Gene transfer to human cells using retrovirus vectors produced by a new polytropic packaging cell line

Viral RNA-dependent DNA Polymerase: RNA-dependent DNA Polymerase in Virions of RNA Tumour Viruses

1970 • 1,992 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

Developmental potential and dynamic behavior of hematopoietic stem cells

1986 • 888 citations

Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.

1987 • 881 citations

A new class of murine leukemia virus associated with development of spontaneous lymphomas.

1977 • 718 citations

Introduction of a selectable gene into primitive stem cells capable of long-term reconstitution of the hemopoietic system of W/W mice

1985 • 663 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse

1984 • 527 citations

[40] Use of retroviral vectors for gene transfer and expression

1993 • 412 citations

High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range.

1984 • 407 citations

Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells.

1995 • 357 citations

Naturally occurring murine leukemia viruses in wild mice: characterization of a new "amphotropic" class

1976 • 351 citations

Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene.

1985 • 342 citations

A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina.

1992 • 261 citations

Receptor interference groups of 20 retroviruses plating on human cells

1990 • 249 citations

Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells

1983 • 214 citations

Retroviruses as probes for mammalian development: Allocation of cells to the somatic and germ cell lineages

1986 • 213 citations

Amphotropic host range of naturally occuring wild mouse leukemia viruses

1976 • 210 citations

A novel murine oncornavirus with dual eco- and xenotropic properties.

1975 • 201 citations

Clonal fluctuation within the haematopoietic system of mice reconstituted with retrovirus-infected stem cells.

1987 • 168 citations

Interference grouping of murine leukemia viruses: A distinct receptor for the MCF-Recombinant viruses in mouse cells

1982 • 151 citations

Generation of Helper-Free Amphotropic Retroviruses That Transduce a Dominant-Acting, Methotrexate-Resistant Dihydrofolate Reductase Gene

1985 • 125 citations

Analysis of the env gene of a molecularly cloned and biologically active Moloney mink cell focus-forming proviral DNA

1982 • 125 citations

Different recombinant murine leukemia viruses use different cell surface receptors

1984 • 105 citations

Tunicamycin treatment of CHO cells abrogates multiple blocks to retrovirus infection, one of which is due to a secreted inhibitor

1992 • 102 citations

At least four viral genes contribute to the leukemogenicity of murine retrovirus MCF 247 in AKR mice

1985 • 102 citations

Different murine cell lines manifest unique patterns of interference to superinfection by murine leukemia viruses

1985 • 86 citations

Retroviral Vector-Mediated Gene Transfer into Human Hematopoietic Progenitor Cells

1985 • 83 citations

Retroviruses and the study of cell lineage

1987 • 78 citations

Properties of a unique form of the murine amphotropic leukemia virus receptor expressed on hamster cells

1994 • 69 citations

Genetic mapping of a mouse chromosomal locus required for mink cell focus-forming virus replication

1983 • 65 citations

Host range of mink cell focus-inducing viruses

1985 • 59 citations

The human cytomegalovirus UL37 immediate-early regulatory protein is an integral membrane N-glycoprotein which traffics through the endoplasmic reticulum and Golgi apparatus

1996 • 48 citations

Construction of recombinants between molecular clones of murine retrovirus MCF 247 and Akv: determinant of an in vitro host range property that maps in the long terminal repeat

1985 • 44 citations

Use of Retroviral Vectors for Gene Transfer and Expression

1995 • 33 citations

Localization of the amphotropic murine leukemia virus receptor gene to the pericentromeric region of human chromosome 8

1991 • 27 citations

Expression of a selectable gene transferred by a retroviral vector to hematopoietic stem cells and stromal cells in murine continuous bone marrow cultures.

1987 • 25 citations

Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses.

1990 • 23 citations