Resistance of Paroxysmal Nocturnal Hemoglobinuria Cells to the Glycosylphosphatidylinositol-Binding Toxin Aerolysin

Molecular Weight Determination of Protein-Dodecyl Sulfate Complexes by Gel Electrophoresis in a Discontinuous Buffer System

1971 • 2,019 citations

Modulation of granulocyte survival and programmed cell death by cytokines and bacterial products

1992 • 1,103 citations

Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria

1993 • 1,033 citations

GPI-Anchored Cell-Surface Molecules Complexed to Protein Tyrosine Kinases

1991 • 848 citations

The Cloning of PIG-A, a Component in the Early Step of GPI-Anchor Biosynthesis

1993 • 528 citations

Paroxysmal nocturnal haemoglobinuria: long-term follow-up and prognostic factors

1996 • 494 citations

Malignant Tumors Occurring after Treatment of Aplastic Anemia

1993 • 461 citations

Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG-A gene.

1994 • 390 citations

Mechanism of Membrane Anchoring Affects Polarized Expression of Two Proteins in MDCK Cells

1989 • 377 citations

Somatic Mutations in Paroxysmal Nocturnal Hemoglobinuria: A Blessing in Disguise?

1997 • 305 citations

Phosphatidylinositol membrane anchors and T-cell activation

1991 • 263 citations

Abnormalities of PIG-A Transcripts in Granulocytes from Patients with Paroxysmal Nocturnal Hemoglobinuria

1994 • 249 citations

7 Paroxysmal nocturnal haemoglobinuria

1989 • 246 citations

The molecular basis of paroxysmal nocturnal hemoglobinuria

1995 • 231 citations

The use of monoclonal antibodies and flow cytometry in the diagnosis of paroxysmal nocturnal hemoglobinuria

1996 • 229 citations

The problem of clonality in aplastic anemia: Dr Dameshek's riddle, restated [see comments]

1992 • 222 citations

Activation of the hole-forming toxin aerolysin by extracellular processing

1985 • 213 citations

Complete remission in severe aplastic anemia after high-dose cyclophosphamide without bone marrow transplantation

1996 • 183 citations

Glycosylphosphatidylinositol Anchors of Membrane Glycoproteins Are Binding Determinants for the Channel-forming Toxin Aerolysin

1998 • 181 citations

Paroxysmal Nocturnal Hemoglobinuria as a Molecular Disease

1997 • 177 citations

The problem of clonality in aplastic anemia: Dr Dameshek's riddle, restated [see comments]

1992 • 175 citations

Membrane glycoprotein receptor and hole-forming properties of a cytolytic protein toxin

1982 • 137 citations

Aplastic anemia and paroxysmal nocturnal hemoglobinuria: search for a pathogenetic link

1995 • 130 citations

The Glycosylphosphatidylinositol-anchored Surface Glycoprotein Thy-1 Is a Receptor for the Channel-forming Toxin Aerolysin

1997 • 121 citations

Targeting of transmembrane and GPI-anchored forms of N-CAM to opposite domains of a polarized epithelial cell

1991 • 107 citations

Resistance to apoptosis caused byPIG-Agene mutations in paroxysmal nocturnal hemoglobinuria

1997 • 105 citations

Apoptosis Resistance of Blood Cells From Patients With Paroxysmal Nocturnal Hemoglobinuria, Aplastic Anemia, and Myelodysplastic Syndrome

1997 • 100 citations

Aerolysin — the ins and outs of a model channel‐forming toxin

1996 • 98 citations

Genetic defects underlying paroxysmal nocturnal hemoglobinuria that arises out of aplastic anemia

1995 • 94 citations

Oligomerization of the channel-forming toxin aerolysin precedes insertion into lipid bilayers

1993 • 91 citations

The cytolytic toxin aerolysin must aggregate to disrupt erythrocytes, and aggregation is stimulated by human glycophorin

1988 • 90 citations

Diagnosis of paroxysmal nocturnal haemoglobinuria using immunophenotyping of peripheral blood cells

1991 • 86 citations

Biosynthesis and function of LFA-3 in human mutant cells deficient in phosphatidylinositol-anchored proteins.

1988 • 78 citations

Treatment of paroxysmal nocturnal hemoglobinuria

1982 • 70 citations

The Life-span of Complement-sensitive and -insensitive Red Cells in Paroxysmal Nocturnal Hemoglobinuria

1971 • 61 citations

The erythrocyte receptor for the channel‐forming toxin aerolysin is a novel glycosylphosphatidylinositol‐anchored protein

1997 • 60 citations

Neutrophil life span in paroxysmal nocturnal hemoglobinuria

1977 • 45 citations