Nonionic Oligonucleotide Analogs as New Tools for Studies on the Structure and Function of Nucleic Acids Inside Living Cells

Are snRNPs involved in splicing?

1980 • 1,206 citations

[13] Bacterial Membranes

1971 • 653 citations

Outer membrane of gram-negative bacteria. XII. Molecular-sieving function of cell wall

1976 • 304 citations

Biochemical and biological effects of nonionic nucleic acid methylphosphonates

1981 • 224 citations

Nonionic nucleic acid analogs. Synthesis and characterization of dideoxyribonucleoside methylphosphonates

1979 • 186 citations

A study of the mechanism of DNA polymerase I from Escherichia coli with diastereomeric phosphorothioate analogs of deoxyadenosine triphosphate.

1979 • 172 citations

Size Restriction on Peptide Utilization in Escherichia coli

1968 • 155 citations

Nucleotide sequences of nuclear U1A RNAs from chicken, rat and man

1980 • 144 citations

Conformation and interaction of dinucleoside mono- and diphosphates. V. Syntheses and properties of adenine and thymine nucleoside alkyl phosphotriesters, the neutral analogs of dinucleoside monophosphates

1971 • 141 citations

Phosphorothioate analogs of nucleotides

1979 • 127 citations

Selective inhibition of Escherichia coli protein synthesis and growth by nonionic oligonucleotides complementary to the 3′ end of 16S rRNA

1981 • 108 citations

Alkyl phosphotriesters of dinucleotides and oligonucleotides. 4. Synthesis of oligodeoxyribonucleotide ethyl phosphotriesters and their specific complex formation with transfer ribonucleic acid

1974 • 84 citations

Oligothymidylate analogues having stereoregular, alternating methylphosphonate/phosphodiester backbones. Synthesis and physical studies.

1980 • 84 citations

Effects of a trinucleotide ethyl phosphotriester, G^mp(Et)G^mp(Et)U, on mammalian cells in culture

1977 • 77 citations

Selective inactivation of amino acid acceptor and ribosome-binding activities of Escherichia coli tRNA by modification with cyanogen bromide

1971 • 63 citations

Proton nuclear magnetic resonance studies on dideoxyribonucleoside methylphosphonates

1980 • 61 citations

Stereochemical course of DNA hydrolysis by nuclease S1.

1983 • 57 citations

Alkyl phosphotriesters of dinucleotides and oligonucleotides. 5. Inhibitory effect of complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation

1974 • 57 citations

Synthesis of isosteric phosphonate analogs of some biologically important phosphodiesters

1970 • 52 citations

Vinyl analogs of polynucleotides

1971 • 51 citations

[13] Stereochemistry of enzymic phosphoryl and nucleotidyl transfer

1982 • 49 citations

Duplex formation of a nonionic oligo(deoxythymidylate) analog [heptadeoxythymidylyl-(3'-5')-deoxythymidine heptaethyl ester (d-[Tp(Et)]₇T)]with poly(deoxyadenylate). Evaluation of the electrostatic interaction

1977 • 47 citations

Carbamate analogs of oligonucleotides

1977 • 42 citations

Incorporation of phosphorothioate groups into fd and φX174 DNA

1977 • 38 citations

Nucleotide analogues for the study of enzyme mechanisms

1980 • 38 citations

Inhibition of transfer RNA function by replacement of uridine and uridine-derived nucleosides with 5-fluorouridine

1978 • 32 citations

Incorporation of 5'-amino-5'-deoxythymidine 5'-phosphate in polynucleotides by use of DNA polymerase I and a φX174 DNA template

1976 • 31 citations

Synthetic analogues of polynucleotides. X. The synthesis of poly-(3'-O-carboxymethyl-2'-deoxyadenosine) and its interaction with polynucleotides.

1973 • 22 citations

Effective binding of oligonucleotides to the anticodon of a tRNA without stimulation of tRNA binding to 30 S ribosomes

1978 • 21 citations

Uptake and fate of water-soluble, nondegradable polymers with antiviral activity in cells and animals

1977 • 19 citations

Synthetic analogues of polynucleotides

1973 • 19 citations