Activation of Transcription Factor NF-κB Requires ELKS, an IκB Kinase Regulatory Subunit

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1996 • 8,994 citations

Phosphorylation Meets Ubiquitination: The Control of NF-κB Activity

2000 • 4,644 citations

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

2002 • 4,334 citations

NF-κB regulation in the immune system

2002 • 3,804 citations

Activators and Target Genes of Rel/NF-кB Transcription Factors

2003 • 3,164 citations

An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death

1996 • 3,094 citations

NF-κB: Ten Years After

1996 • 3,008 citations

TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB

1996 • 2,665 citations

Suppression of TNF-α-Induced Apoptosis by NF-κB

1996 • 2,623 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1997 • 2,048 citations

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

1997 • 1,802 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

1997 • 1,198 citations

Identification and Characterization of an IκB Kinase

1997 • 1,166 citations

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1998 • 1,070 citations

IKK-γ is an essential regulatory subunit of the IκB kinase complex

1998 • 950 citations

A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA

2003 • 547 citations

TNF-Induced Recruitment and Activation of the IKK Complex Require Cdc37 and Hsp90

2002 • 393 citations

IκB Kinase (IKK)-Associated Protein 1, a Common Component of the Heterogeneous IKK Complex

1999 • 333 citations

Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor α-induced apoptosis

1999 • 180 citations

Activation of the IκB Kinases by RIP via IKKγ/NEMO-mediated Oligomerization

2000 • 171 citations

Mechanisms of Proinflammatory Cytokine-Induced Biphasic NF-κB Activation

2003 • 154 citations

Tetrameric Oligomerization of IκB Kinase γ (IKKγ) Is Obligatory for IKK Complex Activity and NF-κB Activation

2003 • 135 citations

Fusion of a novel gene,ELKS, toRET due to translocation t(10;12)(q11;p13) in a papillary thyroid carcinoma

1999 • 130 citations

IKKγ/NEMO Facilitates the Recruitment of the IκB Proteins into the IκB Kinase Complex

2001 • 53 citations

Roles for Homotypic Interactions and Transautophosphorylation in IκB Kinase (IKKβ) Activation

2003 • 43 citations

Differential expression of multiple isoforms of the ELKS mRNAs involved in a papillary thyroid carcinoma

2002 • 27 citations

Genomic organization and chromosomal mapping of ELKS, a gene rearranged in a papillary thyroid carcinoma

2000 • 12 citations