Fibroblast growth factors modulate intestinal epithelial cell growth and migration

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Physiology of the Gastrointestinal Tract

2006 • 4,704 citations

Peptide Growth Factors and Their Receptors

1991 • 1,221 citations

Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture.

1989 • 914 citations

Purification and characterization of a newly identified growth factor specific for epithelial cells.

1989 • 842 citations

Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria.

1979 • 784 citations

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis.

1988 • 647 citations

Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues.

1986 • 531 citations

Immunodetection and quantitation of the two forms of transforming growth factor‐beta (TGF‐β1 and TGF‐β2) secreted by cells in culture

1989 • 453 citations

Cytokine modulation of intestinal epithelial cell restitution: Central role of transforming growth factor β

1993 • 446 citations

Fibroblast Growth Factors

1991 • 360 citations

Growth factor-induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model.

1991 • 355 citations

Regulation of intestinal epithelial cell growth by transforming growth factor type beta.

1989 • 341 citations

Fibroblast growth factor: Structural and biological properties

1987 • 334 citations

Effects of growth factors on an intestinal epithelial cell line: Transforming growth factor β inhibits proliferation and stimulates differentiation

1987 • 305 citations

Discovery of a New Mechanism and Development of Angiogenic Therapy That Accelerates Healing

1991 • 282 citations

Expression of basic fibroblast growth factor in normal human tissues.

1990 • 258 citations

Transforming growth factor β regulation of migration in wounded rat intestinal epithelial monolayers

1993 • 230 citations

Production of transforming growth factors by human colon cancer lines.

1986 • 227 citations

Intestinal epithelial restitution. Characterization of a cell culture model and mapping of cytoskeletal elements in migrating cells.

1992 • 224 citations

Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model.

1987 • 222 citations

Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells.

1989 • 219 citations

Measurement of in vivo proliferation in human colorectal mucosa using bromodeoxyuridine.

1992 • 218 citations

Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity.

1992 • 205 citations

Peptide Growth Factors and Their Receptors I

1990 • 187 citations

Rapid barrier restitution in an in vitro model of intestinal epithelial injury.

1989 • 168 citations

Epidermal Growth Factor Receptor of the Intestinal Enterocyte

1989 • 146 citations

Migration of IEC-6 cells: a model for mucosal healing

1992 • 144 citations

Epithelial Restitution in the Gastrointestinal Tract

1988 • 134 citations

Morphology and electrophysiology of guinea pig gastric mucosal repair in vitro

1983 • 133 citations

The roles of ethanol and of acid in the production of gastric mucosal erosions in rats

1981 • 132 citations

Repair of rabbit duodenal mucosa after acid injury in vivo and in vitro

1987 • 131 citations

Insulin-Like Growth Factors and the Developing and Mature Rat Small Intestine: Receptors and Biological Actions

1990 • 110 citations

Regulation of transforming growth factor expression in rat intestinal epithelial cell lines.

1991 • 109 citations

Gastric mucosal defense and repair

1987 • 101 citations

Secretion of insulin-like growth factor II (IGF-II) and IGF-binding protein-2 by intestinal epithelial (IEC-6) cells: implications for autocrine growth regulation.

1992 • 98 citations

Differentiation of rat small intestinal epithelial cells by extracellular matrix

1988 • 88 citations

Independent modulation of enterocyte migration and proliferation by growth factors, matrix proteins, and pharmacologic agents in an in vitro model of mucosal healing.

1992 • 84 citations

Basement membrane components are potent promoters of rat intestinal epithelial cell differentiation in vitro

1990 • 83 citations

Characterization of the inhibitory effects of transforming growth factor-beta on a human colon carcinoma cell line.

1987 • 77 citations

Restitution of frog gastric mucosa in vitro: Effect of basic fibroblast growth factor

1993 • 61 citations

Identification of basic fibroblast growth factor sensitivity and receptor and ligand expression in human colon tumor cell lines

1992 • 57 citations

Characterization of Type I and Type II Insulin-Like Growth Factor Receptors in an Intestinal Epithelial Cell Line*

1990 • 50 citations

Epithelial restitution in the large intestine of the rat following insult with bile salts

1988 • 31 citations

The major colonic cell mitogen extractable from colonic mucosa is an N terminally extended form of basic fibroblast growth factor

1991 • 29 citations