HIV-1 Tat Inhibits Human Natural Killer Cell Function by Blocking L-Type Calcium Channels

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Adhesion receptors of the immune system

1990 • 6,585 citations

Biology of Natural Killer Cells

1989 • 2,970 citations

Cellular uptake of the tat protein from human immunodeficiency virus

1988 • 2,690 citations

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 • 983 citations

STRUCTURE AND FUNCTION OF VOLTAGE-GATED ION CHANNELS

1995 • 941 citations

Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients

1990 • 899 citations

Modulation of ion-channel function by G-protein-coupled receptors

1994 • 764 citations

Molecular Mechanisms of Lymphocyte-Mediated Cytotoxicity and Their Role in Immunological Protection and Pathogenesis In Vivo

1996 • 614 citations

Induction of Apoptosis in Uninfected Lymphocytes by HIV-1 Tat Protein

1995 • 581 citations

Models of T cell anergy: is there a common molecular mechanism?

1996 • 575 citations

The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

1996 • 365 citations

Inhibition of Antigen-Induced Lymphocyte Proliferation by Tat Protein from HIV-1

1989 • 338 citations

Signal Transduction during Natural Killer Cell Activation: Inside the Mind of a Killer

1997 • 293 citations

Inhibitory MHC class I receptors on NK cells and T cells

1996 • 288 citations

The expression of the interleukin 6 gene is induced by the human immunodeficiency virus 1 TAT protein.

1994 • 250 citations

Cytotoxicity with target DNA breakdown by rat basophilic leukemia cells expressing both cytolysin and granzyme A

1992 • 243 citations

[42] Assay for calcium channels

1985 • 191 citations

Human immunodeficiency virus type 1 Tat upregulates interleukin-2 secretion in activated T cells

1994 • 184 citations

Defective natural immunity: an early manifestation of human immunodeficiency virus infection.

1995 • 166 citations

Heterogeneous distribution and transmembrane signaling properties of lymphocyte function-associated antigen (LFA-1) in human lymphocyte subsets.

1989 • 158 citations

Mechanism of defective NK cell activity in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. I. Defective trigger on NK cells for NKCF production by target cells, and partial restoration by IL 2.

1986 • 158 citations

HIV-tat protein is a heparin-binding angiogenic growth factor.

1996 • 152 citations

Anti-Ig-induced Calcium Influx in Rat B Lymphocytes Mediated by cGMP through a Dihydropyridine-sensitive Channel

1996 • 118 citations

CD31/PECAM‐1‐driven chemokine‐independent transmigration of human T lymphocytes

1996 • 90 citations

Pathogenesis of the natural killer cell deficiency in AIDS

1990 • 81 citations

Involvement of Dihydropyridine-sensitive Calcium Channels in Human Dendritic Cell Function

1998 • 77 citations

p40, a novel surface molecule involved in the regulation of the non‐major histocompatibility complex‐restricted cytolytic activity in humans

1995 • 73 citations

The natural killer cell

1992 • 66 citations

The role of Ca2+ in activation of mature cytotoxic T lymphocytes for lysis.

1987 • 49 citations

The RGD-containing domain of exogenous HIV-1 Tat inhibits the engulfment of apoptotic bodies by dendritic cells

1997 • 42 citations

CD45‐mediated regulation of LFA1 function in human natural killer cells. Anti‐CD45 monoclonal antibodies inhibit the calcium mobilization induced via LFA1 molecules

1993 • 37 citations

Complex Molecular Mechanism for Dihydropyridine Binding to L-Type Ca2+-Channels As Revealed by Fluorescence Resonance Energy Transfer

1994 • 31 citations

Dissection of lymphocyte function‐associated antigen 1‐dependent adhesion and signal transduction in human natural killer cells shown by the use of cholera or pertussis toxin

1996 • 23 citations

Partial Purification and Identification of an Immunosuppressive Factor in AIDS Sera

1993 • 10 citations

The Association of HIV-1 Tat with Nuclei Is Regulated by Ca2+ Ions and Cytosolic Factors

1997 • 10 citations