The Drosophila Netrin receptor Frazzled guides axons by controlling Netrin distribution

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1993 • 9,476 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Netrin-1 Is Required for Commissural Axon Guidance in the Developing Vertebrate Nervous System

1996 • 1,253 citations

Slit Proteins Bind Robo Receptors and Have an Evolutionarily Conserved Role in Repulsive Axon Guidance

1999 • 1,155 citations

Drosophila: a laboratory manual

1990 • 1,081 citations

Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor

1996 • 982 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

Phenotype of mice lacking functional Deleted in colorectal cancer (Dec) gene

1997 • 764 citations

RETRACTED: A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion

1999 • 686 citations

Cytonemes

1999 • 602 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

Monoclonal antibodies against the Drosophila nervous system.

1982 • 534 citations

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

1997 • 511 citations

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

1992 • 503 citations

UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues

1996 • 491 citations

Genetic Analysis of Netrin Genes in Drosophila: Netrins Guide CNS Commissural Axons and Peripheral Motor Axons

1996 • 459 citations

frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance

1996 • 456 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein

1997 • 372 citations

Neuroglia and Pioneer Neurons Express UNC-6 to Provide Global and Local Netrin Cues for Guiding Migrations in C. elegans

1996 • 359 citations

Drosophila: A laboratory manual

1990 • 350 citations

Guidance Cues at the Drosophila CNS Midline: Identification and Characterization of Two Drosophila Netrin/UNC-6 Homologs

1996 • 322 citations

Turning of Retinal Growth Cones in a Netrin-1 Gradient Mediated by the Netrin Receptor DCC

1997 • 280 citations

Genetic Analysis of the Mechanisms Controlling Target Selection: Complementary and Combinatorial Functions of Netrins, Semaphorins, and IgCAMs

1998 • 256 citations

Expression of the UNC-5 guidance receptor in the touch neurons of C. elegans steers their axons dorsally

1993 • 237 citations

Chimeric Axon Guidance Receptors

1999 • 190 citations

Embryonic development of axon pathways in the Drosophila CNS. II. Behavior of pioneer growth cones

1989 • 153 citations

Targeted neuronal ablation: the role of pioneer neurons in guidance and fasciculation in the CNS of Drosophila

1997 • 129 citations

Embryonic phenotype of Unc5h3 mutant mice suggests chemorepulsion during the formation of the rostral cerebellar boundary

1998 • 124 citations

The Netrin receptor Frazzled is required in the target for establishment of retinal projections in the Drosophila visual system

1999 • 28 citations