 • 257 citations

Mechanism of action of cytochalasin: evidence that it binds to actin filament ends.

1981 • 256 citations

Comparative biochemistry of non-muscle actins.

1977 • 255 citations

Polymerization of actin. IV. Role of Ca++ and H+ in the assembly of actin and in membrane fusion in the acrosomal reaction of echinoderm sperm

1978 • 255 citations

In vitro formation of a complex between cytoskeletal proteins of the human erythrocyte

1979 • 254 citations

α-Actinin, a New Structural Protein from Striated Muscle

1965 • 252 citations

Identification of gelsolin, a Ca2+-dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues.

1981 • 246 citations

Relation between cell activity and the distribution of cytoplasmic actin and myosin.

1981 • 236 citations

Cytochalasin B and the structure of actin gels

1979 • 234 citations

Regulation of Smooth Muscle Actomyosin

1981 • 234 citations

Changes in the cytoskeletal structure of human platelets following thrombin activation.

1981 • 232 citations

Chemistry of Muscle Contraction

1972 • 231 citations

Interaction of alpha-actinin and vinculin with actin: opposite effects on filament network formation.

1981 • 230 citations

Erythroid spectrin, brain fodrin, and intestinal brush border proteins (TW-260/240) are related molecules containing a common calmodulin-binding subunit bound to a variant cell type-specific subunit.

1982 • 228 citations

Partial purification and characterization of an actin depolymerizing factor from brain

1980 • 222 citations

Ca2+ control of actin filament length. Effects of macrophage gelsolin on actin polymerization.

1981 • 217 citations

Spectrin plus band 4.1 cross-link actin. Regulation by micromolar calcium.

1980 • 216 citations

F-actin binding and bundling properties of fimbrin, a major cytoskeletal protein of microvillus core filaments.

1981 • 214 citations

Actin Amino-Acid Sequences. Comparison of Actins from Calf Thymus, Bovine Brain, and SV40-Transformed Mouse 3T3 Cells with Rabbit Skeletal Muscle Actin

1978 • 211 citations

Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking

1985 • 208 citations

A tropomyosin-like protein from human platelets

1972 • 206 citations

Evidence for biased bidirectional polymerization of actin filaments using heavy meromyosin prepared by an improved method.

1975 • 204 citations

Identification of a spectrin-like protein in nonerythroid cells.

1981 • 198 citations

Transformation and motility of human platelets: details of the shape change and release reaction observed by optical and electron microscopy.

1979 • 197 citations

Shape and Movement of Mesenchyme Cells as Functions of the Physical Structure of the Medium

1952 • 195 citations

Purification and structural properties of gelsolin, a Ca2+-activated regulatory protein of macrophages.

1980 • 189 citations

Structure of macrophage actin-binding protein molecules in solution and interacting with actin filaments

1981 • 188 citations

Fimbrin is a cytoskeletal protein that crosslinks F-actin in vitro.

1981 • 187 citations

F-actin-binding and cross-linking properties of porcine brain fodrin, a spectrin-related molecule.

1982 • 176 citations

Cytoskeleton of human platelets at rest and after spreading.

1980 • 176 citations

Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells.

1980 • 176 citations

The effects of cytochalasins on actin polymerization and actin ATPase provide insights into the mechanism of polymerization.

1980 • 175 citations

Distribution of actin-binding protein and myosin in macrophages during spreading and phagocytosis.

1980 • 175 citations

Isolation and characterization of actin and actin-binding protein from human platelets.

1981 • 174 citations

Reorganization of actin in platelets stimulated by thrombin as measured by the DNase I inhibition assay.

1979 • 169 citations

Spectrin-actin interaction. Phosphorylated and dephosphorylated spectrin tetramer cross-link F-actin.

1979 • 168 citations

F actin assembly modulated by villin: Ca++-dependent nucleation and capping of the barbed end

1981 • 167 citations

Filamin, a new high-molecular-weight protein found in smooth muscle and nonmuscle cells. Purification and properties of chicken gizzard filamin

1977 • 165 citations

Spectrin-actin associations studied by electron microscopy of shadowed preparations

1980 • 162 citations

Interactions between actin, myosin, and an actin-binding protein from rabbit alveolar macrophages. Alveolar macrophage myosin Mg-2+-adenosine triphosphatase requires a cofactor for activation by actin.

1975 • 162 citations

A chemical comparison of tropomyosins from muscle and non-muscle tissues

1975 • 160 citations

Cytochalasin B, Its Interaction with Actin and Actomyosin from Muscle

1972 • 159 citations

Actin-gelsolin interactions. Evidence for two actin-binding sites.

1984 • 156 citations

Actin-binding protein promotes the bipolar and perpendicular branching of actin filaments.

1980 • 156 citations

The gelation of actin by actin-binding protein.

1978 • 155 citations

Distribution of actin-binding protein and myosin in polymorphonuclear leukocytes during locomotion and phagocytosis

1981 • 153 citations

Electron Microscopic Particle Length of F-Actin Polymerized in Vitro

1970 • 152 citations

Regulation of actin polymerization by villin, a 95,000 dalton cytoskeletal component of intestinal brush borders

1980 • 149 citations

Myosin phosphorylation in intact platelets.

1981 • 148 citations

Acrosomal reaction of Thyone sperm. II. The kinetics and possible mechanism of acrosomal process elongation.

1982 • 143 citations

Purification and properties of filamin, and actin binding protein from chicken gizzard.

1976 • 141 citations

Interaction of filamin with f-actin in solution.

1977 • 133 citations

Myosin-linked regulatory systems

1981 • 132 citations

A calcium- and pH-regulated protein from Dictyostelium discoideum that cross-links actin filaments.

1982 • 130 citations

International cell biology 1980–1981

1982 • 128 citations

Isolation of calcium-dependent platelet proteins that interact with actin

1981 • 128 citations

High-affinity interaction of vinculin with actin filaments in vitro

1982 • 125 citations

Uni-Directional Growth of F-Actin

1976 • 124 citations

Actin polymerization induced by chemotactic peptide and concanavalin A in rat neutrophils.

1982 • 122 citations

F-Actin-Depolymerizing Activity of Human Serum

1979 • 120 citations

Three-dimensional structure of actin filaments and of an actin gel made with actin-binding protein.

1983 • 120 citations

Human platelets contain profilin, a potential regulator of actin polymerisability

1978 • 118 citations

The polymerization of actin. III. Aggregates of nonfilamentous actin and its associated proteins: a storage form of actin.

1976 • 117 citations

The polymerization of actin: II. how nonfilamentous actin becomes nonrandomly distributed in sperm: evidence for the association of this actin with membranes

1976 • 110 citations

Release of intracellular membrane-bound calcium precedes the onset of stimulus-induced exocytosis in platelets

1980 • 109 citations

Isolation and some properties of macrophage .alpha.-actinin: evidence that it is not an actin gelling protein

1984 • 109 citations

Human Platelet Myosin

1971 • 106 citations

Expression of the beta subunit of spectrin in nonerythroid cells.

1983 • 105 citations

Isolation and some structural and functional properties of macrophage tropomyosin

1983 • 103 citations

Calcium control of microfilaments: uncoupling of the F-actin-severing and -bundling activity of villin by limited proteolysis in vitro.

1981 • 102 citations

Platelet actin: Sub‐cellular distribution and association with profilin

1978 • 101 citations

Characterization of platelet extracts before and after stimulation with respect to the possible role of profilactin as microfilament precursor

1981 • 100 citations

Effects of Cytochalasin B on Actin Filaments

1973 • 99 citations

Ca2+-sensitive gelation of actin filaments by a new protein factor

1979 • 98 citations

Partial reconstruction of the microvillus core bundle: characterization of villin as a Ca(++)-dependent, actin-bundling/depolymerizing protein

1982 • 96 citations

Nucleated polymerization of actin from the membrane-associated ends of microvillar filaments in the intestinal brush border.

1982 • 96 citations

Isolation and characterization of a calcium-sensitive alpha-actinin-like protein from human platelet cytoskeletons.

1981 • 95 citations

Role of fimbrin and villin in determining the interfilament distances of actin bundles

1983 • 94 citations

Purification and properties of human platelet P235. A high molecular weight protein substrate of endogenous calcium-activated protease(s).

1982 • 93 citations

β-Actinin, a Regulatory Protein of Muscle

1977 • 93 citations

Characterization of brevin, a serum protein that shortens actin filaments

1981 • 92 citations

An actin-destabilizing factor is present in human plasma

1979 • 91 citations

Structural comparison of several actin-binding macromolecules.

1980 • 87 citations

The interaction of equine platelet tropomyosin with skeletal muscle actin.

1981 • 87 citations

Purification of mammalian filamin. Similarity to high molecular weight actin-binding protein in macrophages, platelets, fibroblasts, and other tissues.

1978 • 85 citations

Human platelets contain gelsolin. A regulator of actin filament length.

1982 • 83 citations

Interactions of actin, myosin, and an actin-binding protein of chronic myelogenous leukemia leukocytes.

1976 • 81 citations

Actin-binding protein amplifies actomyosin contraction, and gelsolin confers calcium control on the direction of contraction

1980 • 81 citations

Treadmilling of actin at physiological salt concentrations

1982 • 81 citations

Polymerization of actin. V. A new organelle, the actomere, that initates the assembly of actin filaments in Thyone sperm

1978 • 80 citations

Direct electron microscopic visualization of barbed end capping and filament cutting by intestinal microvillar 95-kdalton protein (villin): a new actin assembly assay using the limulus acrosomal process

1983 • 79 citations

Changes in surface-bound and exchangeable calcium during platelet activation.

1982 • 77 citations

Cooperative binding of tropomyosin to muscle and Acanthamoeba actin.

1979 • 76 citations

Phosphorylation of platelet actin-binding protein during platelet activation

1982 • 73 citations

Three-dimensional organization of microfilaments and microtubules in the cytoskeleton

1979 • 73 citations

Reconstitution and regulation of actin gel-sol transformation with purified filamin and villin.

1981 • 73 citations

The role of myosin light chains in regulating actin-myosin interaction

1981 • 67 citations

Microheterogeneity of avian and mammalian vinculin

1982 • 67 citations

Abundance, relative gelation activity, and distribution of the 95,000-dalton actin-binding protein from Dictyostelium discoideum.

1983 • 67 citations

Isolation and Characterization of Profilactin and Profilin from Calf Thymus and Brain

1980 • 65 citations

Polymerization of actin. VI. The polarity of the actin filaments in the acrosomal process and how it might be determined.

1979 • 64 citations

Some perspectives on the viscosity of actin filaments.

1982 • 63 citations

Purification of a calcium-sensitive actin gelation protein from Acanthamoeba.

1981 • 62 citations

Novel form of non-muscle tropomyosin in human fibroblasts

1983 • 61 citations

An actin depolymerizing protein from pig plasma

1981 • 60 citations

Non‐polymerizability of platelet tropomyosin and its NH₂‐ and COOH‐terminal sequences

1978 • 60 citations

Electron microscopic studies of platelet secretion.

1974 • 58 citations

Structural aspects of vinculin-actin interactions

1982 • 56 citations

Isolation of an inhibitor of actin polymerization from human polymorphonuclear leukocytes.

1981 • 53 citations

Microfilaments and tropomyosin of cultured mammalian cells: isolation and characterization

1980 • 53 citations

An actin-binding protein in human platelets. Interactions with alpha-actinin on gelatin of actin and the influence of cytochalasin B.

1978 • 53 citations

Structure of crystalline actin sheets

1980 • 52 citations

Acumentin, a protein in macrophages which caps the ‘pointed’ end of actin filaments

1982 • 52 citations

Polymerization of Actin

1966 • 50 citations

Cytochalasin B and the structure of actin gels II. Further evidence for the splitting of F-actin by cytochalasin B

1980 • 46 citations

Tropomyosin Inhibits the Interaction of F-Actin and Filamin1

1978 • 44 citations

Myosin phosphorylation, cell motility and smooth muscle contraction

1978 • 42 citations

The State of Actin in Activated Human Platelets

1981 • 42 citations

Effect of cytochalasin B on formation and properties of muscle F-actin

1976 • 41 citations

A platelet inhibitor protein with cytochalasin-like activity against actin polymerization in vitro

1980 • 40 citations

Human platelet P235: A high M_r protein which restricts the length of actin filaments

1982 • 40 citations

Actin Gelation and the Structure of Cortical Cytoplasm

1982 • 39 citations

Porcine platelet tropomyosin

1981 • 38 citations

Nucleation of actin polymerization from profilactin Opposite effects of different nuclei

1982 • 38 citations

Phosphorylation of filamin and other proteins in cultured fibroblasts

1977 • 38 citations

Isolation of a high molecular weight actin-binding protein from baby hamster kidney (BHK-21) cells.

1979 • 37 citations

Reversible compression of cytoplasm

1982 • 37 citations

Reactivation of contraction in detergent-lysed teleost retinal cones.

1982 • 36 citations

The contractile system of blood platelets and its function.

1979 • 35 citations

Platelet tropomyosin: lack of binding to skeletal muscle troponin and correlation with sequence

1978 • 34 citations

alpha-Actinin Promotes Polymerization of Actin from Profilactin

1980 • 32 citations

A Study of β-Actinin, Myofibrillar Protein from Rabbin Skeletal Muscle

1971 • 31 citations

A New Regulatory Protein that Affects the State of Actin Polymerization1

1981 • 29 citations

The Role of Myosin Phosphorylation in Regulating Actin-Myosin Interaction in Human Blood Platelets

1978 • 26 citations

Platelet Contractile Proteins

1986 • 26 citations

Acumentin, an actin-modulating protein of rabbit pulmonary macrophages

1982 • 22 citations

Isolation of actin-binding protein and villin from toad oocytes

1983 • 21 citations

The effects of platelet tropomyosin on the ATPase activities of muscle actomyosin subfragment 1 in the absence and presence of troponin, its components, and calmodulin.

1981 • 20 citations

Characterization and localization of actinogelin, a Ca2+ - sensitive actin accessory protein, in nonmuscle cells.

1982 • 19 citations

Effect of actin-binding protein on the sedimentation properties of actin.

1982 • 19 citations

Ca2+-induced lysis of platelet secretory granules.

1982 • 19 citations

Platelet Contractile Proteins

1977 • 16 citations

The Polymerization of Actin

1981 • 16 citations

Purification and characterization of an inhibitor protein with cytochalasin-like acitvity from bovine adrenal medulla

1981 • 15 citations

The microfilament network of the platelet.

1982 • 14 citations

Purification and Characterization of Actinogelin, a Calcium-Sensitive Actin-Accessory Protein, from Rat Liver

1982 • 13 citations

Tropomyosin-like Protein in Chick Embryo Fibroblasts1

1975 • 12 citations

Filamin, a high relative molecular mass actin‐binding protein from smooth muscles, promotes actin polymerization

1981 • 11 citations

Purification of calcium-sensitive regulatory protein of platelets which inhibits the gelation of actin

1982 • 11 citations

Distribution of actin, myosin, actin-binding protein and gelsolin in cultured lymphoid cells

1982 • 10 citations

Effect of α-actinin on actin structure viscosity studies

1981 • 9 citations

[30] Purification and properties of avian and mammalian filamins

1982 • 7 citations

Rheological Studies on Calcium-Sensitive Gelation of Actin Filaments by Actinogelin1

1981 • 7 citations

Cell β-Actinin, an Accelerator of Actin Polymerization, Isolated from Rat Kidney Cytosol<xref ref-type="fn" rid="fn1"><sup>1</sup></xref>

1981 • 5 citations

A review of: “Transport phenomena in fluids edited by Howard J. Hanley. Marcel Dekker, New York and London (1969).”

1971 • 1 citations

Deleted Work

1955 • 0 citations