Hormonally mediated negative regulation of human pro-opiomelanocortin gene expression after transfection into mouse L cells.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Sedimentation characteristics of rapidly labelled RNA from HeLa cells

1962 • 1,033 citations

Characterization of DNA sequences through which cadmium and glucocorticoid hormones induce human metallothionein-IIA gene

1984 • 955 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Nuclear localization of unoccupied oestrogen receptors

1984 • 882 citations

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

1981 • 776 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 • 646 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Regulation of Simian Virus 40 Transcription: Sensitive Analysis of the RNA Species Present Early in Infections by Virus or Viral DNA

1979 • 623 citations

The glucocorticoid receptor binds to defined nucleotide sequences near the promoter of mouse mammary tumour virus

1983 • 619 citations

Regulation of α genes of herpes simplex virus: Expression of chimeric genes produced by fusion of thymidine kinase with α gene promoters

1981 • 449 citations

The transfer and stable integration of the HSV thymidine kinase gene into mouse cells

1978 • 382 citations

A small segment of polyoma virus DNA enhances the expression of a cloned β-globin gene over a distance of 1400 base pairs

1981 • 339 citations

Characterization of a common precursor to corticotropin and beta-lipotropin: identification of beta-lipotropin peptides and their arrangement relative to corticotropin in the precursor synthesized in a cell-free system.

1977 • 331 citations

Deletion mapping of DNA regions required for SV40 early region promoter function in vivo.

1982 • 328 citations

The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements

1983 • 299 citations

Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus

1982 • 276 citations

The mouse metallothionein-I gene is transcriptionally regulated by cadmium following transfection into human or mouse cells

1982 • 265 citations

Subfragments of the large terminal repeat cause glucocorticoid-responsive expression of mouse mammary tumor virus and of an adjacent gene.

1983 • 238 citations

Regulated expression of human growth hormone genes in mouse cells

1982 • 219 citations

Integration, transcription, and control of a Drosophila heat shock gene in mouse cells.

1981 • 212 citations

Activation of a heterologous promoter in response to dexamethasone and cadmium by metallothionein gene 5′-flanking DNA

1984 • 195 citations

High-sensitivity S1 mapping with single-stranded [32PIDNA probes synthesized from bacteriophage M13mp templates

1984 • 188 citations

Differences in human α-, β- and δ-globin gene expression in monkey kidney cells

1982 • 172 citations

Characterization of the structural gene and putative 5′-regulatory sequences for human proopiomelanocortin

1982 • 164 citations

Hormonal inducibility of rat α2u globulin genes in transfected mouse cells

1981 • 131 citations

Factors governing the expression of a bacterial gene in mammalian cells.

1981 • 126 citations

Glucocorticoid effect on the level of corticotropin messenger RNA activity in rat pituitary.

1977 • 108 citations

Expression of simian virus 40-rat preproinsulin recombinants in monkey kidney cells: use of preproinsulin RNA processing signals.

1981 • 94 citations

A large product of cell-free translation of messenger RNA coding for corticotropin.

1976 • 84 citations

Effects of Steroid Hormones on the Level of Corticotropin Messenger RNA Activity in Cultured Mouse‐Pituitary‐Tumor Cells

1978 • 78 citations

Regulated expression of human interferon beta 1 gene after transduction into cultured mouse and rabbit cells.

1982 • 76 citations

Steroid Receptors and the Mechanism of the Specificity of Glucocorticoid Responsiveness of Somatic Cell Hybrids between Hepatoma Tissue Culture Cells and Mouse Fibroblasts

1974 • 63 citations

Factors Governing the Expression of a Bacterial Gene in Mammalian Cells

1981 • 45 citations

Transcription in vivo from SV40 early promoter deletion mutants without repression by large T antigen.

1983 • 44 citations

Ectopic Hormone Production Viewed as an Abnormality in Regulation of Gene Expression

1980 • 33 citations

DNA sequences required for transcription in vivo of the human corticotropin-beta-lipotropin precursor gene.

1982 • 31 citations

Nuclear Localization of Unoccupied Oestrogen Receptors

1984 • 14 citations