Microtubules are involved in the secretion of proteins at the apical cell surface of the polarized epithelial cell, Madin-Darby canine kidney

A low-viscosity epoxy resin embedding medium for electron microscopy

1969 • 12,996 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Pathways of Protein Secretion in Eukaryotes

1985 • 1,050 citations

Constitutive and Regulated Secretion of Proteins

1987 • 1,021 citations

Cell Surface Polarity in Epithelia

1985 • 880 citations

The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex.

1988 • 810 citations

A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide.

1986 • 510 citations

A membrane-cytoskeletal complex containing Na+,K+-ATPase, ankyrin, and fodrin in Madin-Darby canine kidney (MDCK) cells: implications for the biogenesis of epithelial cell polarity.

1989 • 319 citations

Microtubules and the organization of the Golgi complex

1985 • 311 citations

Colchicine inhibition of plasma protein release from rat hepatocytes.

1975 • 300 citations

Ankyrin links fodrin to the alpha subunit of Na,K-ATPase in Madin-Darby canine kidney cells and in intact renal tubule cells.

1989 • 276 citations

Inhibition of Collagen Secretion from Bone and Cultured Fibroblasts by Microtubular Disruptive Drugs

1972 • 266 citations

Vesicular stomatitis virus infects and matures only through the basolateral surface of the polarized epithelial cell line, MDCK

1984 • 236 citations

EFFECTS OF ANTIMICROTUBULAR AGENTS ON THE SECRETION OF COLLAGEN

1974 • 227 citations

Microtubule-acting drugs lead to the nonpolarized delivery of the influenza hemagglutinin to the cell surface of polarized Madin-Darby canine kidney cells.

1987 • 210 citations

The polarized distribution of an apical cell surface glycoprotein is maintained by interactions with the cytoskeleton of Madin-Darby canine kidney cells.

1988 • 209 citations

Constitutive apical secretion of an 80-kD sulfated glycoprotein complex in the polarized epithelial Madin-Darby canine kidney cell line.

1987 • 201 citations

Control of microtubule nucleation and stability in Madin-Darby canine kidney cells: the occurrence of noncentrosomal, stable detyrosinated microtubules.

1987 • 199 citations

Nocodazole, a microtubule-active drug, interferes with apical protein delivery in cultured intestinal epithelial cells (Caco-2).

1989 • 176 citations

Microtubules and actin filaments are not critically involved in the biogenesis of epithelial cell surface polarity.

1986 • 142 citations

Tryptic dissection and reconstitution of translocation activity for nascent presecretory proteins across microsomal membranes.

1979 • 124 citations

Exocytotic pathways exist to both the apical and the basolateral cell surface of the polarized epithelial cell MDCK

1985 • 121 citations

Synthesis of membrane glycoproteins in rat small-intestinal villus cells. Effect of colchicine on the redistribution of <scp>l</scp>-[1,5,6-3H]fucose-labelled membrane glycoproteins among Golgi, lateral basal and microvillus membranes

1979 • 93 citations

Human interleukin 1 beta is not secreted from hamster fibroblasts when expressed constitutively from a transfected cDNA.

1988 • 87 citations

Studies on intracellular transport of secretory proteins in the rat exocrine pancreas

1975 • 81 citations

Microtubules and the Intracellular Conversion of Proparathyroid Hormone to Parathyroid Hormone¹

1975 • 66 citations

Effect of colchicine on intestinal disaccharidases: correlation with biochemical aspects of cellular renewal

1970 • 64 citations

Role of microtubules in the synthesis, conversion, and release of (pro)insulin. A biochemical and radioautographic study in rat islets.

1979 • 58 citations

Chapter 20 Preservation of Biological Specimens for Observation in a Confocal Fluorescence Microscope and Operational Principles of Confocal Fluorescence Microscopy

1989 • 55 citations

Effect of colchicine on the transfer of IgA across hepatocytes into bile in isolated perfused rat livers

1980 • 50 citations

Biosynthesis of intestinal microvillar proteins. Role of the Golgi complex and microtubules

1983 • 50 citations

Role of fodrin in secretion

1987 • 45 citations

Influence of colchicine and vinblastine on the intracellular migration of secretory and membrane glycoproteins: III. Inhibition of intracellular migration of membrane glycoproteins in rat intestinal columnar cells and hepatocytes as visualized by light and electron‐microscope radioautography after ³h‐fucose injection

1984 • 45 citations

Energy-dependent intracellular translocation of proparathormone.

1977 • 41 citations

The influence of pH on the vesicular traffic to the surface of the polarized epithelial cell, MDCK.

1989 • 25 citations

Role of microtubules in the intracellular transport of growth hormone

1978 • 20 citations