Expression of VLA-alpha 2, VLA-alpha 6, and VLA-beta 1 chains in normal mucosa and adenomas of the colon, and in colon carcinomas and their liver metastases.

New Perspectives in Cell Adhesion: RGD and Integrins

1987 • 4,835 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

FIBRONECTIN AND ITS RECEPTORS

1988 • 1,336 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Laminin and Other Basement Membrane Components

1987 • 900 citations

The Spread of Rectal Cancer and its Effect on Prognosis

1958 • 807 citations

Identification of multiple cell adhesion receptors for collagen and fibronectin in human fibrosarcoma cells possessing unique alpha and common beta subunits.

1987 • 727 citations

BIOCHEMICAL INTERACTIONS OF TUMOR CELLS WITH THE BASEMENT MEMBRANE

1986 • 693 citations

Laminin receptor on platelets is the integrin VLA-6

1988 • 679 citations

Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor α4β1

1990 • 616 citations

The VLA protein family. Characterization of five distinct cell surface heterodimers each with a common 130,000 molecular weight beta subunit.

1987 • 512 citations

The function of multiple extracellular matrix receptors in mediating cell adhesion to extracellular matrix: preparation of monoclonal antibodies to the fibronectin receptor that specifically inhibit cell adhesion to fibronectin and react with platelet glycoproteins Ic-IIa.

1988 • 446 citations

The membrane glycoprotein Ia-IIa (VLA-2) complex mediates the Mg++-dependent adhesion of platelets to collagen.

1989 • 422 citations

The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others.

1989 • 388 citations

The alpha 1/beta 1 and alpha 6/beta 1 integrin heterodimers mediate cell attachment to distinct sites on laminin.

1990 • 375 citations

Endothelial cells use alpha 2 beta 1 integrin as a laminin receptor.

1989 • 363 citations

A novel vitronectin receptor integrin (αvβx) is responsible for distinct adhesive properties of carcinoma cells

1989 • 352 citations

Adhesive protein receptors on hematopoietic cells

1988 • 350 citations

Characterization of the cell surface heterodimer VLA-4 and related peptides.

1987 • 340 citations

A complex of platelet glycoproteins Ic and IIa identified by a rat monoclonal antibody.

1987 • 334 citations

A novel integrin (alpha E beta 4) from human epithelial cells suggests a fourth family of integrin adhesion receptors.

1989 • 314 citations

Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins

1989 • 305 citations

Association of the VLA a Subunit with a Novel Protein

1989 • 285 citations

Peyer's patch-specific lymphocyte homing receptors consist of a VLA-4-like alpha chain associated with either of two integrin beta chains, one of which is novel.

1989 • 270 citations

Renewal of the epithelium in the descending colon of the mouse. I. Presence of three cell populations: Vacuolated‐columnar, mucous and argentaffin

1971 • 252 citations

Affinity chromatographic isolation of the melanoma adhesion receptor for the IIICS region of fibronectin and its identification as the integrin alpha 4 beta 1.

1990 • 244 citations

Gastrointestinal Epithelial Renewal

1977 • 243 citations

Fibronectin receptor structures in the VLA family of heterodimers

1987 • 230 citations

Interactions of a neuronal cell line (PC12) with laminin, collagen IV, and fibronectin: identification of integrin-related glycoproteins involved in attachment and process outgrowth.

1987 • 216 citations

Alterations in integrin receptor expression on chemically transformed human cells: specific enhancement of laminin and collagen receptor complexes.

1990 • 213 citations

Molecular cloning of the rat integrin alpha 1-subunit: a receptor for laminin and collagen.

1990 • 191 citations

Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures.

1988 • 186 citations

Widespread histologic distribution of the alpha 2 beta 1 integrin cell-surface collagen receptor.

1990 • 183 citations

Very late activation antigens on rheumatoid synovial fluid T lymphocytes. Association with stages of T cell activation.

1986 • 174 citations

Purification and characterization of mammalian integrins expressed by a rat neuronal cell line (PC12): evidence that they function as alpha/beta heterodimeric receptors for laminin and type IV collagen.

1988 • 167 citations

A novel integrin beta subunit is associated with the vitronectin receptor alpha subunit (alpha v) in a human osteosarcoma cell line and is a substrate for protein kinase C.

1989 • 167 citations

Integrin VLA-3: ultrastructural localization at cell-cell contact sites of human cell cultures.

1989 • 163 citations

Use of the monoclonal antibody 12F1 to characterize the differentiation antigen VLA-2.

1987 • 154 citations

Isolation and characterization of a platelet surface collagen binding complex related to VLA-2

1988 • 152 citations

VLA‐1: a T cell surface antigen which defines a novel late stage of human T cell activation

1985 • 151 citations

Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets.

1988 • 137 citations

Human B lymphocytes define an alternative mechanism of adhesion to fibronectin. The interaction of the alpha 4 beta 1 integrin with the LHGPEILDVPST sequence of the type III connecting segment is sufficient to promote cell attachment.

1990 • 132 citations

Platelet glycoproteins Ia, Ic, and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types.

1988 • 127 citations

Identification of Integrin-like Matrix Receptors with Affinity for Interstitial Collagens

1989 • 123 citations

Human melanoma cells express a novel integrin receptor for laminin

1989 • 120 citations

Expression of the VLA family of integrins in human intestine

1990 • 80 citations

The Fine Structure of Human Rectal Mucosa

1968 • 74 citations

Cell Replication in the Gastrointestinal Tract of Man

1965 • 73 citations

The Human Cell Surface Glycoprotein Complex (gp 120,200) Recognized by Monoclonal Antibody K20 is a Component Binding to Phytohaemagglutinin on T Cells

1986 • 64 citations

Mechanism of fibronectin-mediated cell migration: Dependence or independence of cell migration susceptibility on RGDS-directed receptor (integrin)

1989 • 61 citations

Reduced cell adhesion to fibronectin and laminin is associated with altered glycosylation of β₁, integrins in a weakly metastatic glycosylation mutant

1989 • 48 citations

Thein vitro invasiveness and interactions with laminin of K-1735 melanoma cells. Evidence for different laminin-binding affinities in high and low metastatic variants

1989 • 37 citations

The Laminin Receptor and Basement Membrane Dissolution: Role in Tumour Metastasis

1984 • 32 citations

Leukocyte adhesion molecules involved in inflammation.

1989 • 19 citations

Anti‐(Arg‐Gly‐Asp‐Ser) antibody and its interaction with fibronectin, fibrinogen and platelets

1988 • 15 citations

K20 and ICO-10 monoclonal antibodies (gp120/200; Thy-1): immunophenotyping of human solid tumours

1990 • 2 citations