Cutting Edge: Innate Immune Cells Contribute to the IFN-γ-Dependent Regulation of Antigen-Specific CD8+ T Cell Homeostasis

CELLULAR RESPONSES TO INTERFERON-γ

1997 • 2,885 citations

Effector and memory T-cell differentiation: implications for vaccine development

2002 • 1,757 citations

The Molecular Cell Biology of Interferon-gamma and its Receptor

1993 • 1,323 citations

Induced recruitment of NK cells to lymph nodes provides IFN-γ for TH1 priming

2004 • 1,284 citations

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

2001 • 1,277 citations

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

2001 • 861 citations

Myeloid Suppressor Lines Inhibit T Cell Responses by an NO-Dependent Mechanism

2002 • 657 citations

The role of nitric oxide in innate immunity

2000 • 642 citations

Early Programming of T Cell Populations Responding to Bacterial Infection

2000 • 492 citations

Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway

1998 • 473 citations

Regulation of Antigen-Specific CD8 ⁺ T Cell Homeostasis by Perforin and Interferon-γ

2000 • 452 citations

Failure to Suppress the Expansion of the Activated Cd4 T Cell Population in Interferon γ–Deficient Mice Leads to Exacerbation of Experimental Autoimmune Encephalomyelitis

2000 • 424 citations

Interferon γ Is Required for Activation-induced Death of T Lymphocytes

2002 • 423 citations

Transforming growth factor-β controls T helper type 1 cell development through regulation of natural killer cell interferon-γ

2005 • 420 citations

An absolute and restricted requirement for IL-12 in natural killer cell IFN-gamma production and antiviral defense. Studies of natural killer and T cell responses in contrasting viral infections.

1996 • 384 citations

Interferon γ Eliminates Responding Cd4 T Cells during Mycobacterial Infection by Inducing Apoptosis of Activated Cd4 T Cells

2000 • 340 citations

CD8+ T cell contraction is controlled by early inflammation

2004 • 322 citations

Interferon-γ acts directly on CD8+ T cells to increase their abundance during virus infection

2005 • 314 citations

IFN-gamma is critical to the control of murine autoimmune encephalomyelitis and regulates both in the periphery and in the target tissue: a possible role for nitric oxide.

1999 • 246 citations

Interferon‐γ, the functional plasticity of the ubiquitin–proteasome system, and MHC class I antigen processing

2005 • 226 citations

IFN-γ Is Critical to the Control of Murine Autoimmune Encephalomyelitis and Regulates Both in the Periphery and in the Target Tissue: A Possible Role for Nitric Oxide

1999 • 204 citations

Memory CD8+ T Cells Provide an Early Source of IFN-γ

2003 • 141 citations

Viral Infection Results in Massive CD8+ T Cell Expansion and Mortality in Vaccinated Perforin-Deficient Mice

2003 • 120 citations

Influence of effector molecules on the CD8+ T cell response to infection

2002 • 103 citations

Dynamic Regulation of IFN-γ Signaling in Antigen-Specific CD8+ T Cells Responding to Infection

2005 • 94 citations

Compromised virus control and augmented perforin-mediated immunopathology in IFN-gamma-deficient mice infected with lymphocytic choriomeningitis virus.

1999 • 78 citations

Cutting Edge: CD8+ Effector T Cells Reject Tumors by Direct Antigen Recognition but Indirect Action on Host Cells

2003 • 78 citations

Apoptotic Regulation of T Cells and Absence of Immune Deficiency in Virus-Infected Gamma Interferon Receptor Knockout Mice

1998 • 77 citations

Compromised Virus Control and Augmented Perforin-Mediated Immunopathology in IFN-γ-Deficient Mice Infected with Lymphocytic Choriomeningitis Virus

1999 • 74 citations

Interferon γ Enhances Both In Vitro and In Vivo Priming of CD4+ T Cells for IL-4 Production

2004 • 64 citations

Homeostasis of naı̈ve, effector and memory CD8 T cells

2002 • 47 citations

The Contraction Phase of Virus-Specific CD8+ T Cells Is Unaffected by a Pan-Caspase Inhibitor

2004 • 26 citations