Cell-mediated immunity and its role in resistance to infection.
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Abstract
References (127)
CELLULAR RESISTANCE TO INFECTION
1962 • 1,422 citations
Glucocorticosteroid Therapy: Mechanisms of Action and Clinical Considerations
1976 • 1,035 citations
THE INFLUENCE OF IMMUNOLOGICALLY COMMITTED LYMPHOID CELLS ON MACROPHAGE ACTIVITY IN VIVO
1969 • 932 citations
Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytes choriomeningitis
1974 • 832 citations
Immunodepression after major surgery in normal patients.
1975 • 424 citations
Immunocompetence of Patients with Protein-Calorie Malnutrition
1973 • 393 citations
The Compromised Host and Infection. II. Deep Fungal Infection
1969 • 375 citations
H-2 compatibility is required for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus.
1975 • 366 citations
DEPRESSED CELL-MEDIATED IMMUNITY IN PATIENTS WITH PRIMARY INTRACRANIAL TUMORS
1972 • 365 citations
REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS
1972 • 352 citations
Toxoplasmosis in the Compromised Host
1976 • 339 citations
POTENTIATION OF T-CELL-MEDIATED IMMUNITY BY SELECTIVE SUPPRESSION OF ANTIBODY FORMATION WITH CYCLOPHOSPHAMIDE
1974 • 328 citations
Specific IgE antibodies in immune adherence of normal macrophages to Schistosoma mansoni schistosomules
1975 • 304 citations
Immunologic Dysfunction in Heroin Addicts
1974 • 301 citations
T‐Cell‐Mediated Immunopathology in Viral Infections
1974 • 287 citations
Drug-Induced Restoration of Cutaneous Delayed Hypersensitivity in Anergic Patients with Cancer
1973 • 264 citations
INHIBITION OF RESPIRATORY VIRUS INFECTION BY LOCALLY APPLIED INTERFERON
1973 • 261 citations
Suppressor thymus-derived lymphocytes in fungal infection.
1976 • 261 citations
FŒTAL THYMIC TRANSPLANT IN A CASE OF DiGEORGE'S SYNDROME
1968 • 250 citations
Effects of Corticosteroids on Human Monocyte Function
1974 • 245 citations
Delayed hypersensitivity in Hodgkin's disease
1972 • 244 citations
GLUCOCORTICOID SUPPRESSION OF MACROPHAGE MIGRATION INHIBITORY FACTOR
1973 • 235 citations
STUDIES ON MEDIATOR PRODUCTION BY HIGHLY PURIFIED HUMAN T AND B LYMPHOCYTES
1974 • 234 citations
Hodgkin's disease. An immunodepleting and immunosuppressive disorder.
1975 • 215 citations
T Cell Response to Viral and Bacterial Infection
1974 • 197 citations
Intensity of immunosuppressive therapy and the incidence of pneumocystis carinii pneumonitis
1975 • 196 citations
Defective cellular immunity in renal failure: depression of reactivity of lymphocytes to phytohemagglutinin by renal failure serum
1971 • 192 citations
IMPLANTATION OF A FŒTAL THYMUS, RESTORING IMMUNOLOGICAL COMPETENCE IN A PATIENT WITH THYMIC APLASIA (DiGEORGE'S SYNDROME)
1968 • 188 citations
The Wiskott-Aldrich Syndrome
1972 • 180 citations
MECHANISMS OF RECOVERY FROM A GENERALIZED VIRAL INFECTION: MOUSEPOX
1970 • 180 citations
Defective Regulation of Inflammatory Mediators in Hodgkin's Disease
1974 • 180 citations
Listeriosis Complicating Malignant Disease
1967 • 179 citations
MECHANISMS OF RECOVERY FROM A GENERALIZED VIRAL INFECTION: MOUSEPOX
1971 • 175 citations
Adverse Effect of Cytosine Arabinoside on Disseminated Zoster in a Controlled Trial
1973 • 173 citations
Adoptive Immunity to Intracellular Infection
1967 • 171 citations
Molecular basis of interferon action: Inhibition of viral RNA translation
1966 • 171 citations
Fetal Malnutrition and Postnatal Immunocompetence
1975 • 169 citations
Phytohemagglutinin Transformation and Circulating Lymphocyte Subpopulations in Insulin-dependent Diabetic Patients
1974 • 164 citations
Regulation of the Prevalence and Intensity of Schistosomiasis in Man: Immunology or Ecology?
1973 • 160 citations
EFFECT OF NORMAL AND ACTIVATED HUMAN MACROPHAGES ON TOXOPLASMA GONDII
1974 • 156 citations
A Role for Activated Macrophages in Resistance to Infection with Toxoplasma
1972 • 148 citations
THE INFLUENCE OF CORTISONE ON EXPERIMENTAL FUNGUS INFECTIONS IN MICE*
1960 • 147 citations
Immunosuppression and toxoplasmic encephalitis
1975 • 147 citations
Measles infection of human mononuclear cells. I. Acute infection of peripheral blood lymphocytes and monocytes.
1975 • 134 citations
Immune mechanisms by which the spread of viral infections is stopped
1974 • 124 citations
Administration of Human Leukocyte Interferon in Herpes Zoster. I. Safety, Circulating Antiviral Activity, and Host Responses to Infection
1974 • 124 citations
Studies on the Mechanisms of Resistance to Phylogenetically Diverse Intracellular Organisms
1969 • 123 citations
Salmonellosis in patients with neoplastic disease. A review of 100 episodes at Memorial Cancer Center over a 13-year period
1971 • 120 citations
Lymphocyte response to phytohemagglutinin in Hodgkin's disease
1970 • 119 citations
FEEDBACK INHIBITION OF SPECIFICALLY SENSITIZED LYMPHOCYTES
1974 • 118 citations
Impaired delayed-hypersensitivity responses in 154 patients with untreated Hodgkin's disease.
1973 • 117 citations
MECHANISMS OF RECOVERY FROM A GENERALIZED VIRAL INFECTION: MOUSEPOX
1971 • 116 citations
Co-Operation Between Antibodies and Cells in Immunity to a Nematode Parasite
1974 • 114 citations
Effect of measles vaccine on immunologic responsiveness.
1969 • 113 citations
The Prevalence of Tuberculosis and Positive Tuberculin Skin Tests in a Steroid-Treated Asthmatic Population
1976 • 110 citations
Interferon, antibody, and other host factors in herpes zoster
1972 • 108 citations
Subversion of host defense mechanisms by murine tumors. I. A circulating factor that suppresses macrophage-mediated resistance to infection.
1976 • 106 citations
Cryptococcosis
1950 • 103 citations
Immunological destruction of herpes simplex virus I infected cells
1974 • 102 citations
Induced and spontaneous diabetes mellitus and suppression of cell-mediated immunologic responses. Granuloma formation, delayed dermal reactivity and allograft rejection.
1976 • 97 citations
DEPRESSED MONOCYTE CHEMOTAXIS DURING ACUTE INFLUENZA INFECTION
1975 • 94 citations
Mouth Lesions in Iron-Deficient Anemia: Relationship to Candida albicans in Saliva and to Impairment of Lymphocyte Transformation
1975 • 91 citations
Schistosoma mansoni infection in mice depleted of thymus-dependent lymphocytes. II. Pathology and altered pathogenesis.
1973 • 89 citations
Effect of Leukocyte Interferon on Urinary Excretion of Cytomegalovirus by Infants
1976 • 88 citations
The Use of Killed Vaccines in Immunization against an Intracellular Parasite: Toxoplasma Gondii
1972 • 85 citations
Anesthesia and the Immune Response
1971 • 83 citations
Influenza: Response of T-Cell Lymphopenia to Thymosin
1976 • 82 citations
Use of Thymosin in the Treatment of Primary Immunodeficiency Diseases and Cancer
1976 • 82 citations
MACROPHAGE-DIGESTED ANTIGEN AS INDUCER OF DELAYED HYPERSENSITIVITY
1971 • 80 citations
Host Defenses against Viral Disease
1974 • 75 citations
Cyclophosphamide suppression of established cell-mediated immunity. Quantitative vs. qualitative changes in lymphocyte populations.
1975 • 68 citations
The Decline of Cell-mediated Immunity in Aging Mice
1974 • 63 citations
LEVAMISOLE IN PREVENTION OF RECURRENT UPPER-RESPIRATORY-TRACT INFECTIONS IN CHILDREN
1976 • 62 citations
Levamisole for Recurrent Herpes Labialis
1974 • 60 citations
Augmentation of human monocyte chemotactic response by levamisole
1976 • 58 citations
Schistosoma mansoni infection in mice depleted of thymus-dependent lymphocytes. I. Eosinophilia and immunologic responses to a schistosomal egg preparation.
1973 • 57 citations
The Role of Thymus-Derived Lymphocytes in the in Vitro Activation of Macrophages to Kill Listeria Monocytogenes
1973 • 56 citations
Delayed Hypersensitivity Skin Testing. II. Clinical Correlates and Anergy
1974 • 55 citations
Immune Response to Mycobacterium tuberculosis in Rats
1973 • 54 citations
Antieosinophil serum and the kinetics of eosinophilia in Schistosomiasis mansoni.
1975 • 54 citations
Effect of Human Exogenous Leukocyte Interferon in Cytomegalovirus Infections
1976 • 53 citations
Suppression of Delayed Hypersensitivity in Schistosome-Infected Patients by Niridazole
1975 • 50 citations
Human Leukocyte Interferon for the Prevention of Recurrences of Herpetic Keratitis
1976 • 43 citations
SUPPRESSION OF CELL-MEDIATED IMMUNITY TO INFECTION BY AN ANTIMITOTIC DRUG
1970 • 42 citations
Depression of tuberculin reaction in mild and moderate protein-calorie malnourished children following BCG vaccination.
1975 • 41 citations
Conditions for Immunosuppression by Rifampicin
1973 • 37 citations
Cellular imunity in neoplasia: Antigen and mitogen responses in patients with bronchiogenic carcinoma
1975 • 37 citations
Interferon in Treatment of Dendritic Keratitis in Humans: A Preliminary Report
1976 • 37 citations
Clinico-pathological study of thymic dysplasia.
1968 • 36 citations
Effect of Cobalt-60 Irradiation upon Cell-Mediated Immunity
1973 • 33 citations
Studies on the mechanism of suppression of delayed hypersensitivity by the antischistosomal compund niridazole.
1975 • 33 citations
Measles Epidemics in Greenland
1962 • 32 citations
Age-related changes in the cellular immune response of lymph node and thymus cells in long-lived mice
1975 • 32 citations
Murine Malaria: The Role of Humoral Factors and Macrophages in Destruction of Parasitized Erythrocytes
1971 • 31 citations
Effects of cytotoxic and immunosuppressive agents on the immune system
1975 • 30 citations
Immunological Responsiveness of Tuberculosis Patients Receiving Rifampin
1974 • 30 citations
Deficiency of lymphocyte antigen recognition in Hodgkin's disease.
1973 • 29 citations
Cell-Mediated and Humoral Immunity to Protozoan Infections
1974 • 29 citations
The effect of hydrocortisone on lymphocyte-mediated cytolysis
1973 • 29 citations
Mechanism of selective nonspecific cell-mediated cytotoxicity of virus-infected cells
1976 • 28 citations
In vitro evidence of normal lymphocyte function in some patients with Hodgkin's disease and negative delayed cutaneous hypersensitivity.
1973 • 28 citations
Immune Deficiency: Evaluation, Diagnosis, and Therapy
1974 • 27 citations
Technical Aspects of the Rosette Technique for Detecting Human Circulating B and T Lymphocytes Normal Values and Some Remarks on Null Lymphocytes
1974 • 26 citations
Leukocyte migration inhibitory factor (LMIF) induced by concanavalin A: standardized microassay for production in vitro.
1975 • 23 citations
Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions.
1975 • 22 citations
LEVAMISOLE AND FUNCTIONS OF PERITONEAL MACROPHAGES
1975 • 19 citations
Immunologic evaluation of patients with cancer by delayed hypersensitivity reactions.
1975 • 17 citations
Effects of cytotoxic immunosuppressants on tuberculin-sensitive lymphocytes in guinea pigs.
1975 • 17 citations
NATURE AND BIOLOGICAL ACTIVITIES OF THYMUS HORMONES: PROSPECTS FOR THE FUTURE
1975 • 17 citations
Enhancement of Host Defense Mechanisms by Pharmacological Agents
1975 • 16 citations
Effect of a Topical Interferon Inducer on Rhinovirus Infections in Volunteers
1976 • 15 citations
Susceptibility to Infection with Pasteurella tularensis and the Immune Response of Mice Exposed to Continuous Low Dose Rate Radiation
1969 • 15 citations
Cleavage of bacterial flagellin with proteolytic enzymes
1972 • 14 citations
Schistosoma mansoni: Immunity in Macaca mulatta
1971 • 14 citations
In vitro observations on sarcoid lymphocytes and their correlation with cutaneous energy and clinical severity of disease.
1973 • 14 citations
Thymosin Therapy Creates a “Hassall”(?)
1975 • 13 citations
Immunotherapy with transfer factor in disseminated coccidioidal osteomyelitis and arthritis.
1974 • 12 citations
EFFECT OF IRRADIATION ON ESTABLISHED DELAYED HYPERSENSITIVITY
1973 • 11 citations
Immune Response in Aged and Young Subjects, following Administration of Large Doses of Tuberculin
1975 • 9 citations
Cell-Mediated Immunity in the Uremic Rat
1975 • 8 citations
Effects of rubeola on tuberculosis
1953 • 8 citations
Superinfection in Lymphoreticular Diseases
1971 • 8 citations
Lymphocyte transformation and production of a human mononuclear leucocyte chemotactic factor in patients with Hodgkin's disease.
1974 • 6 citations
Hodgkin's disease complicated by tuberculosis. A twenty-year experience.
1966 • 6 citations
Suppression of in vitro lymphocyte responsiveness to purified protein derivative by measles virus
1975 • 6 citations
Effects of Continuous Irradiation of Mice on the Immune Response to Live Listeria monocytogenes
1967 • 3 citations
Effect of x-irradiation on induction of delayed hypersensitivity as measured by in vitro macrophage migration inhibition.
1972 • 2 citations