Secondary V(D)J recombination in B-1 cells

Receptor editing in self-reactive bone marrow B cells.

1993 • 1,026 citations

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

1989 • 1,015 citations

Receptor editing: an approach by autoreactive B cells to escape tolerance.

1993 • 920 citations

The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.

1983 • 810 citations

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

1996 • 657 citations

Ly-1 B cells: functionally distinct lymphocytes that secrete IgM autoantibodies.

1984 • 652 citations

Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

1994 • 637 citations

Progenitors for Ly-1 B cells are distinct from progenitors for other B cells.

1985 • 599 citations

Induction of self-tolerance in mature peripheral B lymphocytes

1989 • 525 citations

Functional immunoglobulin transgenes guide ordered B-cell differentiation in Rag-1-deficient mice.

1994 • 426 citations

Antigen-induced B-cell death and elimination during germinal-centre immune responses

1995 • 377 citations

Soluble antigen can cause enhanced apoptosis of germinal-centre B cells

1995 • 301 citations

Receptor Editing in a Transgenic Mouse Model: Site, Efficiency, and Role in B Cell Tolerance and Antibody Diversification

1997 • 291 citations

V(D)J Recombinase Activity in a Subset of Germinal Center B Lymphocytes

1997 • 284 citations

Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice

1992 • 281 citations

Neoteny in Lymphocytes: Rag1 and Rag2 Expression in Germinal Center B Cells

1996 • 272 citations

V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

1997 • 247 citations

B Cell Development under the Condition of Allelic Inclusion

1997 • 240 citations

Analysis of the B-cell progenitor compartment at the level of single cells

1994 • 232 citations

Reexpression of RAG-1 and RAG-2 Genes in Activated Mature Mouse B cells

1996 • 219 citations

Development of B-1 cells: segregation of phosphatidyl choline-specific B cells to the B-1 population occurs after immunoglobulin gene expression.

1994 • 181 citations

Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse.

1994 • 167 citations

A Prematurely Expressed Igκ Transgene, but Not a VκJκ Gene Segment Targeted into the Igκ Locus, Can Rescue B Cell Development in λ5-Deficient Mice

1996 • 142 citations

Permanent alteration of the murine Ly‐1 B repertoire due to selective depletion of Ly‐1 B cells in neonatal animals

1989 • 116 citations

Targeted insertion of a variable region gene into the immunoglobulin heavy chain locus

1993 • 112 citations

Effects of Breeding Environments on Generation and Activation of Autoreactive B-1 Cells in Anti-red Blood Cell Autoantibody Transgenic Mice

1997 • 90 citations

VH gene replacement in hyperselected B cells of the quasimonoclonal mouse.

1997 • 77 citations

Antigen-receptor cross-linking induces peritoneal B-cell apoptosis in normal but not autoimmunity-prone mice

1994 • 62 citations

Rearrangement and expression of endogenous immunoglobulin genes occur in many murine B cells expressing transgenic membrane IgM.

1988 • 55 citations

Bar Mitzvah for B-1 Cells: How Will They Grow Up?

1997 • 37 citations