P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

1987 • 2,788 citations

Pharmacology of drugs that alter multidrug resistance in cancer.

1990 • 970 citations

The multidrug transporter, a double-edged sword.

1988 • 763 citations

Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone.

1992 • 677 citations

Mechanisms mediating renal secretion of organic anions and cations

1993 • 484 citations

Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).

1992 • 335 citations

Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney.

1993 • 94 citations

P‐glycoprotein‐mediated transcellular transport of MDR‐reversing agents

1993 • 92 citations

The pathophysiology of sandimmune (cyclosporine) in man and animals

1990 • 87 citations

Transepithelial transport of vinblastine by kidney-derived cell lines. Application of a new kinetic model to estimate in situ Km of the pump

1990 • 77 citations

Effect of cyclosporine on colchicine secretion by the kidney multidrug transporter studied in vivo.

1992 • 63 citations

Identification of P-glycoprotein in renal brush border membranes

1989 • 50 citations

Postnatal development of organic cation transport and mdr gene expression in mouse kidney.

1992 • 39 citations

Energy-dependent transport of digoxin across renal tubular cell monolayers (LLC-PK1)

1993 • 38 citations

Fluorescein transport in isolated proximal tubules in vitro: epifluorometric analysis

1990 • 32 citations

Aquatic models for the study of renal transport function and pollutant toxicity.

1987 • 27 citations

Identification of the multidrug resistance-related P-glycoprotein as a cyclosporin binding protein

1989 • 26 citations

Photoaffinity labeling of the organic cation/H+ exchanger in renal brush border membrane vesicles.

1992 • 18 citations

Interaction of rat kidney P-glycoprotein with a urinary component and various drugs including cyclosporin A

1994 • 15 citations

Cyclosporine: conformation and analogues as tools for studying its mechanism of action.

1988 • 14 citations