Functional NMDA Receptors Are Transiently Active and Support the Survival of Purkinje Cells in Culture

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Molecular Diversity of Glutamate Receptors and Implications for Brain Function

1992 • 2,535 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

The cerebellum and neural control

1984 • 2,322 citations

NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

1986 • 1,842 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

The physiology of excitatory amino acids in the vertebrate central nervous system

1987 • 1,718 citations

Physiological and pathophysiological roles of excitatory amino acids during central nervous system development

1990 • 1,427 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Modulation of Neuronal Migration by NMDA Receptors

1993 • 1,034 citations

NMDA-receptor-dependent synaptic plasticity: multiple forms and mechanisms

1993 • 893 citations

The TINS/TiPS Lecture the molecular biology of mammalian glutamate receptor channels

1993 • 882 citations

Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody

1994 • 860 citations

The role of divalent cations in the N‐methyl‐D‐aspartate responses of mouse central neurones in culture.

1988 • 810 citations

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1992 • 805 citations

Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

1990 • 649 citations

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1994 • 496 citations

Synaptic‐ and agonist‐induced excitatory currents of Purkinje cells in rat cerebellar slices.

1991 • 475 citations

Differential expression of five N‐methyl‐D‐aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats

1994 • 463 citations

N-methyl-d-aspartate promotes the survival of cerebellar granule cells in culture

1988 • 437 citations

Tonic Activation of NMDA Receptors by Ambient Glutamate Enhances Excitability of Neurons

1989 • 434 citations

The molecular basis of NMDA receptor subtypes: native receptor diversity is predicted by subunit composition

1994 • 373 citations

Involvement of the N -Methyl D-Aspartate (NMDA) Receptor in Synapse Elimination During Cerebellar Development

1992 • 308 citations

Excitatory synaptic currents in Purkinje cells

1990 • 267 citations

Cell-cell interactions influence survival and differentiation of purified purkinje cells in vitro

1994 • 252 citations

Electrical activity in cerebellar cultures determines Purkinje cell dendritic growth patterns

1991 • 239 citations

Serotonin suppressesN-methyl-d-aspartate responses in acutely isolated spinal dorsal horn neurons of the rat

1990 • 222 citations

STUDIES OF THE INTER‐RELATIONSHIP BETWEEN CEREBROSPINAL FLUID AND PLASMA AMINO ACID CONCENTRATIONS IN NORMAL INDIVIDUALS

1977 • 216 citations

Transient biochemical compartmentalization of Purkinje cells during early cerebellar development

1985 • 213 citations

NMDA receptor regulation of neuronal morphology in cultured hippocampal neurons

1989 • 204 citations

Ontogeny of the calcium binding protein calbindin D-28k in the rat nervous system

1987 • 203 citations

CSF amino acids and plasma‐CSF amino acid ratios in adults¹

1975 • 195 citations

Interactions between entorhinal axons and target hippocampal neurons: A role for glutamate in the development of hippocampal circuitry

1988 • 183 citations

Distinct spatiotemporal expressions of five NMDA receptor channel subunit mRNAs in the cerebellum

1994 • 183 citations

Development and death of external granular layer cells in the weaver mouse cerebellum: a quantitative study

1989 • 164 citations

Glutaminase-like immunoreactivity in the lower brainstem and cerebellum of the adult rat

1989 • 146 citations

Selective loss of Purkinje and granule cell responsiveness to in rat cerebellum during development

1987 • 139 citations

Excitatory amino acid receptor-channels in Purkinje cells in thin cerebellar slices

1991 • 130 citations

Maturation of climbing fiber responses in the rat

1971 • 126 citations

Postnatal development of the chemosensitivity of rat cerebellar purkinje cells to excitatory amino acids. An in vitro study

1987 • 125 citations

Apparent desensitization of NMDA responses in xenopus oocytes involves calcium-dependent chloride current

1990 • 124 citations

Cultivation of mouse cerebellar cells in serum free, hormonally defined media: Survival of neurons

1982 • 121 citations

Expression of NMDA channels on cerebellar Purkinje cells acutely dissociated from newborn rats

1992 • 120 citations

Pharmacological and immunocytochemical characterization of metabotropic glutamate receptors in cultured Purkinje cells

1992 • 116 citations

Glycine-insensitive desensitization of NMDA responses in cultured mouse embryonic neurons

1990 • 109 citations

Patch-clamp recording of amino acid-activated responses in "organotypic" slice cultures.

1988 • 101 citations

Optical monitoring of excitatory synaptic activity between cultured hippocampal neurons by a multi-site Ca2+ fluorometry

1987 • 99 citations

Calcium binding protein (calbindin-D28k) gene expression in the developing and aging mouse cerebellum

1990 • 95 citations

Responses to excitatory amino acids of Purkinje cells' and neurones of the deep nuclei in cerebellar slice cultures.

1990 • 93 citations

Purkinje cell survival is differentially regulated by metabotropic and ionotropic excitatory amino acid receptors

1993 • 90 citations

Transient Sensitivity of Rat Cerebellar Purkinje Cells to N‐methyl‐D‐aspartate during Development. A Voltage Clamp Study in in vitro Slices

1990 • 87 citations

Maintenance of immunocytologically identified Purkinje cells from mouse cerebellum in monolayer culture

1984 • 73 citations

Fura-2 measurements of cultured rat Purkinje neurons show dendritic localization of Ca2+ influx

1989 • 66 citations

Endogenous neurotransmitter activates N-methyl-D-aspartate receptors on differentiating neurons in embryonic cortex.

1990 • 64 citations

Rapid, sensitive, and simple method for quantification of both neurotoxic and neurotrophic effects of NMDA on cultured cerebellar granule cells

1990 • 51 citations

Transient direct connection of vestibular mossy fibers to the vestibulocerebellar Purkinje cells in early postnatal development of kittens

1989 • 41 citations

NMDA-receptors on Purkinje cell dendrites in guinea pig cerebellar slices

1987 • 39 citations

Cell Damage Associated with Changing the Medium of Mesencephalic Cultures in Serum‐Free Medium Is Mediated via N‐Methyl‐D‐Aspartate Receptors

1991 • 37 citations

Unique properties of non-N-methyl-D-aspartate excitatory responses in cultured purkinje neurons.

1989 • 31 citations

Cortical development: With an eye on neurotrophins

1996 • 23 citations

Differential effects of N-methyl-d-aspartic acid and l-homocysteic acid on cerebellar Purkinje neurons

1988 • 23 citations

MK-801 blocked the functional NMDA receptors in identified cerebellar neurons

1990 • 8 citations

and aspartate raise the cytosolic freee calcium concentration by acting upon receptors transiently expressed on immature cerebellar Purkinje cells

1991 • 5 citations