Amyloidogenic role of cytokine TGF-β1 in transgenic mice and in Alzheimer's disease

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1995 • 2,456 citations

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease.

1993 • 1,480 citations

Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease

1996 • 1,371 citations

Amyloid, the presenilins and Alzheimer's disease

1997 • 1,370 citations

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

1995 • 1,290 citations

Cerebral amyloid angiopathy. A critical review.

1987 • 1,013 citations

Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid

1992 • 802 citations

Alzheimer's Disease: A Central Role for Amyloid

1994 • 749 citations

Cerebral Amyloid Angiopathy

1998 • 654 citations

Amyloid precursor protein processing and Aβ ₄₂ deposition in a transgenic mouse model of Alzheimer disease

1997 • 624 citations

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

1995 • 488 citations

Apolipoprotein E and Alzheimer's Disease

1996 • 457 citations

Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease.

1996 • 373 citations

Spectrum of human immunodeficiency virus–associated neocortical damage

1992 • 369 citations

The presenilins and Alzheimer's disease

1997 • 364 citations

Transforming growth factor β: a matter of life and death

1994 • 306 citations

Comparison of Neurodegenerative Pathology in Transgenic Mice Overexpressing V717F β-Amyloid Precursor Protein and Alzheimer’s Disease

1996 • 301 citations

Exploring the Etiology of Alzheimer Disease Using Molecular Genetics

1997 • 260 citations

Cerebral amyloid angiopathy: A significant cause of cerebellar as well as lobar cerebral hemorrhage in the elderly

1993 • 255 citations

Levels and Alternative Splicing of Amyloid β Protein Precursor (APP) Transcripts in Brains of APP Transgenic Mice and Humans with Alzheimer's Disease

1995 • 250 citations

Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-beta 1.

1995 • 248 citations

Transforming growth factor-β1 is in plaques in Alzheimer and Down pathologies

1993 • 232 citations

Genetic susceptibility and head injury as risk factors for Alzheimer's disease among community‐dwelling elderly persons and their first‐degree relatives

1993 • 221 citations

The apolipoprotein E epsilon 4 allele is associated with increased neuritic plaques and cerebral amyloid angiopathy in Alzheimer's disease and Lewy body variant

1996 • 206 citations

TGF‐β1 is an organizer of responses to neurodgeneration

1993 • 198 citations

Kunitz Protease Inhibitor-Containing Amyloid β Protein Precursor Immunoreactivity in Alzheimer's Disease

1992 • 137 citations

Rodent models of Alzheimer's disease: Rat aβ infusion approaches to amyloid deposits

1996 • 131 citations

Differential Expression of TGF-β1, 2 and 3 Isotypes in Alzheimerʼs Disease: A Comparative Immunohistochemical Study with Cerebral Infarction, Aged Human and Mouse Control Brains

1995 • 118 citations

Transforming growth factor beta in Alzheimer's disease

1994 • 103 citations

Clinical Aspects of Cerebral Amyloid Angiopathy

1994 • 20 citations