Water-macromolecule interactions by NMR: a quadrature-free constant-time approach and its application to CI2.

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient

1965 • 7,940 citations

NMR of Proteins and Nucleic Acids

2006 • 5,989 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

1H, 13C and 15N chemical shift referencing in biomolecular NMR

1995 • 2,294 citations

Rapid recording of 2D NMR spectra without phase cycling. Application to the study of hydrogen exchange in proteins

1989 • 1,395 citations

Investigation of complex networks of spin-spin coupling by two-dimensional NMR

1981 • 1,223 citations

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

1993 • 891 citations

[12] Chemical shifts as a tool for structure determination

1994 • 865 citations

Protein Hydration in Aqueous Solution

1991 • 778 citations

Resolution enhancement and spectral editing of uniformly 13C-enriched proteins by homonuclear broadband 13C decoupling

1992 • 400 citations

NMR in biological research: Peptides and proteins

1976 • 384 citations

Truncated driven nuclear overhauser effect (TOE). A new technique for studies of selective 1H1H overhauser effects in the presence of spin diffusion

1979 • 355 citations

Crystal structure of hen egg-white lysozyme at a hydrostatic pressure of 1000 atmospheres

1987 • 330 citations

Structural comparison of two serine proteinase-protein inhibitor complexes: Eglin-C-subtilisin Carlsberg and CI-2-subtilisin Novo

1988 • 307 citations

Studies of protein hydration in aqueous solution by direct NMR observation of individual protein-bound water molecules

1989 • 306 citations

Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds

1987 • 260 citations

Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2

1993 • 256 citations

Sequential proton NMR assignments and secondary structure of hen egg white lysozyme in solution

1988 • 233 citations

Use of a water flip-back pulse in the homonuclear NOESY experiment

1995 • 164 citations

Analysis of the ¹H‐NMR spectra of ferrichrome peptides. I. The non‐amide protons

1978 • 154 citations

Application of Phase-Modulated CLEAN Chemical EXchange Spectroscopy (CLEANEX-PM) to Detect Water−Protein Proton Exchange and Intermolecular NOEs

1997 • 150 citations

A practical approach to three-dimensional NMR spectroscopy

1987 • 146 citations

Measurement of amide proton exchange rates and NOEs with water in 13C/15N-enriched calcineurin B

1993 • 144 citations

Untitled

1998 • 134 citations

Homonuclear broadband-decoupled absorption spectra, with linewidths which are independent of the transverse relaxation rate

1979 • 131 citations

Measurement of fast proton exchange rates in isotopically labeled compounds

1993 • 127 citations

[13] Use of chemical shifts and coupling constants in nuclear magnetic resonance structural studies on peptides and proteins

1994 • 124 citations

Two-dimensional NMR spectroscopy with soft pulses

1987 • 119 citations

NMR identification of hydrophobic cavities with ow water occupancies in protein structures using small gas molecules

1997 • 94 citations

Water Exchange Filter with Improved Sensitivity (WEX II) to Study Solvent-Exchangeable Protons. Application to the Consensus Zinc Finger Peptide CP-1

1996 • 88 citations

Application of ω1-decoupled 2D correlation spectra to the study of proteins

1984 • 79 citations

Improvement of NMR experiments by employing semiselective half-Gaussian-shaped pulses

1989 • 72 citations

Separation of intramolecular NOE and exchange peaks in water exchange spectroscopy using spin-echo filters

1996 • 70 citations

Refinement of the three-dimensional solution structure of barley serine proteinase inhibitor 2 and comparison with the structures in crystals

1991 • 69 citations

Determination of the residence time of water molecules hydrating B ′ -DNA and B -DNA, by one-dimensional zero-enhancement nuclear overhauser effect spectroscopy 1 1Edited by I. Tinoco

1999 • 68 citations

New NMR methods for the characterization of bound waters in macromolecules

1993 • 61 citations

Water Exchange Filter (WEX Filter) for Nuclear Magnetic Resonance Studies of Macromolecules

1994 • 58 citations

Localization of bound water in the solution structure of a complex of the erythroid transcription factor GATA-1 with DNA

1994 • 49 citations

Solvent exposure of specific nuclei of angiotensin II determined by NMR solvent saturation method

1974 • 47 citations

Homonuclear 1D and 2D NMR Experiments for the Observation of Solvent–Solute Interactions

1996 • 44 citations

Main-chain conformational features at different conformations of the side-chains in proteins

1998 • 43 citations

Investigation of the solution structure of chymotrypsin inhibitor 2 using molecular dynamics: comparison to X-ray crystallographic and NMR data

1995 • 41 citations

Solution conformations of proline rings in proteins studied by NMR spectroscopy

1995 • 39 citations

Optimization of constant-time evolution in multidimensional NMR experiments

1992 • 39 citations

Multidimensional NMR in Liquids

1997 • 38 citations

Selective excitation of intense solvent signals in the presence of radiation damping

1995 • 36 citations

New pulsed field gradient NMR experiments for the detection of bound water in proteins

1995 • 33 citations

Side-chains in native and random coil protein conformations. Analysis of NMR coupling constants and χ 1 torsion angle preferences 1 1Edited by P. E. Wright

1998 • 33 citations

Reassessment of the structure of chymotrypsin inhibitor 2 (CI-2) using time-averaged NMR restraints

1994 • 33 citations

ROESY with Water Flip Back for High-Field NMR of Biomolecules

1997 • 31 citations

Suppression of radiation damping during selective excitation of the water signal: The WANTED sequence

1996 • 30 citations

Sequence specific assignment of the proton nuclear magnetic resonance spectrum of barley serine proteinase inhibitor 2

1987 • 26 citations

Diffusion Filters for Separation of Solvent−Protein and Protein−Protein Nuclear Overhauser Effects (HYDRA)

1996 • 26 citations

Editing of Chemical Exchange-Relayed NOEs in NMR Experiments for the Observation of Protein–Water Interactions

1999 • 17 citations

15N-edited Three-Dimensional NOESY-HMQC with Water Flipback: Enhancement of Weak Labile1H Resonances of Protein Side Chains Contacting DNA

1998 • 15 citations

A study of protein-water exchange through the off-resonance ROESY experiment: Application to the DNA-binding domain of AlcR

1996 • 14 citations

A two-dimensional nuclear overhauser enhancement experiment using semiselective soft pulses, and its applications to proteins

1988 • 13 citations

Water-protein NOEs: Optimized scheme for selective water excitation.

1999 • 13 citations

Gradient-purged isotope filter experiments for the detection of bound water in proteins

1999 • 11 citations

Signal Enhancement Using 45° Water Flipback for 3D 15N-Edited ROESY and NOESY HMQC and HSQC

1999 • 9 citations

Band-selective editing of exchange-relay in protein-water NOE experiments.

1999 • 8 citations