The human urokinase-plasminogen activator gene and its promoter

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

A new method for sequencing DNA.

1977 • 7,941 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

A catalogue of splice junction sequences

1982 • 3,861 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Why genes in pieces?

1978 • 2,256 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli

1983 • 1,241 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Nerve growth factor receptors on human melanoma cells in culture.

1977 • 670 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions

1984 • 523 citations

Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.

1984 • 435 citations

Partial nucleotide sequence of the 300-nucleotide interspersed repeated human DNA sequences

1980 • 346 citations

Structural and functional analysis of the human metallothionein-IA gene: Differential induction by metal ions and glucocorticoids

1984 • 331 citations

The Primary Structure of High Molecular Mass Urokinase from Human Urine. The Complete Amino Arid Sequence of the A Chain

1982 • 312 citations

The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains.

1984 • 303 citations

Characterization of the complementary deoxyribonucleic acid and gene coding for human prothrombin

1983 • 299 citations

Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides

1983 • 295 citations

Evolutionary history of a multigene family: An expressed human β-tubulin gene and three processed pseudogenes

1983 • 287 citations

The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence

1984 • 272 citations

Splice Junctions: Association with Variation in Protein Structure

1983 • 261 citations

The Complete Amino Acid Sequence of Low Molecular Mass Urokinase from Human Urine

1982 • 230 citations

Identification and primary sequence of an unspliced human urokinase poly(A)+ RNA.

1984 • 229 citations

Structure and specific binding of trypsin: Comparison of inhibited derivatives and a model for substrate binding

1974 • 199 citations

Hormonal regulation of plasminogen activator mRNA production in porcine kidney cells

1983 • 151 citations

Isolation and characterization of the rat tyrosine aminotransferase gene.

1984 • 127 citations

Transcriptional activation of the translocated c-myc oncogene in mouse plasmacytomas: Similar RNA levels in tumor and proliferating normal cells

1984 • 116 citations

cDNA and gene nucleotide sequence of porcine plasminogen activator

1984 • 116 citations

T antigen binding and the control of SV40 gene expression

1981 • 108 citations

Characterization of a complementary deoxyribonucleic acid coding for human and bovine plasminogen

1984 • 94 citations

Human dihydrofolate reductase gene organization

1984 • 93 citations

Effect of the 21-bp repeat upstream element on in vitro transcription from the early and late SV40 promoters.

1984 • 87 citations

Nonrandom Ectopic Protein Production by Malignant Cells: Direct Evidence in Vitro

1980 • 81 citations

Amino-acid sequence of activation cleavage site in plasminogen: homology with "pro" part of prothrombin.

1975 • 68 citations

The fibrin-binding site of human plasminogen. Arginines 32 and 34 are essential for fibrin affinity of the kringle 1 domain.

1984 • 67 citations

Adaptation of plasminogen activator sequences to known protease structures

1983 • 64 citations

The E1b promoter of Ad12 in mouse L tk- cells is activated by adenovirus region E1a.

1983 • 60 citations

Tumor promoter PMA stimulates the synthesis and secretion of mouse pro-urokinase in MSV-transformed 3T3 cells: this is mediated by an increase in urokinase mRNA content.

1984 • 58 citations

Transcription from SV40-like monkey DNA sequences

1984 • 51 citations

Monoclonal antibodies to human urokinase identify the single-chain pro-urokinase precursor.

1984 • 38 citations

Sequence organization of the ribosomal spacer ofD.melanogaster

1982 • 36 citations

Modular structure of the beta-globin and the TK promoters.

1984 • 31 citations

Transcriptional induction of urokinase in cultured human kidney carcinoma cells by tetradecanoyl‐phorbol‐acetate

1984 • 22 citations

High efficiency of replication and expression of foreign genes in SV40-transformed human fibroblasts.

1983 • 17 citations