Phagocytic chimeric receptors require both transmembrane and cytoplasmic domains from the mannose receptor.

Fc Receptors

1991 • 1,220 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.

1987 • 802 citations

Studies on the mechanism of phagocytosis. I. Requirements for circumferential attachment of particle-bound ligands to specific receptors on the macrophage plasma membrane.

1975 • 595 citations

Molecular characterization of the human macrophage mannose receptor: demonstration of multiple carbohydrate recognition-like domains and phagocytosis of yeasts in Cos-1 cells.

1990 • 501 citations

Toxoplasma gondii : Fusion Competence of Parasitophorous Vacuoles in Fc Receptor-Transfected Fibroblasts

1990 • 446 citations

Uptake of Pneumocystis carinii mediated by the macrophage mannose receptor

1991 • 444 citations

Primary structure of the mannose receptor contains multiple motifs resembling carbohydrate-recognition domains.

1990 • 370 citations

Sequences within and adjacent to the transmembrane segment of alpha-2,6-sialyltransferase specify Golgi retention.

1991 • 296 citations

A macrophage Fcγ receptor and the mast cell receptor for IgE share an identical subunit

1989 • 268 citations

Isolation and Expression of Functional High-Affinity Fc Receptor Complementary DNAs

1989 • 257 citations

The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation

1991 • 246 citations

Initial events during phagocytosis by macrophages viewed from outside and inside the cell: membrane-particle interactions and clathrin.

1982 • 217 citations

The essential tyrosine of the internalization signal in lysosomal acid phosphatase is part of a β turn

1991 • 165 citations

Mutations of immunoglobulin transmembrane and cytoplasmic domains: Effects on intracellular signaling and antigen presentation

1990 • 154 citations

Human Fc gamma RII, in the absence of other Fc gamma receptors, mediates a phagocytic signal.

1991 • 140 citations

Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.

1990 • 121 citations

The structure and function of vertebrate mannose lectin-like proteins

1988 • 105 citations

Leishmania promastigotes require opsonic complement to bind to the human leukocyte integrin Mac-1 (CD11b/CD18).

1992 • 104 citations

Ligand-induced stimulation of epidermal growth factor receptor mutants with altered transmembrane regions.

1988 • 81 citations

Structural analysis of the transmembrane domain of the epidermal growth factor receptor.

1991 • 80 citations

Evidence supporting a passive role for the insulin receptor transmembrane domain in insulin-dependent signal transduction

1991 • 59 citations

Transmembrane domain of the envelope gene of a polycythemia-inducing retrovirus determines erythropoietin-independent growth.

1989 • 59 citations

Correlation of the structure of the transmembrane domain of the neu oncogene-encoded p185 protein with its function.

1990 • 56 citations

Fc receptor-mediated binding and endocytosis by human mononuclear phagocytes: monomeric IgG is not endocytosed by U937 cells and monocytes.

1985 • 53 citations

Mutagenesis of the human transferrin receptor: two cytoplasmic phenylalanines are required for efficient internalization and a second-site mutation is capable of reverting an internalization-defective phenotype.

1991 • 48 citations