Structure and Function of the Macrophage Mannose Receptor

Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products.

1995 • 2,531 citations

STRUCTURAL BASIS OF LECTIN-CARBOHYDRATE RECOGNITION

1996 • 1,074 citations

The C‐type lectin superfamily in the immune system

1998 • 1,022 citations

The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

1995 • 959 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

Structure of a C-type mannose-binding protein complexed with an oligosaccharide

1992 • 873 citations

Biology of Animal Lectins

1993 • 752 citations

Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

1985 • 659 citations

Macrophage phagocytosis of virulent but not attenuated strains of Mycobacterium tuberculosis is mediated by mannose receptors in addition to complement receptors.

1993 • 603 citations

Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in Cos-1 cells.

1990 • 501 citations

Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor

1991 • 444 citations

The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells

1997 • 397 citations

Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

1994 • 397 citations

Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains.

1990 • 370 citations

The Mannose Receptor Delivers Lipoglycan Antigens to Endosomes for Presentation to T Cells by CD1b Molecules

1997 • 339 citations

Mannose receptor‐mediated uptake of antigens strongly enhances HLA class II‐restricted antigen presentation by cultured dendritic cells

1997 • 324 citations

Contribution to ligand binding by multiple carbohydrate-recognition domains in the macrophage mannose receptor.

1992 • 320 citations

Cloning and expression of a membrane receptor for secretory phospholipases A2.

1994 • 278 citations

Circulating C-terminal propeptide of type I procollagen is cleared mainly via the mannose receptor in liver endothelial cells

1990 • 236 citations

Structural requirements for high affinity binding of complex ligands by the macrophage mannose receptor.

1993 • 231 citations

The Human 180-kDa Receptor for Secretory Phospholipases A2

1995 • 224 citations

Cloning and sequence analysis of the cation-independent mannose 6-phosphate receptor.

1988 • 210 citations

Plasma clearance of glycoproteins with terminal mannose and N-acetylglucosamine by liver non-parenchymal cells. Studies with β-glucuronidase, N-acetyl-β-<scp>d</scp>-glucosaminidase, ribonuclease B and agalacto-orosomucoid

1978 • 204 citations

Ca2+-dependent carbohydrate-recognition domains in animal proteins

1993 • 200 citations

Characterization of human blood coagulation factor XII cDNA. Prediction of the primary structure of factor XII and the tertiary structure of beta-factor XIIa.

1985 • 194 citations

Molecular cloning of pancreatic group I phospholipase A2 receptor.

1994 • 183 citations

A cysteine-rich domain of the “mannose” receptor mediates GalNAc-4-SO ₄ binding

1998 • 170 citations

Structural Analysis of Monosaccharide Recognition by Rat Liver Mannose-binding Protein

1996 • 165 citations

Clearance of Neutrophil-derived Myeloperoxidase by the Macrophage Mannose Receptor

1990 • 134 citations

Binding of sugar ligands to Ca(2+)-dependent animal lectins. I. Analysis of mannose binding by site-directed mutagenesis and NMR.

1994 • 133 citations

Characterization of the mannose/fucose receptor on human mononuclear phagocytes.

1982 • 125 citations

Mechanism of Ca2- and Monosaccharide Binding to a C-type Carbohydrate-recognition Domain of the Macrophage Mannose Receptor

1997 • 97 citations

Characterization of a Novel Member of the Macrophage Mannose Receptor Type C Lectin Family

1996 • 94 citations

Binding of tissue-type plasminogen activator by the mannose receptor

1991 • 94 citations

Phagocytic chimeric receptors require both transmembrane and cytoplasmic domains from the mannose receptor.

1992 • 92 citations

Increasing diversity of animal lectin structures

1995 • 86 citations

Isolation and characterization of a mannose-specific endocytosis receptor from human placenta.

1987 • 85 citations

The macrophage/endothelial cell mannose receptor cDNA encodes a protein that binds oligosaccharides terminating with SO₄-4-GalNAcβ1,4GlcNAcβ or Man at independent sites

1997 • 77 citations

Receptor-mediated pinocytosis of mannose/N-acetylglucosamine-terminated glycoproteins and lysosomal enzymes by macrophages

1980 • 76 citations

Identification of the Binding Domain for Secretory Phospholipases A2 on Their M-type 180-kDa Membrane Receptor

1995 • 76 citations

Evidence for the involvement of type II domains in collagen binding by 72 kDa type IV procollagenase

1991 • 72 citations

Characterization of ligand binding to a carbohydrate-recognition domain of the macrophage mannose receptor.

1994 • 72 citations

Isolation and characterization of a mannose receptor from human pigment epithelium.

1991 • 69 citations

Uptake and transport of mannosylated ligands by alveolar macrophages. Studies on ATP-dependent receptor-ligand dissociation.

1985 • 65 citations

The isolation of a rat alveolar macrophage lectin.

1986 • 63 citations

Lysine-based Cluster Mannosides That Inhibit Ligand Binding to the Human Mannose Receptor at Nanomolar Concentration

1996 • 62 citations

Biosynthesis and processing of the mannose receptor in human macrophages

1989 • 54 citations

Clearance of lysosomal hydrolases following intravenous infusion

1976 • 54 citations

Clearance of lysosomal hydrolases following intravenous infusion

1976 • 51 citations

Human epidermal Langerhans cells express the mannose-fucose binding receptor

1998 • 49 citations

Role of mannose/N-acetylglucosamine receptors in blood clearance and cellular attachment of Leishmania donovani

1988 • 45 citations

Antagonists of the Mannose Receptor and the LDL Receptor–Related Protein Dramatically Delay the Clearance of Tissue Plasminogen Activator

1997 • 44 citations

Isolation and Characterization of the Mannose Receptor From Human Liver Potentially Involved in the Plasma Clearance of Tissue–Type Plasminogen Activator

1992 • 38 citations

Orientation of sugars bound to the principal C-type carbohydrate-recognition domain of the macrophage mannose receptor

1998 • 34 citations

Letters to the Glyco-Forum

1997 • 34 citations