Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

1997 • 2,105 citations

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors α and δ

1997 • 2,100 citations

Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3)

1996 • 1,607 citations

Fatty Acids, Eicosanoids, and Hypolipidemic Agents Identified as Ligands of Peroxisome Proliferator-Activated Receptors by Coactivator-Dependent Receptor Ligand Assay

1997 • 1,158 citations

Dietary influences on serum lipids and lipoproteins.

1990 • 1,065 citations

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

1990 • 1,044 citations

Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young (MODY1)

1996 • 941 citations

Does fish oil lower blood pressure? A meta-analysis of controlled trials.

1993 • 688 citations

Fish Oil Prevents Insulin Resistance Induced by High-Fat Feeding in Rats

1987 • 658 citations

Mode of Action of Peroxisome Proliferators as Hypolipidemic Drugs.

1995 • 342 citations

Dietary Polyunsaturated Fatty Acid Regulation of Gene Transcription

1994 • 305 citations

Relationship between dietary fat and experimental mammary tumorigenesis: a review and critique.

1992 • 232 citations

The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex

1990 • 223 citations

Characterization of FadR, a global transcriptional regulator of fatty acid metabolism in Escherichia coli. Interaction with the fadB promoter is prevented by long chain fatty acyl coenzyme A.

1992 • 191 citations

Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids

1994 • 190 citations

Exclusive Homodimerization of the Orphan Receptor Hepatocyte Nuclear Factor 4 Defines a New Subclass of Nuclear Receptors

1995 • 187 citations

Dietary n‐3 (ω‐3) polyunsaturated fatty acid effects on animal tumorigenesis

1991 • 184 citations

Acyl‐CoA binding proteins: Multiplicity and function

1996 • 139 citations

Retinoid X receptor alpha forms tetramers in solution.

1995 • 94 citations

Liver Gene Expression

1994 • 91 citations

Recruitment of hepatocyte nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential.

1995 • 88 citations

TFIIB-Directed Transcriptional Activation by the Orphan Nuclear Receptor Hepatocyte Nuclear Factor 4

1996 • 67 citations

A Regulatory Element in the ApoCIII Promoter That Directs Hepatic Specific Transcription Binds to Proteins in Expressing and Nonexpressing Cell Types

1989 • 63 citations

Removal of hydrophobic compounds from biological fluids by a simple method

1980 • 61 citations

Marine oils and cardiovascular reactivity

1994 • 60 citations

Expression in Escherichia coli, purification and characterization of two mammalian thioesterases involved in fatty acid synthesis

1991 • 41 citations

Transcriptional activation by amphipathic carboxylic peroxisomal proliferators is induced by the free acid rather than the acyl‐CoA derivative

1994 • 40 citations

Fibrinogen and factor VII as risk factors in vascular disease.

1991 • 30 citations

An NF1 Motif Plays a Central Role in Hepatitis B Virus Enhancer

1994 • 26 citations